APPLICATION OF THREE-DIMENSIONAL PRINTING TECHNIQUE IN ARTIFICIAL BONE FABRICATION FOR BONE DEFECT AFTER MANDIBULAR ANGLE OSTECTOMY_Chinese Journal of Reparative and Reconstructive Surgery

Authors：

SHENCongcong , ZHANGYan , LIQingfeng , ZHUMing , HOUYikang , QUMiao , XUYourong ,  CHAIGang

Department of Plastic and Reconstruction Surgery, Shanghai 9th People's Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, 200011, P. R. Chin;

Corresponding author：

CHAIGang, Email: 13918218178@163.com

Keywords：

Three-dimensional printing technique; Mandibular angle ostectomy; Artificial bone; Bone defect repair

DOI：

10.7507/1002-1892.20140068

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Objective To investigate the application of three-dimensional (3-D) printing technique combining with 3-D CT and computer aided-design technique in customized artificial bone fabrication, correcting mandibular asymmetry deformity after mandibular angle ostectomy. Methods Between April 2011 and June 2013, 23 female patients with mandibular asymmetry deformity after mandibular angle ostectomy were treated. The mean age was 27 years (range, 22-34 years). The disease duration of mandibular asymmetry deformity was 6-16 months (mean, 12 months). According to the CT data and individualized mandibular angle was simulated based on mirror theory, 3-D printed implants were fabricated as the standard reference for manufacturers to fabricated artificial bone graft, and then mandible repair operation was performed utilizing the customized artificial bone to improve mandibular asymmetry. Results The operation time varied from 40 to 60 minutes (mean, 50 minutes). Primary healing of incisions was obtained in all patients; no infection, hematoma, and difficulty in opening mouth occurred. All 23 patients were followed up 3-10 months (mean, 6.7 months). After operation, all patients obtained satisfactory facial and mandibular symmetry. 3-D CT reconstructive examination results after 3 months of operation showed good integration of the artificial bone. Conclusion 3-D printing technique combined with 3-D CT and computer aided design technique can be a viable alternative to the approach of maxillofacial defects repair after mandibular angle ostectomy, which provides a accurate and easy way.

Citation： SHENCongcong, ZHANGYan, LIQingfeng, ZHUMing, HOUYikang, QUMiao, XUYourong, CHAIGang. APPLICATION OF THREE-DIMENSIONAL PRINTING TECHNIQUE IN ARTIFICIAL BONE FABRICATION FOR BONE DEFECT AFTER MANDIBULAR ANGLE OSTECTOMY. Chinese Journal of Reparative and Reconstructive Surgery, 2014, 28(3): 300-303. doi: 10.7507/1002-1892.20140068 Copy

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2.	Sykes LM, Parrot AM, Owen CP, et al. Applications of rapid prototyping technology in maxillofacial prosthetics. Int J Prosthodont, 2004, 17(4):454-459.
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4.	Petzold R, Zeilhofer HF, Kalender WA. Rapid protyping technology in medicine-basics and applications. Comput Med Imaging Graph, 1999, 23(5):277-284.
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7.	Silva DN, Gerhardt de Oliveira M, Meurer E, et al. Dimensional error in selective laser sintering and 3D-printing of models for craniomaxillary anatomy reconstruction. J Craniomaxillofac Surg, 2008, 36(8):443-449.
8.	Kozakiewicz M, Elgalal M, Loba P, et al. Clinical application of 3D pre-bent titanium implants for orbital floor fractures. J Craniomaxillofac Surg, 2009, 37(4):229-234.
9.	Li WZ, Zhang MC, Li SP, et al. Application of computer-aided three dimensional skull model with rapid prototyping technique in repair of zygomatico-orbito-maxillary complex fracture. Int J Med Robot, 2009, 5(2):158-163.
10.	Bai S, Shang H, Liu Y, et al. Computer-aided design and computer-aided manufacturing locating guides accompanied with prebent titaniumplates in orthognathic surgery. J Oral Maxillofac Surg, 2012, 70(10):2419-2426.
11.	Tang W, Guo L, Long J, et al. Individual design and rapid prototyping in reconstruction of orbital wall defects. J Oral Maxillofac Surg, 2010, 68(3):562-570.
12.	Wang G, Li J, Khadka A, et al. CAD/CAM and rapid prototyped titanium for reconstruction of ramus defect and condylar fracture caused by mandibular reduction. Oral Surg Oral Med Oral Pathol Oral Radiol, 2012, 113(3):356-361.
13.	Juergens P, Krol Z, Zeilhofer HF, et al. Computer simulation and rapid prototyping for the reconstruction of the mandible. J Oral Maxillofac Surg, 2009, 67(10):2167-2170.
14.	Morris CL, Barber RF, Day R. Orofacial prosthesis design and fabrication using stereolithography. Aust Dent J, 2000, 45(4):250-253.
15.	王迎军, 杜昶, 赵娜如, 等. 仿生人工骨修复材料研究. 华南理工大学学报:自然科学版, 2012, 40(10):51-58.
16.	Li J, Hsu Y, Luo E, et al. Computer-aided design and manufacturing and rapid prototyped nanoscale hydroxyapatite/polyamide (n-HA/PA)construction for condylar defect caused by mandibular angle ostectomy. Aesth Plast Surg, 2011, 35(4):636-640.
17.	Rotaru H, Baciut M, Stan H, et al. Silicone rubber mould cast polyethylmethacrylate-hydroxyapatite plate used forrepairing a large skull defect. J Craniomaxillofac Surg, 2006, 34(4):242-246.

1. Goiato MC, Santos MR, Pesqueira AA, et al. Prototyping for surgical and prosthetic treatment. J Craniofac Surg, 2011, 22(3):914-917.
2. Sykes LM, Parrot AM, Owen CP, et al. Applications of rapid prototyping technology in maxillofacial prosthetics. Int J Prosthodont, 2004, 17(4):454-459.
3. Goiato MC, Dos Santos DM, Haddad MF, et al. Most frequent tumors in maxillofacial area rehabilitated through surgical reconstruction and prostheses. J Craniofac Surg, 2010, 21(2):396-399.
4. Petzold R, Zeilhofer HF, Kalender WA. Rapid protyping technology in medicine-basics and applications. Comput Med Imaging Graph, 1999, 23(5):277-284.
5. Sanna MP, Ferry WM, Dirk WG, et al. A review of rapid prototyping techniques for tissue engineering purposes. Annals of Medicine, 2008, 40(4):268-280.
6. Choi JY, Choi JH, Kim NK, et al. Analysis of errors in medical rapid prototyping models. Int J Oral Maxillofac Surg, 2002, 31(1):23-32.
7. Silva DN, Gerhardt de Oliveira M, Meurer E, et al. Dimensional error in selective laser sintering and 3D-printing of models for craniomaxillary anatomy reconstruction. J Craniomaxillofac Surg, 2008, 36(8):443-449.
8. Kozakiewicz M, Elgalal M, Loba P, et al. Clinical application of 3D pre-bent titanium implants for orbital floor fractures. J Craniomaxillofac Surg, 2009, 37(4):229-234.
9. Li WZ, Zhang MC, Li SP, et al. Application of computer-aided three dimensional skull model with rapid prototyping technique in repair of zygomatico-orbito-maxillary complex fracture. Int J Med Robot, 2009, 5(2):158-163.
10. Bai S, Shang H, Liu Y, et al. Computer-aided design and computer-aided manufacturing locating guides accompanied with prebent titaniumplates in orthognathic surgery. J Oral Maxillofac Surg, 2012, 70(10):2419-2426.
11. Tang W, Guo L, Long J, et al. Individual design and rapid prototyping in reconstruction of orbital wall defects. J Oral Maxillofac Surg, 2010, 68(3):562-570.
12. Wang G, Li J, Khadka A, et al. CAD/CAM and rapid prototyped titanium for reconstruction of ramus defect and condylar fracture caused by mandibular reduction. Oral Surg Oral Med Oral Pathol Oral Radiol, 2012, 113(3):356-361.
13. Juergens P, Krol Z, Zeilhofer HF, et al. Computer simulation and rapid prototyping for the reconstruction of the mandible. J Oral Maxillofac Surg, 2009, 67(10):2167-2170.
14. Morris CL, Barber RF, Day R. Orofacial prosthesis design and fabrication using stereolithography. Aust Dent J, 2000, 45(4):250-253.
15. 王迎军, 杜昶, 赵娜如, 等. 仿生人工骨修复材料研究. 华南理工大学学报:自然科学版, 2012, 40(10):51-58.
16. Li J, Hsu Y, Luo E, et al. Computer-aided design and manufacturing and rapid prototyped nanoscale hydroxyapatite/polyamide (n-HA/PA)construction for condylar defect caused by mandibular angle ostectomy. Aesth Plast Surg, 2011, 35(4):636-640.
17. Rotaru H, Baciut M, Stan H, et al. Silicone rubber mould cast polyethylmethacrylate-hydroxyapatite plate used forrepairing a large skull defect. J Craniomaxillofac Surg, 2006, 34(4):242-246.

Chinese Journal of Reparative and Reconstructive Surgery

APPLICATION OF THREE-DIMENSIONAL PRINTING TECHNIQUE IN ARTIFICIAL BONE FABRICATION FOR BONE DEFECT AFTER MANDIBULAR ANGLE OSTECTOMY

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