Research progress on gastrointestinal hemorrhage after cardiac surgery_Chinese Journal of Clinical Thoracic and Cardiovascular Surgery

Authors：

ZENG Ling ¹ , LIAO Yao ² ,  QIAN Yongjun ³

1. Department of Intensive Care Unit, West China Hospital, Sichuan University, Chengdu, 610041, P.R.China;
2. Department of Cardiovascular Surgery, Jingzhou Central Hospital, Jingzhou, 434000, Hubei, P.R.China;
3. Department of Cardiovascular Surgery, West China Hospital, Sichuan University, Chengdu, 610041, P.R.China;

Corresponding author：

QIAN Yongjun, Email: yongjunqian@sina.com

Keywords：

Cardiac surgery; gastrointestinal hemorrhage; research progress

DOI：

10.7507/1007-4848.201805069

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

Although the incidence of gastrointestinal hemorrhage after cardiac surgery is low, the mortality rate is high. Early detection and diagnosis of gastrointestinal hemorrhage are difficult. The high risk phases including preoperation, intraoperation and postoperation. Preoperative high risk comorbidities include gastrointestinal ulcer, hypertension, coronary heart disease and chronic renal failure. Intraoperative high risk factors include decreased gastrointestinal blood perfusion due to cardiopulmonary bypass, inflammatory factors releasing, coagulation disorders, and thrombosis. Postoperative high risk factors include hypotension, low cardiac output, prolonged mechanical ventilation, etc. This article retrospectively summarized high-risk factors and pathogenesis of gastrointestinal hemorrhage after cardiac surgery, in order to improve prevention and treatment of gastrointestinal hemorrhage.

Citation： ZENG Ling, LIAO Yao, QIAN Yongjun. Research progress on gastrointestinal hemorrhage after cardiac surgery. Chinese Journal of Clinical Thoracic and Cardiovascular Surgery, 2019, 26(1): 97-100. doi: 10.7507/1007-4848.201805069 Copy

1.	Krawiec F, Maitland A, Duan Q, et al. Duodenal ulcers are a major cause of gastrointestinal bleeding after cardiac surgery. J Thorac Cardiovasc Surg, 2017, 154(1): 181-188.
2.	Bolcal C, Iyem H, Sargin M, et al. Gastrointestinal complications after cardiopulmonary bypass: sixteen years of experience. Can J Gastroenterol, 2005, 19(10): 613-7.
3.	Geissler HJ, Fischer UM, Grunert S, et al. Incidence and outcome of gastrointestinal complications after cardiopulmonary bypass. Interact Cardiovasc Thorac Surg, 2006, 5(3): 239-42.
4.	Hanks JB, Curtis SE, Hanks BB, et al. Gastrointestinal complications after cardiopulmonary bypass. Surgery, 1982, 92(2): 394-400.
5.	Heikkinen LO, Ala-Kulju KV. Abdominal complications following cardiopulmonary bypass in open-heart surgery. Scand J Thorac Cardiovasc Surg, 1987, 21(1): 1-7.
6.	Hashemzadeh K, Hashemzadeh S. Predictors and outcome of gastrointestinal complications after cardiac surgery. Minerva Chir, 2012, 67(4): 327-335.
7.	Lebovics E, Lee SS, Dworkin BM, et al. Upper gastrointestinal bleeding following open heart surgery. Dig Dis Sci, 1991, 36(6): 757-760.
8.	Sicsic JC, Duranteau J, Corbineau H, et al. Gastric mucosal oxygen delivery decreases during cardiopulmonary bypass despite constant systemic oxygen delivery. Anesth Analg, 1998, 86(3): 455-460.
9.	Cassina T, Santambrogio L. Microcirculation after cardiopulmonary bypass: a glance at the mesenteric mucosa. Minerva Anestesiol, 2012, 78(3): 288-290.
10.	Jungwirth B, Eckel B, Blobner M, et al. The impact of cardiopulmonary bypass on systemic interleukin-6 release, cerebral nuclear factor-kappa B expression,and neurocognitive outcome in rats. Anesth Analg, 2010, 110(2): 312-320.
11.	Warren OJ, Smith AJ, Alexiou C, et al. The inflammatory response to cardiopulmonary bypass: part 1-mechanisms of pathogenesis. J Cardiothorac Vasc Anesth, 2009, 23(2): 223-231.
12.	黑飞龙, 龙村, 孙桂民, 等. 体外循环心内直视手术中胃肠激素变化. 中华实验外科杂志, 2003, 20(4): 375.
13.	De Backer D, Dubois MJ, Schmartz D, et al. Microcirculatory alterations in cardiac surgery: effects of cardiopulmonary bypass and anesthesia. Ann Thorac Surg, 2009, 88(5): 1396-1403.
14.	Martinez A, Seymour C, Nam M. Minute ventilation recovery time: a predictor of extubation outcome. Chest, 2003, 123(4): 1214-1221.
15.	龙小毛, 林辉, 李香伟. 16例心血管病术后消化道出血病因分析. 心肺血管病杂志, 2008, 27(5): 295-296.
16.	石进, 李雅君, 吴素萍. 肠溶阿司匹林与冠心病患者结肠出血:31例临床分析. 胃肠病学, 2008, 13(4): 244-245.
17.	Mead J, Folk F. Gastrointestinal bleeding after cardiac surgery. N Engl J Med, 1969, 281(14): 799.
18.	中华医学杂志编委会. 应激性溃疡防治建议. 现代实用医学, 2003, 15(4): 260-261.
19.	Søreide K1, Thorsen K, Søreide JA. Strategies to improve the outcome of emergency surgery for perforated peptic ulce. Br J Surg, 2014, 101(1): e51-e64.
20.	周晔, 王建华, 刘冰, 等. 泮托拉唑对体外循环手术患者胃内酸碱度的影响. 心肺血管病杂志, 2010, 29(3): 197-199.
21.	施学进, 沈翠华, 曹坤跃. 老年脑卒中患者医院内获得性肺炎及其相关独立危险因素的分析. 心肺血管病杂志, 2003, 22(1): 33-35.
22.	董力, 石应康, 刘家珍, 等. 体外循环心内直视术后上消化道大出血的处理. 中国胸心血管外科临床杂志, 1996, 2(4): 229-230.
23.	Chen CH, Lin HC, Lin HL, et al. Proton pump inhibitor usage and the associated risk of pneumonia in patients with chron- ic kidney disease. J Microbiol Immunol Infect, 2015, 48(4): 390-396.
24.	Lazarus B, Chen Y, Wilson FP, et al. Proton pump inhibitor use and the risk of chronic kidney disease. JAMA Intern Med, 2016, 176(2): 238-246.
25.	Xie Y, Bowe B, Li T, et al. Proton pump inhibitors and risk of incident CKD and progression to ESRD. J Am Soc Nephrol, 2016, 27(10): 3153-3163.
26.	Peng Y L, Luo J C. The benefits and risks of proton pump inhibitor therapy. J Chin Med Assoc, 2016, 79(1): 1-2.
27.	Levenstein S, Rosenstock S, J acobsen RK, et al. Psychological stress increases risk for peptic ulcer, regardless of Helicobacter pylori infection or use of nonsteroidal anti-inflammatory drugs. Clin Gastroenterol Hepatol, 2015, 13(3): 498-506.
28.	陈新贵, 许勋良, 段礼兴, 等. 生长抑素及凝血酶在上消化道溃疡出血治疗中的应用及安全性分析. 中国普通外科杂志, 2016, 25(2): 307-310.
29.	Cook DJ, Reeve BK, Guyatt GH, et al. Stress ulcer prophylaxis in critically ill patients. JAMA, 1996, 275(4): 308-314.
30.	Kuipers EJ, Thijs JC, Festen HP. The prevalence of helicobacter pylori in peptic ulcer disease. Aliment Pharmacol Ther, 1995, 9(Suppl2): 59-69.
31.	Halm U, Halm F, Thein D, et al. Helicobacter pylori infection:A risk factor for upper gastrointestinal bleeding after cardiac surgery? Crit Care Med, 2000, 28(1): 110-113.
32.	郭静贤, 景富春, 贺继东, 等. 急性上消化道出血患者幽门螺杆菌感染分析. 中国公共卫生, 2010, 26(9): 1180-1181.
33.	Shiba M, Higuchi K, Kadouchi K, et al. Risk factors for bleeding after endoscopic mucosal resection. World J Gastroenterol, 2005, 11(46): 7335-7339.
34.	Andersson B, Nilsson J, Brandt J, et al. Gastrointestinal complications after cardiac surgery. Br J Surg, 2005r, 92(3): 326-333.
35.	DiSesa VJ. Gastrointestinal bleeding after cardiac surgery: Does describing the disease prescribe the cure? J Thorac Cardiovasc Surg, 2017, 154(1): 189.

1. Krawiec F, Maitland A, Duan Q, et al. Duodenal ulcers are a major cause of gastrointestinal bleeding after cardiac surgery. J Thorac Cardiovasc Surg, 2017, 154(1): 181-188.
2. Bolcal C, Iyem H, Sargin M, et al. Gastrointestinal complications after cardiopulmonary bypass: sixteen years of experience. Can J Gastroenterol, 2005, 19(10): 613-7.
3. Geissler HJ, Fischer UM, Grunert S, et al. Incidence and outcome of gastrointestinal complications after cardiopulmonary bypass. Interact Cardiovasc Thorac Surg, 2006, 5(3): 239-42.
4. Hanks JB, Curtis SE, Hanks BB, et al. Gastrointestinal complications after cardiopulmonary bypass. Surgery, 1982, 92(2): 394-400.
5. Heikkinen LO, Ala-Kulju KV. Abdominal complications following cardiopulmonary bypass in open-heart surgery. Scand J Thorac Cardiovasc Surg, 1987, 21(1): 1-7.
6. Hashemzadeh K, Hashemzadeh S. Predictors and outcome of gastrointestinal complications after cardiac surgery. Minerva Chir, 2012, 67(4): 327-335.
7. Lebovics E, Lee SS, Dworkin BM, et al. Upper gastrointestinal bleeding following open heart surgery. Dig Dis Sci, 1991, 36(6): 757-760.
8. Sicsic JC, Duranteau J, Corbineau H, et al. Gastric mucosal oxygen delivery decreases during cardiopulmonary bypass despite constant systemic oxygen delivery. Anesth Analg, 1998, 86(3): 455-460.
9. Cassina T, Santambrogio L. Microcirculation after cardiopulmonary bypass: a glance at the mesenteric mucosa. Minerva Anestesiol, 2012, 78(3): 288-290.
10. Jungwirth B, Eckel B, Blobner M, et al. The impact of cardiopulmonary bypass on systemic interleukin-6 release, cerebral nuclear factor-kappa B expression,and neurocognitive outcome in rats. Anesth Analg, 2010, 110(2): 312-320.
11. Warren OJ, Smith AJ, Alexiou C, et al. The inflammatory response to cardiopulmonary bypass: part 1-mechanisms of pathogenesis. J Cardiothorac Vasc Anesth, 2009, 23(2): 223-231.
12. 黑飞龙, 龙村, 孙桂民, 等. 体外循环心内直视手术中胃肠激素变化. 中华实验外科杂志, 2003, 20(4): 375.
13. De Backer D, Dubois MJ, Schmartz D, et al. Microcirculatory alterations in cardiac surgery: effects of cardiopulmonary bypass and anesthesia. Ann Thorac Surg, 2009, 88(5): 1396-1403.
14. Martinez A, Seymour C, Nam M. Minute ventilation recovery time: a predictor of extubation outcome. Chest, 2003, 123(4): 1214-1221.
15. 龙小毛, 林辉, 李香伟. 16例心血管病术后消化道出血病因分析. 心肺血管病杂志, 2008, 27(5): 295-296.
16. 石进, 李雅君, 吴素萍. 肠溶阿司匹林与冠心病患者结肠出血:31例临床分析. 胃肠病学, 2008, 13(4): 244-245.
17. Mead J, Folk F. Gastrointestinal bleeding after cardiac surgery. N Engl J Med, 1969, 281(14): 799.
18. 中华医学杂志编委会. 应激性溃疡防治建议. 现代实用医学, 2003, 15(4): 260-261.
19. Søreide K1, Thorsen K, Søreide JA. Strategies to improve the outcome of emergency surgery for perforated peptic ulce. Br J Surg, 2014, 101(1): e51-e64.
20. 周晔, 王建华, 刘冰, 等. 泮托拉唑对体外循环手术患者胃内酸碱度的影响. 心肺血管病杂志, 2010, 29(3): 197-199.
21. 施学进, 沈翠华, 曹坤跃. 老年脑卒中患者医院内获得性肺炎及其相关独立危险因素的分析. 心肺血管病杂志, 2003, 22(1): 33-35.
22. 董力, 石应康, 刘家珍, 等. 体外循环心内直视术后上消化道大出血的处理. 中国胸心血管外科临床杂志, 1996, 2(4): 229-230.
23. Chen CH, Lin HC, Lin HL, et al. Proton pump inhibitor usage and the associated risk of pneumonia in patients with chron- ic kidney disease. J Microbiol Immunol Infect, 2015, 48(4): 390-396.
24. Lazarus B, Chen Y, Wilson FP, et al. Proton pump inhibitor use and the risk of chronic kidney disease. JAMA Intern Med, 2016, 176(2): 238-246.
25. Xie Y, Bowe B, Li T, et al. Proton pump inhibitors and risk of incident CKD and progression to ESRD. J Am Soc Nephrol, 2016, 27(10): 3153-3163.
26. Peng Y L, Luo J C. The benefits and risks of proton pump inhibitor therapy. J Chin Med Assoc, 2016, 79(1): 1-2.
27. Levenstein S, Rosenstock S, J acobsen RK, et al. Psychological stress increases risk for peptic ulcer, regardless of Helicobacter pylori infection or use of nonsteroidal anti-inflammatory drugs. Clin Gastroenterol Hepatol, 2015, 13(3): 498-506.
28. 陈新贵, 许勋良, 段礼兴, 等. 生长抑素及凝血酶在上消化道溃疡出血治疗中的应用及安全性分析. 中国普通外科杂志, 2016, 25(2): 307-310.
29. Cook DJ, Reeve BK, Guyatt GH, et al. Stress ulcer prophylaxis in critically ill patients. JAMA, 1996, 275(4): 308-314.
30. Kuipers EJ, Thijs JC, Festen HP. The prevalence of helicobacter pylori in peptic ulcer disease. Aliment Pharmacol Ther, 1995, 9(Suppl2): 59-69.
31. Halm U, Halm F, Thein D, et al. Helicobacter pylori infection:A risk factor for upper gastrointestinal bleeding after cardiac surgery? Crit Care Med, 2000, 28(1): 110-113.
32. 郭静贤, 景富春, 贺继东, 等. 急性上消化道出血患者幽门螺杆菌感染分析. 中国公共卫生, 2010, 26(9): 1180-1181.
33. Shiba M, Higuchi K, Kadouchi K, et al. Risk factors for bleeding after endoscopic mucosal resection. World J Gastroenterol, 2005, 11(46): 7335-7339.
34. Andersson B, Nilsson J, Brandt J, et al. Gastrointestinal complications after cardiac surgery. Br J Surg, 2005r, 92(3): 326-333.
35. DiSesa VJ. Gastrointestinal bleeding after cardiac surgery: Does describing the disease prescribe the cure? J Thorac Cardiovasc Surg, 2017, 154(1): 189.

Previous Article
Mapping knowledge domains analysis of pancreatic neuroendocrine neoplasm research based on CiteSpace

Chinese Journal of Clinical Thoracic and Cardiovascular Surgery

Research progress on gastrointestinal hemorrhage after cardiac surgery

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Format

Content