Transapical transcatheter aortic valve replacement using Ken-Valve for pure severe aortic regurgitation: A case report_Chinese Journal of Clinical Thoracic and Cardiovascular Surgery

Authors：

LIU Lulu , KANG Zhefeng , XIAO Bowen , SHI Jun , WU Binggang , ZHU Xingyu ,  GUO Yingqiang

Department of Cardiovascular Surgery, West China Hospital, Sichuan University, Chengdu, 610041, P. R. China;

Corresponding author：

GUO Yingqiang, Email: drguoyq@hotmail.com

Keywords：

Pure aortic regurgitation; transcatheter aortic valve replacement; Ken-Valve prostheses; transapical

DOI：

10.7507/1007-4848.202108018

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Transcatheter aortic valve replacement (TAVR) has become the preferred treatment for severe aortic stenosis. The localization and anchor of many transcatheter heart valves available in the clinic today are dependent on the calcific aortic valve leaflet of patients. We reported here a successful case of transapical aortic valve implantation with Ken-Valve heart valve in an 82-year-old male patient with pure severe aortic regurgitation without native valve calcium. Postoperative follow-up (3 months after the surgery) showed that the cardiac function significantly improved. The echocardiography indicated that the Ken-Valve prosthesis worked well without perivalvular regurgitation. The short-term clinical effect was satisfactory. The Ken-Valve with three position anchors is proved to be suitable for the treatment of pure aortic regurgitation.

Citation： LIU Lulu, KANG Zhefeng, XIAO Bowen, SHI Jun, WU Binggang, ZHU Xingyu, GUO Yingqiang. Transapical transcatheter aortic valve replacement using Ken-Valve for pure severe aortic regurgitation: A case report. Chinese Journal of Clinical Thoracic and Cardiovascular Surgery, 2022, 29(8): 1078-1082. doi: 10.7507/1007-4848.202108018 Copy

1.	Liu L, Chen S, Shi J, et al. Transcatheter aortic valve replacement in aortic regurgitation. Ann Thorac Surg, 2020, 110(6):1959-1965.
2.	Silaschi M, Conradi L, Wendler O, et al. The JUPITER registry: One-year outcomes of transapical aortic valve implantation using a second generation transcatheter heart valve for aortic regurgitation. Catheter Cardiovasc Interv, 2018, 91(7): 1345-1351.
3.	Smith CR, Leon MB, Mack MJ, et al. Transcatheter versus surgical aortic-valve replacement in high-risk patients. N Engl J Med, 2011, 364(23): 2187-2198.
4.	Adams DH, Popma JJ, Reardon MJ, et al. Transcatheter aortic-valve replacement with a self-expanding prosthesis. N Engl J Med, 2014, 370(19): 1790-1798.
5.	Otto CM, Nishimura RA, Bonow RO, et al. 2020 ACC/AHA guideline for the management of patients with valvular heart disease: Executive summary: A report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. J Am Coll Cardiol, 2021, 77(4): 450-500.
6.	中华医学会心血管病学分会结构性心脏病学组. 经导管主动脉瓣置换术治疗二叶式主动脉瓣狭窄的中国专家建议. 中华心血管病杂志, 2020, 48(8): 634-640.
7.	Roy DA, Schaefer U, Guetta V, et al. Transcatheter aortic valve implantation for pure severe native aortic valve regurgitation. J Am Coll Cardiol, 2013, 61(15): 1577-1584.
8.	De Backer O, Pilgrim T, Simonato M, et al. Usefulness of transcatheter aortic valve implantation for treatment of pure native aortic valve regurgitation. Am J Cardiol, 2018, 122(6): 1028-1035.
9.	Maganti K, Rigolin VH, Sarano ME, et al. Valvular heart disease: diagnosis and management. Mayo Clin Proc, 2010, 85(5): 483-500.
10.	Wernly B, Eder S, Navarese EP, et al. Transcatheter aortic valve replacement for pure aortic valve regurgitation: "On-label" versus "off-label" use of TAVR devices. Clin Res Cardiol, 2019, 108(8): 921-930.
11.	Liu L, Zhang J, Peng Y, et al. Learning curve for transcatheter aortic valve replacement for native aortic regurgitation: Safety and technical performance study. Clin Cardiol, 2020, 43(5): 475-482.
12.	Sawaya FJ, Deutsch MA, Seiffert M, et al. Safety and Efficacy of transcatheter aortic valve replacement in the treatment of pure aortic regurgitation in native valves and failing surgical bioprostheses: Results from an international registry study. JACC Cardiovasc Interv, 2017, 10(10): 1048-1056.
13.	Purita PAM, Tahoces LS, Fraccaro C, et al. Transcatheter treatment of native aortic valve regurgitation: Results from an international registry using the transfemoral ACURATE neo valve. Int J Cardiol Heart Vasc, 2020, 27: 100480.
14.	Praz F, Windecker S, Huber C, et al. Expanding indications of transcatheter heart valve interventions. JACC Cardiovasc Interv, 2015, 8(14): 1777-1796.

1. Liu L, Chen S, Shi J, et al. Transcatheter aortic valve replacement in aortic regurgitation. Ann Thorac Surg, 2020, 110(6):1959-1965.
2. Silaschi M, Conradi L, Wendler O, et al. The JUPITER registry: One-year outcomes of transapical aortic valve implantation using a second generation transcatheter heart valve for aortic regurgitation. Catheter Cardiovasc Interv, 2018, 91(7): 1345-1351.
3. Smith CR, Leon MB, Mack MJ, et al. Transcatheter versus surgical aortic-valve replacement in high-risk patients. N Engl J Med, 2011, 364(23): 2187-2198.
4. Adams DH, Popma JJ, Reardon MJ, et al. Transcatheter aortic-valve replacement with a self-expanding prosthesis. N Engl J Med, 2014, 370(19): 1790-1798.
5. Otto CM, Nishimura RA, Bonow RO, et al. 2020 ACC/AHA guideline for the management of patients with valvular heart disease: Executive summary: A report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. J Am Coll Cardiol, 2021, 77(4): 450-500.
6. 中华医学会心血管病学分会结构性心脏病学组. 经导管主动脉瓣置换术治疗二叶式主动脉瓣狭窄的中国专家建议. 中华心血管病杂志, 2020, 48(8): 634-640.
7. Roy DA, Schaefer U, Guetta V, et al. Transcatheter aortic valve implantation for pure severe native aortic valve regurgitation. J Am Coll Cardiol, 2013, 61(15): 1577-1584.
8. De Backer O, Pilgrim T, Simonato M, et al. Usefulness of transcatheter aortic valve implantation for treatment of pure native aortic valve regurgitation. Am J Cardiol, 2018, 122(6): 1028-1035.
9. Maganti K, Rigolin VH, Sarano ME, et al. Valvular heart disease: diagnosis and management. Mayo Clin Proc, 2010, 85(5): 483-500.
10. Wernly B, Eder S, Navarese EP, et al. Transcatheter aortic valve replacement for pure aortic valve regurgitation: "On-label" versus "off-label" use of TAVR devices. Clin Res Cardiol, 2019, 108(8): 921-930.
11. Liu L, Zhang J, Peng Y, et al. Learning curve for transcatheter aortic valve replacement for native aortic regurgitation: Safety and technical performance study. Clin Cardiol, 2020, 43(5): 475-482.
12. Sawaya FJ, Deutsch MA, Seiffert M, et al. Safety and Efficacy of transcatheter aortic valve replacement in the treatment of pure aortic regurgitation in native valves and failing surgical bioprostheses: Results from an international registry study. JACC Cardiovasc Interv, 2017, 10(10): 1048-1056.
13. Purita PAM, Tahoces LS, Fraccaro C, et al. Transcatheter treatment of native aortic valve regurgitation: Results from an international registry using the transfemoral ACURATE neo valve. Int J Cardiol Heart Vasc, 2020, 27: 100480.
14. Praz F, Windecker S, Huber C, et al. Expanding indications of transcatheter heart valve interventions. JACC Cardiovasc Interv, 2015, 8(14): 1777-1796.

Chinese Journal of Clinical Thoracic and Cardiovascular Surgery

Transapical transcatheter aortic valve replacement using Ken-Valve for pure severe aortic regurgitation: A case report

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