WANG Fanghong 1 , ZHANG Hui 1 , CHU Huaizhu 2 , ZHU Kexiang 1 , ZHANG Lei 3 , MENG Wenbo 4 , ZHAO Sihua 5 , ZHOU Wence 1 , LI Xun 3
  • 1. The Second Department of General Surgery, The First Hospital of Lanzhou University, Lanzhou 730000, P. R. China;
  • 2. Department of Surgical Oncology, Qinghai Provincial People’s Hospital, Xining, 810000, P. R. China;
  • 3. The Fifth Department of General Surgery, The First Hospital of Lanzhou University, Lanzhou 730000, P. R. China;
  • 4. Department of VIP Surgery, The First Hospital of Lanzhou University, Lanzhou 730000, P. R. China;
  • 5. Cancer Center, The Second Hospital of Lanzhou University, Lanzhou 730000, P. R. China;
LI Xun, Email: lxdr21@126.com
elderly patients; Stage Ⅲ right colon cancer; complete mesocolic resection; clinical effect
10.7507/1007-9424.201907020
Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables References Cited by

Objective To investigate the clinical effect and prognosis of laparoscopic complete mesocolic resection (CME) in the treatment of elderly patients with stage Ⅲ right colon cancer.Methods Clinical data of 280 elderly patients (aged 60 years or older) who underwent stage Ⅲ right hemicolectomy in the First Hospital of Lanzhou University from 2010 to 2015 were collected. Among them, 160 patients underwent laparoscopic CME treatment were set as the observation group, and 120 patients underwent conventional laparotomy were set as the control group. The mean operative time, intraoperative blood loss, postoperative first anal exhaust time, number of lymph nodes dissection, number of positive lymph nodes, length of hospital stay and postoperative complications were compared between the two groups. The postoperative local recurrence rate, distant metastasis rate, 3-year cumulative survival rate and postoperative recurrence risk factors were analyzed.Results There were no statistically significant differences between the observation group and the control group in operative time, number of lymph node dissection, number of positive lymph nodes and postoperative distant metastasis rate (P>0.05). The amount of intraoperative blood loss, postoperative anal first exhaust time, days of hospitalization, and postoperative recurrence rate in the observation group were less or shorter or lower than those in the control group, with statistically significant differences (P<0.05). The 3-year survival rate in the observation group was higher than that in the control group (log-rank χ2 =11.865, P=0.001), and the disease free survival in the observation group was also higher than that in the control group (log-rank χ2=7.567, P=0.006). Logistic regression was used to analyze the cases of postoperative recurrence in the two groups, and it was found that the degree of tumor differentiation, vascular invasion and lymph node metastasis were independent risk factors for postoperative tumor recurrence.Conclusion Laparoscopic CME in the treatment of elderly patients with stage Ⅲ right colon cancer is effective, it is safe and feasible, which can effectively prolong the survival time of patients.

Citation： WANG Fanghong, ZHANG Hui, CHU Huaizhu, ZHU Kexiang, ZHANG Lei, MENG Wenbo, ZHAO Sihua, ZHOU Wence, LI Xun. The clinical outcomes and prognostic analysis of elderly patients with stage Ⅲ right colon cancer undergo laparoscopic complete mesocolon. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2020, 27(1): 69-74. doi: 10.7507/1007-9424.201907020 Copy

  • Previous Article

    Clinical results of Mini Maze procedure in atrial fibrillation patients with impaired left ventricular systolic function

  • Next Article

    加速康复外科的规范与安全