• Department of Thyroid and Parathyroid Surgery Center, West China Hospital, Sichuan University, Chengdu 610041, P. R. China;
WEI Tao, Email: weitaohxsurgeon@163.com
Export PDF Favorites Scan Get Citation

Objective To evaluate the safty of recurrent laryngeal nerve (RLN) and parathyroid if Pseudomonas aeruginosa injection (PAI) is used after total thyroidectomy and central neck dissection (CND).Methods From Mar. 2016 to Oct. 2017, we recruited 113 patients with papillary thyroid cancer (PTC) who accepted total thyroidectomy and CND. During operation, 1 mL of PAI was applied in 58 patients (local spray group) and 55 not (control group). The hoarseness, hypoparathyroidism, chylous fistula, drainage volume, hospital stay, and incidence of complications were compared between the two groups.Results The two groups embraced few difference in age, gender, BMI, tumor site, the diameter of tumor and the number of metastatic and the harvested lymph nodes (P>0.05). There were nobody who has suffered in hoarseness and permanent hypoparathyroidism in both groups at any time after operation. There was no significant differences of complication between the two groups. The drainage volume at 24 h after operation in the local spraying group was more than that in the control group, and the difference was statistically significant (P=0.023). There were 2 patients had chylous fistula after surgery in the control group but none in the local spray group. The total volumes of drainage, incidence of fever and incision infection, the mean stay in the hospital, and the postoperative pain score had no statistic significance in the both groups.Conclusion After total thyroidectomy and CND, local spraying of PAI in the wound cavity is safe and will not damage the recurrent laryngeal nerve.

Citation: MA Yu, ZENG Cuifang, ZOU Xiuhe, LEI Jianyong, ZHENG Xun, LI Zhihui, GONG Rixiang, ZHU Jingqiang, WEI Tao. Effect of local spraying of Pseudomonas aeruginosa injection on recurrent laryngeal nerve after total thyroidectomy and bilateral central lymph node dissection. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2020, 27(12): 1496-1500. doi: 10.7507/1007-9424.202004004 Copy

  • Previous Article

    主动脉瓣下隔膜的漏诊分析
  • Next Article

    先天性冠状动脉瘘外科治疗