Mitral regurgitation (MR) is the most common heart valve disease. In recent years, the rise of interventional therapy has expanded the indications of interventional treatment for patients with MR, but the epidemiological characteristics of MR (especially the number of patients with MR requiring treatment) in China are still unclear. In this paper, we analyzed and estimated the number of MR patients in China based on three epidemiological studies in Europe and America, and referring to the patients population surveys from Zhongshan Hospital Affiliated to Fudan University, the Second Affiliated Hospital Zhejiang University School of Medicine and Beijing Fuwai Hospital. Our analysis estimated that about 7.5 million patients with MR need intervention in China, including about 5.5 million patients with severe MR.
Citation：
PAN Wenzhi, ZHOU Daxin, GE Junbo. Estimation of the number of patients with mitral regurgitation in China. Chinese Journal of Clinical Thoracic and Cardiovascular Surgery, 2021, 28(5): 495-498. doi: 10.7507/1007-4848.202012080
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Copyright © the editorial department of Chinese Journal of Clinical Thoracic and Cardiovascular Surgery of West China Medical Publisher. All rights reserved
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Writing Committee Members, Otto CM, Nishimura RA, et al. 2020 ACC/AHA guideline for the management of patients with valvular heart disease: Executive summary: A report of the American College of Cardiology/American Heart Association Joint Committee on clinical practice guidelines. J Am Coll Cardiol. 2020. [Epub ahead of print].
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Dziadzko V, Clavel MA, Dziadzko M, et al. Outcome and undertreatment of mitral regurgitation: A community cohort study. Lancet, 2018, 391(10124): 960-969.
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d'Arcy JL, Coffey S, Loudon MA, et al. Large-scale community echocardiographic screening reveals a major burden of undiagnosed valvular heart disease in older people: The OxVALVE population cohort study. Eur Heart J, 2016, 37(47): 3515-3522.
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Li J, Pan W, Yin Y, et al. Prevalence and correlates of mitral regurgitation in the current era: An echocardiography study of a Chinese patient population. Acta Cardiol, 2016, 71(1): 55-60.
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Hu P, Liu XB, Liang J, et al. A hospital-based survey of patients with severe valvular heart disease in China. Int J Cardiol, 2017, 231: 244-247.
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Zhang B, Xu H, Zhang H, et al. Prognostic value of N-terminal pro-B-type natriuretic peptide in elderly patients with valvular heart disease. J Am Coll Cardiol, 2020, 75(14): 1659-1672.
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Head SJ, van Leeuwen WJ, Van Mieghem NM, et al. Surgical or transcatheter mitral valve intervention: Complex disease requires complex decisions. EuroIntervention, 2014, 9(10): 1133-1135.
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- 1. Writing Committee Members, Otto CM, Nishimura RA, et al. 2020 ACC/AHA guideline for the management of patients with valvular heart disease: Executive summary: A report of the American College of Cardiology/American Heart Association Joint Committee on clinical practice guidelines. J Am Coll Cardiol. 2020. [Epub ahead of print].
- 2. Nkomo VT, Gardin JM, Skelton TN, et al. Burden of valvular heart diseases: A population-based study. Lancet, 2006, 368(9540): 1005-1011.
- 3. Dziadzko V, Clavel MA, Dziadzko M, et al. Outcome and undertreatment of mitral regurgitation: A community cohort study. Lancet, 2018, 391(10124): 960-969.
- 4. d'Arcy JL, Coffey S, Loudon MA, et al. Large-scale community echocardiographic screening reveals a major burden of undiagnosed valvular heart disease in older people: The OxVALVE population cohort study. Eur Heart J, 2016, 37(47): 3515-3522.
- 5. Li J, Pan W, Yin Y, et al. Prevalence and correlates of mitral regurgitation in the current era: An echocardiography study of a Chinese patient population. Acta Cardiol, 2016, 71(1): 55-60.
- 6. Hu P, Liu XB, Liang J, et al. A hospital-based survey of patients with severe valvular heart disease in China. Int J Cardiol, 2017, 231: 244-247.
- 7. Zhang B, Xu H, Zhang H, et al. Prognostic value of N-terminal pro-B-type natriuretic peptide in elderly patients with valvular heart disease. J Am Coll Cardiol, 2020, 75(14): 1659-1672.
- 8. Head SJ, van Leeuwen WJ, Van Mieghem NM, et al. Surgical or transcatheter mitral valve intervention: Complex disease requires complex decisions. EuroIntervention, 2014, 9(10): 1133-1135.
