Investigation of mid-to-long term quality of life and influencing factors in patients after heart valve replacement_Chinese Journal of Clinical Thoracic and Cardiovascular Surgery

Authors：

TAN Wei ¹ , ZHENG Ping ^1,2 ,  GONG Renrong ^1,3

1. West China School of Nursing, Sichuan University/West China Hospital, Sichuan University, Chengdu, 610041, P. R. China;
2. Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, 610041, P. R. China;
3. Department of Surgery, West China Hospital, Sichuan University, Chengdu, 610041, P. R. China;

Corresponding author：

GONG Renrong, Email: gongrenrong@wchscu.cn

Keywords：

Heart valve replacement; mid-to-long term; quality of life; influencing factor

DOI：

10.7507/1007-4848.202012016

Video：

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Objective To investigate the mid-to-long term quality of life (QOL) and influencing factors in the patients after heart valve replacement.Methods Convenient sampling method was used to recruit 224 patients who had heart valve replacement surgery in our hospital from June 2008 to June 2017. There were 63 males and 161 females, aged 18-83 (51.49±10.60) years. General information questionnaire and MOS SF-36 scale were used to collect data. Univariate analysis and multiple linear regression analysis were used to analyze and determine the influencing factors for the QOL.Results The total score of QOL of 224 patients was 71.78±17.60 points. All these scores of the patients were significantly lower than those of the general population of Chengdu (P<0.05) except the dimension of vitality. The QOL scores differences between sex, marital status, family income, working condition, the occurrence of anticoagulant complications and other complications were significant (P<0.05). Multivariate analysis showed that family income, working condition, the occurrence of anticoagulant complications and other complications could be included in the regression model, explaining 26.8% of total variance. Conclusion The mid-to-long term QOL is lower in the patients after heart valve replacement. Family income, working condition, anticoagulant complications and other complications are the main influencing factors for mid-to-long term QOL for patients after heart valve replacement.

Citation： TAN Wei, ZHENG Ping, GONG Renrong. Investigation of mid-to-long term quality of life and influencing factors in patients after heart valve replacement. Chinese Journal of Clinical Thoracic and Cardiovascular Surgery, 2022, 29(8): 1003-1007. doi: 10.7507/1007-4848.202012016 Copy

1.	中国心血管健康与疾病报告编写组. 中国心血管健康与疾病报告2019概要. 心脑血管病防治, 2020, 20(5): 437-450.
2.	Ciuca C, Fortuna D, Ferrari S, et al. Cognitive and quality of life trajectory after either surgical or transcatheter aortic valve replacement in high-risk patients. G Ital Cardiol (Rome), 2016, 17(12 Suppl 1): 15S-21S.
3.	Tsang FH, Wong SJ, Cheung YF. Pulmonary valve replacement and quality-of-life assessment. Asian Cardiovasc Thorac Ann, 2016, 24(1): 5-11.
4.	Coelho P, Ferreira LN, Vital C, et al. Does aortic valve replacement surgery improve patients' quality of life? Acta Med Port, 2018, 31(7-8): 399-408.
5.	Jansen Klomp WW, Nierich AP, Peelen LM, et al. Survival and quality of life after surgical aortic valve replacement in octogenarians. J Cardiothorac Surg, 2016, 11: 38.
6.	Korteland NM, Top D, Borsboom GJ, et al. Quality of life and prosthetic aortic valve selection in non-elderly adult patients. Interact Cardiovasc Thorac Surg, 2016, 22(6): 723-728.
7.	Huygens SA, van der Kley F, Bekkers JA, et al. Beyond the clinical impact of aortic and pulmonary valve implantation: Health-related quality of life, informal care and productivity. Eur J Cardiothorac Surg, 2019, 55(4): 751-759.
8.	赵龙超, 杨展, 胡晓, 等. SF-12v2与SF-36v2在成都市居民人群中的等效性评价. 四川大学学报(医学版), 2018, 49(1): 87-92.
9.	刘朝杰, 李宁秀, 任晓晖, 等. 36条目简明量表在中国人群中的适用性研究. 华西医科大学学报, 2001, 32(1): 39-42.
10.	Taillefer MC, Dupuis G, Hardy JF, et al. Quality of life before and after heart valve surgery is influenced by gender and type of valve. Qual Life Res, 2005, 14(3): 769-778.
11.	Bäz L, Wiesel M, Möbius-Winkler S, et al. Depression and anxiety in elderly patients with severe symptomatic aortic stenosis persistently improves after transcatheter aortic valve replacement (TAVR). Int J Cardiol, 2020, 309: 48-54.
12.	吴丽仙, 丁巧玲, 李艳, 等. 心脏瓣膜置换术后患者生活质量与社会支持的相关性研究. 丽水学院学报, 2017, 39(2): 82-85.
13.	温雅, 蒋晓莲, 白阳静, 等. 心脏瓣膜置换术后患者生存质量研究现状. 华西医学, 2016, 31(6): 1137-1141.
14.	Wang X, Xu B, Liang H, et al. Distribution characteristics and factors influencing oral warfarin adherence in patients after heart valve replacement. Patient Prefer Adherence, 2018, 12: 1641-1648.
15.	Pragt H, Pieper PG, van Slooten YJ, et al. Quality of life among patients with congenital heart disease after valve replacement. Semin Thorac Cardiovasc Surg, Autumn, 2019, 31(3): 549-558.
16.	于秋霞. 心脏瓣膜置换术后症状困扰与生活质量的关系. 护理实践与研究, 2020, 17(17): 43-45.
17.	Arnold SV, Zhang Y, Baron SJ, et al. Impact of short-term complications on mortality and quality of life after transcatheter aortic valve replacement. JACC Cardiovasc Interv, 2019, 12(4): 362-369.
18.	Taghadosi M, Memarian R, Ahmadi F. The experiences of "difficult life" in heart valve replaced patients. Iran Red Crescent Med J, 2014, 16(8): e19147.
19.	Kottmaier M, Hettich I, Deutsch MA, et al. Quality of life and anxiety in younger patients after biological versus mechanical aortic valve replacement. Thorac Cardiovasc Surg, 2017, 65(3): 198-205.
20.	栗林, 王学宁, 郭万鹏, 等. 微信平台对心脏瓣膜置换术后出院患者口服华法林延续护理的效果. 中国药物与临床, 2017, 17(8): 1252-1254.
21.	盛卫勇, 晁阳阳, 赵国昌, 等. 二尖瓣置换术患者术后生存质量分析. 河南医学研究, 2018, 27(23): 4260-4262.

1. 中国心血管健康与疾病报告编写组. 中国心血管健康与疾病报告2019概要. 心脑血管病防治, 2020, 20(5): 437-450.
2. Ciuca C, Fortuna D, Ferrari S, et al. Cognitive and quality of life trajectory after either surgical or transcatheter aortic valve replacement in high-risk patients. G Ital Cardiol (Rome), 2016, 17(12 Suppl 1): 15S-21S.
3. Tsang FH, Wong SJ, Cheung YF. Pulmonary valve replacement and quality-of-life assessment. Asian Cardiovasc Thorac Ann, 2016, 24(1): 5-11.
4. Coelho P, Ferreira LN, Vital C, et al. Does aortic valve replacement surgery improve patients' quality of life? Acta Med Port, 2018, 31(7-8): 399-408.
5. Jansen Klomp WW, Nierich AP, Peelen LM, et al. Survival and quality of life after surgical aortic valve replacement in octogenarians. J Cardiothorac Surg, 2016, 11: 38.
6. Korteland NM, Top D, Borsboom GJ, et al. Quality of life and prosthetic aortic valve selection in non-elderly adult patients. Interact Cardiovasc Thorac Surg, 2016, 22(6): 723-728.
7. Huygens SA, van der Kley F, Bekkers JA, et al. Beyond the clinical impact of aortic and pulmonary valve implantation: Health-related quality of life, informal care and productivity. Eur J Cardiothorac Surg, 2019, 55(4): 751-759.
8. 赵龙超, 杨展, 胡晓, 等. SF-12v2与SF-36v2在成都市居民人群中的等效性评价. 四川大学学报(医学版), 2018, 49(1): 87-92.
9. 刘朝杰, 李宁秀, 任晓晖, 等. 36条目简明量表在中国人群中的适用性研究. 华西医科大学学报, 2001, 32(1): 39-42.
10. Taillefer MC, Dupuis G, Hardy JF, et al. Quality of life before and after heart valve surgery is influenced by gender and type of valve. Qual Life Res, 2005, 14(3): 769-778.
11. Bäz L, Wiesel M, Möbius-Winkler S, et al. Depression and anxiety in elderly patients with severe symptomatic aortic stenosis persistently improves after transcatheter aortic valve replacement (TAVR). Int J Cardiol, 2020, 309: 48-54.
12. 吴丽仙, 丁巧玲, 李艳, 等. 心脏瓣膜置换术后患者生活质量与社会支持的相关性研究. 丽水学院学报, 2017, 39(2): 82-85.
13. 温雅, 蒋晓莲, 白阳静, 等. 心脏瓣膜置换术后患者生存质量研究现状. 华西医学, 2016, 31(6): 1137-1141.
14. Wang X, Xu B, Liang H, et al. Distribution characteristics and factors influencing oral warfarin adherence in patients after heart valve replacement. Patient Prefer Adherence, 2018, 12: 1641-1648.
15. Pragt H, Pieper PG, van Slooten YJ, et al. Quality of life among patients with congenital heart disease after valve replacement. Semin Thorac Cardiovasc Surg, Autumn, 2019, 31(3): 549-558.
16. 于秋霞. 心脏瓣膜置换术后症状困扰与生活质量的关系. 护理实践与研究, 2020, 17(17): 43-45.
17. Arnold SV, Zhang Y, Baron SJ, et al. Impact of short-term complications on mortality and quality of life after transcatheter aortic valve replacement. JACC Cardiovasc Interv, 2019, 12(4): 362-369.
18. Taghadosi M, Memarian R, Ahmadi F. The experiences of "difficult life" in heart valve replaced patients. Iran Red Crescent Med J, 2014, 16(8): e19147.
19. Kottmaier M, Hettich I, Deutsch MA, et al. Quality of life and anxiety in younger patients after biological versus mechanical aortic valve replacement. Thorac Cardiovasc Surg, 2017, 65(3): 198-205.
20. 栗林, 王学宁, 郭万鹏, 等. 微信平台对心脏瓣膜置换术后出院患者口服华法林延续护理的效果. 中国药物与临床, 2017, 17(8): 1252-1254.
21. 盛卫勇, 晁阳阳, 赵国昌, 等. 二尖瓣置换术患者术后生存质量分析. 河南医学研究, 2018, 27(23): 4260-4262.

Chinese Journal of Clinical Thoracic and Cardiovascular Surgery

Investigation of mid-to-long term quality of life and influencing factors in patients after heart valve replacement

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