• 1. Brigade of Postgraduate Management, Third Military Medical University, Chongqing, 400038, P. R. China;
  • 2. Department of Orthopedics, Kunming General Hospital of Chengdu Military Region;
XUYongqing, Email: xuyongqingkm@163.net
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Objective To summarize the current researches and progress on experimental animal models of avascular necrosis of the femoral head. Methods Domestic and international literature concerning experimental animal models of avascular necrosis of the femoral head was reviewed and analyzed. Results The methods to prepare the experimental animal models of avascular necrosis of the femoral head can be mainly concluded as traumatic methods (including surgical, physical, and chemical insult), and non-traumatic methods (including steroid, lipopolysaccharide, steroid combined with lipopolysaccharide, steroid combined with horse serum, etc). Each method has both merits and demerits, yet no ideal methods have been developed. Conclusion There are many methods to prepare the experimental animal models of avascular necrosis of the femoral head, but proper model should be selected based on the aim of research. The establishment of ideal experimental animal models needs further research in future.

Citation: YUKaifu, TANHongbo, XUYongqing. RESEARCH PROGRESS OF EXPERIMENTAL ANIMAL MODELS OF AVASCULAR NECROSIS OF FEMORAL HEAD. Chinese Journal of Reparative and Reconstructive Surgery, 2015, 29(12): 1564-1569. doi: 10.7507/1002-1892.20150333 Copy

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