• 1. Department of Thoracic and Cardiovascular Surgery, the First Affiliated Hospital of Hebei North University, Zhangjiakou, Hebei 075000, P. R. China;
  • 2. Department of Radiology, the 81st Group Army Hospital of the PLA Army, Zhangjiakou, Hebei 075000, P. R. China;
GAO Yongshan, Email: gaoyongshan3333@163.com
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Objective  To analyze the effects of different surgical methods on postoperative pulmonary function and exercise capacity in patients with non-small cell lung cancer (NSCLC), so as to explore whether it can effectively improve pulmonary function and promote the recovery of exercise capacity by reducing the number of trocars ports and the resection of normal lung tissues. Methods  The clinical data of NSCLC patients who underwent surgery in the First Affiliated Hospital of Hebei North University from January 2016 to June 2019 were collected retrospectively. According to the surgical methods, they were divided into three groups: single utility port video-assisted thoracic surgery (SP-VATS) segmentectomy group, SP-VATS lobectomy group and three port video-assisted thoracic surgery (TP-VATS) lobectomy group. The changes of pulmonary function [forced vital capacity (FVC), forced expiratory volume in one second (FEV1), peak expiratory flow (PEF), maximal voluntary ventilation (MVV)] and 6-minute walking distance (6MWD) at different time points [1st day before the operation (T0); 3rd day (T1), 7th day (T2), 1st month (T3), 3rd month (T4), 6th month (T5) and 1st year (T6) after the operation] were compared among the three groups. Results  A total of 342 patients were included, including 102 in SP-VATS segmentectomy group, 116 in SP-VATS lobectomy group and 124 in TP-VATS lobectomy group. Except for pathological type and TNM stage (P<0.05), there was no significant difference in general information, preoperative pulmonary function or 6MWD among the three groups (P>0.05). The pulmonary function and 6MWD of the three groups before and after operation were not affected by pathological type or TNM stage (P>0.05). Except at T6 time point (P>0.05), there were significant differences in postoperative pulmonary function and 6MWD among the three groups at T1-T5 time points (P<0.05). Intra group comparison of pulmonary function and 6MWD in the three groups showed that the operation had the least impact on patients in SP-VATS segmentectomy group with the fastest recovery, followed by SP-VATS lobectomy group, and SP-VATS lobectomy group was the worst. Conclusions  Video-assisted thoracoscopic for NSCLC can improve pulmonary function and promote the recovery of exercise capacity by reducing the number of trocars ports and the resection of normal lung tissues. However, this advantage is mainly reflected in the early postoperative stage.

Citation: GAO Yongshan, JIANG Weihua, YANG Yanjun, ZHANG Zhijie, FU Wei, ZHANG Zhenming, DONG Yuehua, WANG Dawei. Effects of three kinds of surgical methods on postoperative pulmonary function and exercise capacity in patients with non-small cell lung cancer. West China Medical Journal, 2022, 37(1): 33-39. doi: 10.7507/1002-0179.202008242 Copy

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