LIU Yixian 1,2 , ZHENG Li 1,2
  • 1. Clinical Trial Center, West China Hospital, Sichuan University, Chengdu, 610041, P. R. China;
  • 2. NMPA Key Laboratory for Clinical Research and Evaluation of Innovative Drug, West China Hospital, Sichuan University, Chengdu, 610041, P. R. China;
ZHENG Li, Email: zhengli@wchscu.cn
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Virtual clinical trials are clinical trials conducted through computer simulation technology, which breaks through the limitations of traditional clinical trials and has the advantages of saving time, reducing costs, and reducing the risk of human trials. With the application of new computer technologies such as population pharmacokinetics, physiologically-based pharmacokinetics, quantitative systems pharmacology, and artificial intelligence, the field of virtual clinical trials in healthcare has become an important development direction. This article will give a preliminary review of the connotation, methods and future development trends of virtual clinical trials, aiming to provide reference for the application of new technologies and methods in clinical trials.

Citation: LIU Yixian, ZHENG Li. Application status and development trend of virtual clinical trials. Chinese Journal of Clinical Thoracic and Cardiovascular Surgery, 2024, 31(2): 216-222. doi: 10.7507/1007-4848.202311059 Copy