WU Yuhao 1,2,4,5 , ZHOU Yuehang 1,2,4,5 , JIN Xin 1,3,4,5 , KUANG Hongyu 2,3,4,5 , LI Yonggang 1,2,4,5 , WU Chun 1,2,4,5
  • 1. Department of Cardiothoracic Surgery, Children’s Hospital of Chongqing Medical University, Chongqing, 400014, P.R.China;
  • 2. Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, 400014, P.R.China;
  • 3. Department of Cardiology, Children’s Hospital of Chongqing Medical University, Chongqing, 400014, P.R.China;
  • 4. China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Chongqing, 400014, P.R.China;
  • 5. Chongqing Key Laboratory of Pediatrics, Chongqing, 400014, P.R.China;
WU Chun, Email: wuchun007@sina.com
Congenital heart disease; coarctation of the aorta; urgery; infants
10.7507/1007-4848.201806060
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Objective  To summarize the clinical characteristics of coarctation of the aorta (CoA) associated with intracardiac anomalies in infants. Methods  The data from August 2009 to August 2017 of 86 infants who were diagnosed with CoA associated with intracardiac anomalies were analyzed. Preoperative diagnosis, surgical findings and post-operation follow-up were analyzed retrospectively. There were 56 males and 30 females at age of 1–346 (95.1±78.0)d. All the included patients underwent single-stage repair of CoA associated with intracardiac anomalies. Results  Mean operative time was 279.0±56.4 min, mean cardiopulmonary bypass time was 162.3±51.0 min, and mean aorta cross-clamp time was 74.7±25.2 min. Mean length of ICU stay and ventilation time was 7.4±4.7 days and 101.1±75.4 hours, respectively. The residual transcoarctation gradient before discharge was lower than pre-operative transcoarctation gradient significantly (42.3±17.7 mm Hg vs. 22.1±9.4 mm Hg, P<0.001), and 7 early deaths were observed after surgery. The mean follow-up time of 79 hospital survivors was 31.0±27.4 months. And no late death was found. Transcoarctation gradient of hospital survivors in the last time follow-up was 21.2±11.0 mm Hg. Transcoarctation gradient of 29 patients was higher than 20 mm Hg. However, only 4 patients with significant clinical symptom of lower limbs retardation were recommended for ballon angioplasty consultant. The cumulative recoarctation-free survival in 2-year follow-up was 69.2%. Conclusions  To avoid early second-stage operations, single-stage repair of CoA associated with intracardiac anomalies is effective and safe, and the outcomes of early to mid term follow-up are satisfactory.