• Department of General Surgery, The Second Artillery General Hospital PLA, Beijing 100088, China;
DONGMao-sheng, Email: 13051186112@163.com
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Objective To summarize the research progress of preoperative regional-arterial chemotherapy in advanced gastric cancer. Method The literatures about the research progress of preoperative regional-arterial chemotherapy in the advanced gastric cancer were reviewed. Results The preoperative regional-arterial chemotherapy in the advanced gastric cancer could decrease the tumour stage, improve the R0 resection rate and the long-term survival rate, effectively improve the drug concentrations of tumor and portal vein, and not only kill or damage cancer cells directly, but also prevent the metastasis of liver and lymph nodes effectively, and reduce the side effects, cause the nuclear pyknosis and fracture of cancer cells in a short time. The course of preoperative regional-arterial chemotherapy in the advanced gastric cancer generally was 4-9 weeks, and then whether the surgery treatment was decided to undergo according to the results of the curative effect evaluation. Conclusions The preoperative regional-arterial chemotherapy in the advanced gastric cancer has more advantages than intravenous chemotherapy, further research of multicenter and large clinical trials, would inaugurate a wider application prospects.

Citation: LIZhen-kai, DONGMao-sheng. Research Progress of Preoperative Regional-arterial Chemotherapy in Advanced Gastric Cancer. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2015, 22(11): 1410-1415. doi: 10.7507/1007-9424.20150369 Copy

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