Research progress of residual nodules after thermal ablation for benign thyroid nodules_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Authors：

 YE Liang , SUN Ke , ZHANG Chao , LIU Xiping , LI Zhidong , XU Shaozhong

The First Department of General Surgery, Zhuzhou Central Hospital, Zhuzhou, Hunan 412000, P. R. China;

Corresponding author：

YE Liang, Email: 281737368@qq.com

Keywords：

benign nodule of thyroid; thermal ablation; review

DOI：

10.7507/1007-9424.201904049

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

Objective To investigate the research progress of residual nodules after thermal ablation for benign thyroid nodules.Methods The domestic and foreign guidelines and consensus on the treatment of benign thyroid nodules were collected, and the indications for thermal ablation were summarized. The causes of residual nodules after ablation were analyzed, the characteristics of residual nodules were evaluated through multiple approaches, and the follow-up treatment measures were summarized.Results The indications of thermal ablation of benign thyroid nodules were different at home and abroad. The causes of residual nodules included slow absorption after ablation and incomplete ablation. Among the evaluation methods of residual nodules, the nodules volume reduction rate was the evaluation standard of short-term efficacy, contrast-enhanced ultrasound was the best method, color Doppler blood color distributionwas the most commonly used method, elastic imaging was a valuable method, and puncture pathology biopsy was an important standard. Reablation and surgical resection were the follow-up treatments for residual nodules.Conclusions As a new technique, thermal ablation of benign thyroid nodules has some advantages, but it is flooding at present. In the future, it is necessary to standardize indications, improve the efficiency of first ablation, attach importance to pathological complete ablation, and reasonably evaluate the treatment of residual nodules, so that thermal ablation of benign thyroid nodules could reflect rationality, safety, and efficiency, and give full play to its advantages, so as to serve patients better and have better application prospects.

Citation： YE Liang, SUN Ke, ZHANG Chao, LIU Xiping, LI Zhidong, XU Shaozhong. Research progress of residual nodules after thermal ablation for benign thyroid nodules. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2019, 26(11): 1361-1366. doi: 10.7507/1007-9424.201904049 Copy

1.	金鑫荔, 卢伟. 甲状腺结节射频及微波消融治疗—现状及存在问题. 临床放射学杂志, 2017, 36(2): 295-297.
2.	吴震中, 章建全. 甲状腺结节微波热消融治疗的临床进展. 中国介入影像与治疗学, 2016, 13(12): 772-774.
3.	中华医学会内分泌学分会, 中华医学会外科学分会, 中国抗癌协会头颈肿瘤专业委员会, 等. 甲状腺结节和分化型甲状腺癌诊治指南. 中国肿瘤临床, 2012, 39(17): 1249-1272.
4.	Haugen BR, Alexander EK, Bible KC, et al. 2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer. Thyroid, 2016, 26(1): 1-133.
5.	方建强, 赵维安, 李庆. 超声引导微波消融术治疗甲状腺良性结节的疗效与安全性分析. 中国临床医学影像杂志, 2019, 30(4): 250-252, 266.
6.	胡云飞, 蔡雨, 赵胜. 超声介导微波消融术与传统开放手术比较治疗甲状腺良性结节疗效的系统评价. 中国循证医学杂志, 2019, 19(3): 338-347.
7.	Baek JH, Na DG, Lee JH, et al. Korean society of thyroid radiology recommendations for radiofrequency ablation of thyroid nodules. Korean Society of Thyroid Radiology, 2009. [2016-06-01]. http://thyroidimaging.kr/.
8.	Na DG, Lee JH, Jung SL, et al. Radiofrequency ablation of benign thyroid nodules and recurrent thyroid cancers: consensus statement and recommendations. Korean J Radiol, 2012, 13(2): 117-125.
9.	Kim JH, Baek JH, Lim HK, et al. 2017 Thyroid Radiofrequency Ablation Guideline: Korean Society of Thyroid Radiology. Korean J Radiol, 2018, 19(4): 632-655.
10.	Garberoglio R, Aliberti C, Appetecchia M, et al. Radiofrequency ablation for thyroid nodules: which indications? The first Italian opinion statement. J Ultrasound, 2015, 18(4): 423-430.
11.	刁畅, 程若川. 消融治疗在甲状腺结节治疗中的误区与思考. 医学与哲学, 2015, 36(20): 16-21.
12.	浙江省抗癌协会甲状腺肿瘤专业委员会. 甲状腺良性结节、微小癌及颈部转移性淋巴结热消融治疗浙江省专家共识 (2015版). 中国普通外科杂志, 2016, 25(7): 944-946.
13.	中国医师协会甲状腺肿瘤消融治疗技术专家组, 中国抗癌协会甲状腺癌专业委员会, 中国医师协会介入医师分会超声介入专业委员会, 等. 甲状腺良性结节、微小癌及颈部转移性淋巴结热消融治疗专家共识 (2018版). 中国肿瘤, 2018, 27(10): 768-773.
14.	王宇思. 超声引导下经皮微波消融术在甲状腺良性结节治疗中的应用效果观察. 中国疗养医学, 2018, 27(6): 611-612.
15.	苏鸿辉, 吴玉帆, 陈耿臻. 超声引导下经皮微波消融治疗甲状腺良性结节的并发症. 现代医院, 2017, 17(1): 95-98.
16.	张波, 高琼, 李小毅, 等. 甲状腺结节射频消融的历史、现状及展望. 重庆医科大学学报, 2018, 43(12): 1537-1541.
17.	Jung SL, Baek JH, Lee JH, et al. Efficacy and safety of radiofrequency ablation for benign thyroid nodules: a prospective multicenter study. Korean J Radiol, 2018, 19(1): 167-174.
18.	Liu YJ, Qian LX, Liu D, et al. Ultrasound-guided microwave ablation in the treatment of benign thyroid nodules in 435 patients. Exp Biol Med (Maywood), 2017, 242(15): 1515-1523.
19.	Sartori S, Mauri G, Tombesi P, et al. Ultrasound-guided percutaneous laser ablation is safe and effective in the treatment of small renal tumors in patients at increased bleeding risk. Int J Hyperthermia, 2018, 35(1): 19-25.
20.	Mauri G, Nicosia L, Della Vigna P, et al. Percutaneous laser ablation for benign and malignant thyroid diseases. Ultrasonography, 2019, 38(1): 25-36.
21.	Lim HK, Lee JH, Ha EJ, et al. Radiofrequency ablation of benign non-functioning thyroid nodules: 4-year follow-up results for 111 patients. Eur Radiol, 2013, 23(4): 1044-1049.
22.	Valcavi R, Riganti F, Bertani A, et al. Percutaneous laser ablation of cold benign thyroid nodules: a 3-year follow-up study in 122 patients. Thyroid, 2010, 20(11): 1253-1261.
23.	刘玉辉, 王文玲, 王毅, 等. 超声引导下经皮微波消融甲状腺术后复发结节的临床研究. 临床耳鼻咽喉头颈外科杂志, 2015, 29(7): 622-624.
24.	闫磊, 章建全, 陈红琼, 等. 甲状腺结节微波消融治疗后6个月消融区细胞活性的酶组织化学检测. 第二军医大学学报, 2019, 40(1): 20-24.
25.	Rahal Junior A, Falsarella PM, Mendes GF, et al. Percutaneous laser ablation of benign thyroid nodules: a one year follow-up study. Einstein (Sao Paulo), 2018, 16(4): eAO4279.
26.	马树花, 周平. 超声引导下热消融治疗甲状腺结节的应用. 中外医学研究, 2014, 12(13): 146-147, 148.
27.	郝少龙, 马纪红, 姜立新, 等. 热消融术在甲状腺结节微创治疗中的应用进展. 中华普通外科学文献: 电子版, 2016, 10(1): 77-80.
28.	章建全. 甲状腺结节经皮射频、微波消融治疗指南. 中国医刊, 2014, 49: 90-96.
29.	Lee CU, Kim SJ, Sung JY, et al. Needle track tumor seeding after radiofrequency ablation of a thyroid tumor. Jpn J Radiol, 2014, 32(11): 661-663.
30.	张恒. 甲状腺结节射频消融治疗的效果探析. 中国医药指南, 2015, 13(17): 279-280.
31.	李建如, 罗渝昆. 射频消融技术在甲状腺结节治疗中的应用. 解放军医学院学报, 2016, 37(7): 807-809.
32.	纪莉, 吴凤林, 娄雪峰, 等. 超声弹性成像评估甲状腺良性结节射频消融效果的价值探讨. 中国超声医学杂志, 2014, 30(12): 1071-1073.
33.	刁宗平, 章建全, 盛建国, 等. 超声弹性成像在甲状腺良性结节射频消融中的应用价值及相关动态分析. 第二军医大学学报, 2017, 38(7): 947-950.
34.	孔月, 程志刚, 韩治宇, 等. 组织弹性定量分析在甲状腺良性病灶微波消融治疗中的应用价值. 中国超声医学杂志, 2014, 30(6): 489-492.
35.	Huh JY, Baek JH, Choi H, et al. Symptomatic benign thyroid nodules: efficacy of additional radiofrequency ablation treatment session—prospective randomized study. Radiology, 2012, 263(3): 909-916.
36.	董文武, 张浩, 张平, 等. 甲状腺乳头状癌射频消融治疗后再手术5例临床分析. 中国实用外科杂志, 2015, 35(6): 653-655.
37.	杨映弘, 颜璟, 吴艳军, 等. 液体隔离带法与杠杆撬离法在超声引导下甲状腺微波消融术中的应用比较. 中国现代普通外科进展, 2018, 21(1): 28-30.
38.	章建全, 盛建国, 刁宗平, 等. 液体隔离法在颈部结节性病变经皮热消融治疗中的应用. 第二军医大学学报, 2014, 35(10): 1045-1052.
39.	孔月, 程志刚, 韩治宇, 等. 移动消融技术在微波消融治疗甲状腺良性结节中的应用价值. 解放军医学院学报, 2014, 35(7): 660-662, 691.
40.	Ahn HS, Kim SJ, Park SH, et al. Radiofrequency ablation of benign thyroid nodules: evaluation of the treatment efficacy using ultrasonography. Ultrasonography, 2016, 35(3): 244-252.
41.	单海琳, 邹大中, 邵清. 超声造影评价甲状腺结节激光消融疗效的应用. 东南大学学报: 医学版, 2016, 35(1): 36-40.
42.	Yue W, Wang S, Wang B, et al. Ultrasound guided percutaneous microwave ablation of benign thyroid nodules: safety and imaging follow-up in 222 patients. Eur J Radiol, 2013, 82(1): e11-e16.
43.	曲明, 杨强, 尹惠生, 等. 超声引导下甲状腺结节微波消融术围手术期处理. 实用医药杂志, 2016, 33(7): 599-602.

1. 金鑫荔, 卢伟. 甲状腺结节射频及微波消融治疗—现状及存在问题. 临床放射学杂志, 2017, 36(2): 295-297.
2. 吴震中, 章建全. 甲状腺结节微波热消融治疗的临床进展. 中国介入影像与治疗学, 2016, 13(12): 772-774.
3. 中华医学会内分泌学分会, 中华医学会外科学分会, 中国抗癌协会头颈肿瘤专业委员会, 等. 甲状腺结节和分化型甲状腺癌诊治指南. 中国肿瘤临床, 2012, 39(17): 1249-1272.
4. Haugen BR, Alexander EK, Bible KC, et al. 2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer. Thyroid, 2016, 26(1): 1-133.
5. 方建强, 赵维安, 李庆. 超声引导微波消融术治疗甲状腺良性结节的疗效与安全性分析. 中国临床医学影像杂志, 2019, 30(4): 250-252, 266.
6. 胡云飞, 蔡雨, 赵胜. 超声介导微波消融术与传统开放手术比较治疗甲状腺良性结节疗效的系统评价. 中国循证医学杂志, 2019, 19(3): 338-347.
7. Baek JH, Na DG, Lee JH, et al. Korean society of thyroid radiology recommendations for radiofrequency ablation of thyroid nodules. Korean Society of Thyroid Radiology, 2009. [2016-06-01]. http://thyroidimaging.kr/.
8. Na DG, Lee JH, Jung SL, et al. Radiofrequency ablation of benign thyroid nodules and recurrent thyroid cancers: consensus statement and recommendations. Korean J Radiol, 2012, 13(2): 117-125.
9. Kim JH, Baek JH, Lim HK, et al. 2017 Thyroid Radiofrequency Ablation Guideline: Korean Society of Thyroid Radiology. Korean J Radiol, 2018, 19(4): 632-655.
10. Garberoglio R, Aliberti C, Appetecchia M, et al. Radiofrequency ablation for thyroid nodules: which indications? The first Italian opinion statement. J Ultrasound, 2015, 18(4): 423-430.
11. 刁畅, 程若川. 消融治疗在甲状腺结节治疗中的误区与思考. 医学与哲学, 2015, 36(20): 16-21.
12. 浙江省抗癌协会甲状腺肿瘤专业委员会. 甲状腺良性结节、微小癌及颈部转移性淋巴结热消融治疗浙江省专家共识 (2015版). 中国普通外科杂志, 2016, 25(7): 944-946.
13. 中国医师协会甲状腺肿瘤消融治疗技术专家组, 中国抗癌协会甲状腺癌专业委员会, 中国医师协会介入医师分会超声介入专业委员会, 等. 甲状腺良性结节、微小癌及颈部转移性淋巴结热消融治疗专家共识 (2018版). 中国肿瘤, 2018, 27(10): 768-773.
14. 王宇思. 超声引导下经皮微波消融术在甲状腺良性结节治疗中的应用效果观察. 中国疗养医学, 2018, 27(6): 611-612.
15. 苏鸿辉, 吴玉帆, 陈耿臻. 超声引导下经皮微波消融治疗甲状腺良性结节的并发症. 现代医院, 2017, 17(1): 95-98.
16. 张波, 高琼, 李小毅, 等. 甲状腺结节射频消融的历史、现状及展望. 重庆医科大学学报, 2018, 43(12): 1537-1541.
17. Jung SL, Baek JH, Lee JH, et al. Efficacy and safety of radiofrequency ablation for benign thyroid nodules: a prospective multicenter study. Korean J Radiol, 2018, 19(1): 167-174.
18. Liu YJ, Qian LX, Liu D, et al. Ultrasound-guided microwave ablation in the treatment of benign thyroid nodules in 435 patients. Exp Biol Med (Maywood), 2017, 242(15): 1515-1523.
19. Sartori S, Mauri G, Tombesi P, et al. Ultrasound-guided percutaneous laser ablation is safe and effective in the treatment of small renal tumors in patients at increased bleeding risk. Int J Hyperthermia, 2018, 35(1): 19-25.
20. Mauri G, Nicosia L, Della Vigna P, et al. Percutaneous laser ablation for benign and malignant thyroid diseases. Ultrasonography, 2019, 38(1): 25-36.
21. Lim HK, Lee JH, Ha EJ, et al. Radiofrequency ablation of benign non-functioning thyroid nodules: 4-year follow-up results for 111 patients. Eur Radiol, 2013, 23(4): 1044-1049.
22. Valcavi R, Riganti F, Bertani A, et al. Percutaneous laser ablation of cold benign thyroid nodules: a 3-year follow-up study in 122 patients. Thyroid, 2010, 20(11): 1253-1261.
23. 刘玉辉, 王文玲, 王毅, 等. 超声引导下经皮微波消融甲状腺术后复发结节的临床研究. 临床耳鼻咽喉头颈外科杂志, 2015, 29(7): 622-624.
24. 闫磊, 章建全, 陈红琼, 等. 甲状腺结节微波消融治疗后6个月消融区细胞活性的酶组织化学检测. 第二军医大学学报, 2019, 40(1): 20-24.
25. Rahal Junior A, Falsarella PM, Mendes GF, et al. Percutaneous laser ablation of benign thyroid nodules: a one year follow-up study. Einstein (Sao Paulo), 2018, 16(4): eAO4279.
26. 马树花, 周平. 超声引导下热消融治疗甲状腺结节的应用. 中外医学研究, 2014, 12(13): 146-147, 148.
27. 郝少龙, 马纪红, 姜立新, 等. 热消融术在甲状腺结节微创治疗中的应用进展. 中华普通外科学文献: 电子版, 2016, 10(1): 77-80.
28. 章建全. 甲状腺结节经皮射频、微波消融治疗指南. 中国医刊, 2014, 49: 90-96.
29. Lee CU, Kim SJ, Sung JY, et al. Needle track tumor seeding after radiofrequency ablation of a thyroid tumor. Jpn J Radiol, 2014, 32(11): 661-663.
30. 张恒. 甲状腺结节射频消融治疗的效果探析. 中国医药指南, 2015, 13(17): 279-280.
31. 李建如, 罗渝昆. 射频消融技术在甲状腺结节治疗中的应用. 解放军医学院学报, 2016, 37(7): 807-809.
32. 纪莉, 吴凤林, 娄雪峰, 等. 超声弹性成像评估甲状腺良性结节射频消融效果的价值探讨. 中国超声医学杂志, 2014, 30(12): 1071-1073.
33. 刁宗平, 章建全, 盛建国, 等. 超声弹性成像在甲状腺良性结节射频消融中的应用价值及相关动态分析. 第二军医大学学报, 2017, 38(7): 947-950.
34. 孔月, 程志刚, 韩治宇, 等. 组织弹性定量分析在甲状腺良性病灶微波消融治疗中的应用价值. 中国超声医学杂志, 2014, 30(6): 489-492.
35. Huh JY, Baek JH, Choi H, et al. Symptomatic benign thyroid nodules: efficacy of additional radiofrequency ablation treatment session—prospective randomized study. Radiology, 2012, 263(3): 909-916.
36. 董文武, 张浩, 张平, 等. 甲状腺乳头状癌射频消融治疗后再手术5例临床分析. 中国实用外科杂志, 2015, 35(6): 653-655.
37. 杨映弘, 颜璟, 吴艳军, 等. 液体隔离带法与杠杆撬离法在超声引导下甲状腺微波消融术中的应用比较. 中国现代普通外科进展, 2018, 21(1): 28-30.
38. 章建全, 盛建国, 刁宗平, 等. 液体隔离法在颈部结节性病变经皮热消融治疗中的应用. 第二军医大学学报, 2014, 35(10): 1045-1052.
39. 孔月, 程志刚, 韩治宇, 等. 移动消融技术在微波消融治疗甲状腺良性结节中的应用价值. 解放军医学院学报, 2014, 35(7): 660-662, 691.
40. Ahn HS, Kim SJ, Park SH, et al. Radiofrequency ablation of benign thyroid nodules: evaluation of the treatment efficacy using ultrasonography. Ultrasonography, 2016, 35(3): 244-252.
41. 单海琳, 邹大中, 邵清. 超声造影评价甲状腺结节激光消融疗效的应用. 东南大学学报: 医学版, 2016, 35(1): 36-40.
42. Yue W, Wang S, Wang B, et al. Ultrasound guided percutaneous microwave ablation of benign thyroid nodules: safety and imaging follow-up in 222 patients. Eur J Radiol, 2013, 82(1): e11-e16.
43. 曲明, 杨强, 尹惠生, 等. 超声引导下甲状腺结节微波消融术围手术期处理. 实用医药杂志, 2016, 33(7): 599-602.

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Research progress of residual nodules after thermal ablation for benign thyroid nodules

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Next Article

Format

Content