C 臂 CT 引导下微波消融治疗非小细胞肺癌的近期疗效观察_Chinese Journal of Clinical Thoracic and Cardiovascular Surgery

Authors：

薛明 ¹ , 李刚 ¹ ,  郭喜田 ¹ , 梁贵友 ² , 王黙 ³

1. ;
2. ;
3. ;

Corresponding author：

郭喜田, Email: 18660377758@163.com

Keywords：

C 臂 CT; 微波消融; 非小细胞肺癌

DOI：

10.7507/1007-4848.201812027

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目的探讨 C 臂 CT 引导下微波消融治疗非小细胞肺癌的安全性及有效性，总结围术期并发症的危险因素及处理办法。方法回顾性分析 2014 年 10 月至 2016 年 10 月我院46例非小细胞肺癌患者在 C 臂 CT 引导下行微波消融治疗的临床资料，其中男 34 例、女 12 例，年龄 71（44～83）岁。分析无进展生存期、总生存期、围术期并发症。结果 46 例患者实施了微波消融治疗，消融功率 60（45～70）W，消融时间 8（4～15）min。成功率 100.00%，完全消融率 84.91%（45/53），中位随访时间为 14（5～24）个月, 1、2 年生存率为 74.31%、28.36%；中位无进展生存期为 13 个月［95%CI（10.42，15.58）］，中位总生存期为 16 个月［95%CI（13.24，18.76）］。并发症发生率 19.57%（9/46），其中气胸 8.69%（4/46）；不良反应发生率 43.48%（20/46），其中胸痛 30.43%（14/46），围术期无严重并发症。结论 C 臂 CT 引导下经皮微波消融治疗非小细胞肺癌是一种安全、有效的治疗方法，值得推广。

Citation： 薛明, 李刚, 郭喜田, 梁贵友, 王黙. C 臂 CT 引导下微波消融治疗非小细胞肺癌的近期疗效观察. Chinese Journal of Clinical Thoracic and Cardiovascular Surgery, 2019, 26(9): 936-940. doi: 10.7507/1007-4848.201812027 Copy

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5.	李建军, 郑加生, 崔雄伟, 等. CT引导下经皮微波消融治疗肺癌的临床疗效分析. 中华介入放射学电子杂志, 2014, 2(1): 35-37.
6.	Sidoff L, Dupuy DE. Clinical experiences with microwave thermal ablation of lung malignancies. Int J Hyperthermia, 2017, 33(1): 25-33.
7.	Belfiore G, Ronza F, Belfiore MP, et al. Patients' survival in lung malignancies treated by microwave ablation: our experience on 56 patients. Eur J Radiol, 2013, 82(1): 177-181.
8.	Healey TT, March BT, Baird G, et al. Microwave ablation for lung neoplasms: a retrospective analysis of long-term results. J Vasc Interv Radiol, 2017, 28(2): 206-211.
9.	Amouyal G, Pernot S, Déan C, et al. Percutaneous radiofrequency ablation of lung metastases from colorectal carcinoma under C-arm cone beam CT guidance. Diagn Interv Imaging, 2017, 98(11): 793-799.
10.	刘宝东, 叶欣, 范卫军, 等. 影像引导射频消融治疗肺部肿瘤专家共识(2018年版). 中国肺癌杂志, 2018, 21(2): 76-88.
11.	李晓群, 张勇, 黄大钡, 等. C臂CT在15例肺部小病灶射频消融术中的应用. 介入放射学杂志, 2013, 22(1): 67-70.
12.	马勇恩, 马幸生. CT引导下经皮穿刺微波消融治疗原发性肺癌患者39例的临床分析. 中国胸心血管外科临床杂志, 2017, 6(23): 488-490.
13.	Kwan SW, Mortell KE, Talenfeld AD, et al. Thermal ablation matches sublobar resection outcomes in older patients with early-stage non-small cell lung cancer. J Vasc Interv Radiol, 2014, 25(1): 1-9.
14.	李记华. C臂CT在胸部介入诊疗中的应用现状. 中国介入影像与治疗学, 2012, 9(4): 307-310.

1. Bray F, Ferlay J, Soerjomataram I, et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin, 2018, 68(6): 394-424.
2. Chen W, Zheng R, Baade PD, et al. Cancer statistics in China, 2015. CA Cancer J Clin, 2016, 66(2): 115-132.
3. Gobara H, Arai Y, Kobayashi T, et al. Percutaneous radiofrequency ablation for patients with malignant lung tumors: a phase II prospective multicenter study (JIVROSG-0702). Jpn J Radiol, 2016, 34(8): 556-563.
4. Du S, Qin D, Pang R, et al. Long-term efficacy of radiofrequency ablation combined with chemotherapy in the treatment of patients with advanced non-small Cell Lung Cancer--a retrospective study. Zhongguo Fei Ai Za Zhi, 2017, 20(10): 675-682.
5. 李建军, 郑加生, 崔雄伟, 等. CT引导下经皮微波消融治疗肺癌的临床疗效分析. 中华介入放射学电子杂志, 2014, 2(1): 35-37.
6. Sidoff L, Dupuy DE. Clinical experiences with microwave thermal ablation of lung malignancies. Int J Hyperthermia, 2017, 33(1): 25-33.
7. Belfiore G, Ronza F, Belfiore MP, et al. Patients' survival in lung malignancies treated by microwave ablation: our experience on 56 patients. Eur J Radiol, 2013, 82(1): 177-181.
8. Healey TT, March BT, Baird G, et al. Microwave ablation for lung neoplasms: a retrospective analysis of long-term results. J Vasc Interv Radiol, 2017, 28(2): 206-211.
9. Amouyal G, Pernot S, Déan C, et al. Percutaneous radiofrequency ablation of lung metastases from colorectal carcinoma under C-arm cone beam CT guidance. Diagn Interv Imaging, 2017, 98(11): 793-799.
10. 刘宝东, 叶欣, 范卫军, 等. 影像引导射频消融治疗肺部肿瘤专家共识(2018年版). 中国肺癌杂志, 2018, 21(2): 76-88.
11. 李晓群, 张勇, 黄大钡, 等. C臂CT在15例肺部小病灶射频消融术中的应用. 介入放射学杂志, 2013, 22(1): 67-70.
12. 马勇恩, 马幸生. CT引导下经皮穿刺微波消融治疗原发性肺癌患者39例的临床分析. 中国胸心血管外科临床杂志, 2017, 6(23): 488-490.
13. Kwan SW, Mortell KE, Talenfeld AD, et al. Thermal ablation matches sublobar resection outcomes in older patients with early-stage non-small cell lung cancer. J Vasc Interv Radiol, 2014, 25(1): 1-9.
14. 李记华. C臂CT在胸部介入诊疗中的应用现状. 中国介入影像与治疗学, 2012, 9(4): 307-310.

Chinese Journal of Clinical Thoracic and Cardiovascular Surgery

C 臂 CT 引导下微波消融治疗非小细胞肺癌的近期疗效观察

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