Application of <i>ex vivo</i> liver resection and autotransplantation in hepatobiliary diseases_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Authors：

DONG Xiaoge ¹ , WANG Zhan ² , YUAN Jiaqi ² , LIU Haigang ¹ , DU Kaihao ¹ , ZHANG Shuai ¹ ,  HOU Lizhao ²

1. Qinghai University Clinical Medical College, Xining 810001, P. R. China;
2. Department of General Surgery, Affiliated Hospital of Qinghai University, Xining 810001, P. R. China;

Corresponding author：

HOU Lizhao, Email: zhuoyue_1973@163.com

Keywords：

ex vivo liver resection; autotransplantation; hepatic alveolar echinococcosis; liver cancer; cholangiocarcinoma

DOI：

10.7507/1007-9424.202405064

Video：

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Objective To summarize and analyze the application of ex vivo liver resection and autotransplantation (ELRA) in the treatment of hepatobiliary diseases. Method The related literature about ELRA used to treat various hepatobiliary space-occupyingdiseases at home and abroad in recent years was comprehensively searched and summarized. Results ELRA had overcome the limitations of limited operational space in traditional surgery for the treatment of hepatobiliary space-occupying diseases reduced dependence on donor livers, and avoided post-transplant rejection. It had been applied in the treatment of hepatic alveolar echinococcosis, liver cancer, cholangiocarcinoma, and rare liver space-occupying diseases. Conclusions With the maturation of ELRA techniques and the continuous improvement of ex vivo liver perfusion technology, along with rigorous preoperative evaluation and meticulous postoperative management, postoperative complications of ELRA have significantly decreased compared to the initial stages of its application. By strictly adhering to surgical indications, this procedure is expected to be used treatment in an increasing number of hepatobiliary space-occupying diseases.

Citation： DONG Xiaoge, WANG Zhan, YUAN Jiaqi, LIU Haigang, DU Kaihao, ZHANG Shuai, HOU Lizhao. Application of ex vivo liver resection and autotransplantation in hepatobiliary diseases. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2024, 31(10): 1265-1271. doi: 10.7507/1007-9424.202405064 Copy

1.	Shayan H. Organ transplantation: from myth to reality. J Invest Surg, 2001, 14(3): 135-138.
2.	Bergan A. Ancient myth, modern reality: a brief history of transplantation. J Biocommun, 1997, 24(4): 2-9.
3.	Bezinover D, Saner F. Organ transplantation in the modern era. BMC Anesthesiol, 2019, 19(1): 32. doi: 10.1186/s12871-019-0704-z.
4.	Pichlmayr R, Bretschneider HJ, Kirchner E, et al. Ex situ operation of the liver. A new possibility in liver surgery. Langenbecks Archiv Chir 1988, 373(2): 122-126.
5.	杨广顺, 吴孟超. 肝癌手术新方法半离体无血肝切除实验研究. 第一届全国肝癌学术会议论文集, 1988, J8: 120.
6.	Mantion GA, Vuitton DA. Auto- versus allo-transplantation of the liver for end-stage alveolar echinococcosis? Chin Med J (Engl), 2011, 124(18): 2803-2805.
7.	温浩, 董家鸿, 张金辉, 等. 体外肝切除联合自体肝移植治疗肝泡型包虫病. 中华消化外科杂志, 2011, 10(2): 148-149.
8.	庞北川, 张娜, 左邦佑, 等. 终末期肝泡型包虫病的肝移植治疗. 器官移植, 2024, 15(2): 163-170.
9.	卡地尔丁•艾海提, 叶建荣, 吐尔干艾力•阿吉. 离体肝脏冷缺血时间对自体肝移植术后早期肝脏功能及并发症影响研究. 中国实用外科杂志, 2023, 43(3): 315-318.
10.	田青山, 冯少培, 郭亚民, 等. 高原地区体外肝切除联合自体肝移植术治疗晚期肝泡型包虫病的术后并发症及其防治策略. 临床肝胆病杂志, 2021, 37(9): 2153-2160.
11.	Baimas-George M, Thompson KJ, Watson MD, et al. The technical aspects of ex vivo hepatectomy with autotransplantation: a systematic review and meta-analysis. Langenbecks Arch Surg, 2021, 406(7): 2177-2200.
12.	Wen H, Vuitton L, Tuxun T, et al. Echinococcosis: advances in the 21st century. Clin Microbiol Rev, 2019, 32(2): e00075-18. doi: 10.1128/CMR.00075-18.
13.	邓旭, 阳丹才让, 张灵强, 等. 泡型肝包虫病的外科治疗现状. 临床肝胆病杂志, 2021, 37(8): 1963-1965.
14.	王燚, 张宇, 邓绍平, 等. 自体肝移植技术治疗晚期肝泡型包虫病16例临床疗效分析. 实用医院临床杂志, 2019, 16(3): 59-63.
15.	四川省包虫病临床医学研究中心, 四川省医师协会包虫病专业委员会. 复杂肝泡型包虫病诊疗专家共识(2020版). 中国普外基础与临床杂志, 2020, 27(1): 18-23.
16.	Yang X, Qiu Y, Huang B, et al. Novel techniques and preliminary results of ex vivo liver resection and autotransplantation for end-stage hepatic alveolar echinococcosis: A study of 31 cases. Am J Transplant, 2018, 18(7): 1668-1679.
17.	Qiu Y, Yang X, Shen S, et al. Vascular infiltration-based surgical planning in treating end-stage hepatic alveolar echinococcosis with ex vivo liver resection and autotransplantation. Surgery, 2019, 165(5): 889-896.
18.	Jianyong L, Jingcheng H, Wentao W, et al. Ex vivo liver resection followed by autotransplantation to a patient with advanced alveolar echinococcosis with a replacement of the retrohepatic inferior vena cava using autogenous vein grafting: a case report and literature review. Medicine (Baltimore), 2015, 94(7): e514. doi: 10.1097/MD.0000000000000514.
19.	Shen S, Qiu Y, Yang X, et al. Remnant liver-to-standard liver volume ratio below 40% is safe in ex vivo liver resection and autotransplantation. J Gastrointest Surg, 2019, 23(10): 1964-1972.
20.	张宇, 杨冲, 王燚, 等. 离体肝切除和自体肝移植联合复杂肝静脉重建治疗终末期肝泡型包虫病. 中国普外基础与临床杂志, 2018, 25(10): 1236-1241.
21.	王文涛, 杨先伟, 严律南. 离体肝切除联合自体肝移植治疗晚期肝泡型包虫病. 中国普外基础与临床杂志, 2017, 24(7): 792-794.
22.	Shen S, Kong J, Qiu Y, et al. Ex vivo liver resection and autotransplantation versus allotransplantation for end-stage hepatic alveolar echinococcosis. Int J Infect Dis, 2019, 79: 87-93.
23.	邰沁文. 自体肝移植的临床和相关实验研究. 乌鲁木齐: 新疆医科大学, 2013.
24.	Yang C, Yang HJ, Deng SP, et al. Current status of ex-vivo liver resection and autologous liver transplantation for end-stage hepatic alveolar echinococcosis. Ann Palliat Med, 2020, 9(4): 2271-2278.
25.	Qiu Y, Huang B, Yang X, et al. Evaluating the benefits and risks of ex vivo liver resection and autotransplantation in treating hepatic end-stage alveolar echinococcosis. Clin Infect Dis, 2022, 75(8): 1289-1296.
26.	Wen H, Dong JH, Zhang JH, et al. Ex vivo liver resection and autotransplantation for end-stage alveolar echinococcosis: A case series. Am J Transplant, 2016, 16(2): 615-624.
27.	Yuan J, Chen X, Hou L, et al. Single-center experience of ex vivo liver resection and autotransplantation for complex hepatic alveolar echinoccosis. Front Surg, 2023, 10: 1089788. doi: 10.3389/fsurg.2023.1089788.
28.	唐几超. 根治性肝切除术与离体肝切除和自体肝移植术在晚期肝泡型包虫病患者中的应用比较. 泸州: 西南医科大学, 2021.
29.	杨文昊, 廖玉波, 黄良, 等. “在体优先”的离体肝切除联合自体肝移植术治疗晚期肝泡型包虫病的应用效果. 中国普外基础与临床杂志, 2022, 29(10): 1308-1312.
30.	Lv T, Xu G, Xu X, et al. A novel remnant liver-first strategy for liver autotransplantation in patients with end-stage hepatic alveolar echinococcosis: a retrospective case series. Int J Surg, 2023, 109(11): 3262-3272.
31.	Anwanwan D, Singh SK, Singh S, et al. Challenges in liver cancer and possible treatment approaches. Biochim Biophys Acta Rev Cancer, 2020, 1873(1): 188314. doi: 10.1016/j.bbcan.2019.188314.
32.	Liu M, Tseng TC, Jun DW, et al. Transition rates to cirrhosis and liver cancer by age, gender, disease and treatment status in Asian chronic hepatitis B patients. Hepatol Int, 2021, 15(1): 71-81.
33.	郝运, 李川, 文天夫, 等. 全球及中国的肝癌流行病学特征: 基于《2022全球癌症统计报告》解读. 中国普外基础与临床杂志, 2024, 31(7): 781-789.
34.	Omata M, Cheng AL, Kokudo N, et al. Asia-Pacific clinical practice guidelines on the management of hepatocellular carcinoma: a 2017 update. Hepatol Int, 2017, 11(4): 317-370.
35.	曾磊, 杨芦莎. 离体肝切除联合自体肝移植在特殊部位原发性肝癌根治术中的应用价值. 检验医学与临床, 2021, 18(21): 3175-3177.
36.	舒俊傑. 离体肝切除联合自体肝移植应用于肝脏复杂占位性病变的临床研究. 重庆: 中国人民解放军陆军军医大学, 2020.
37.	Lu Q, Aini A, Tang R, et al. From liver surgery to liver transplant surgery: new developments in autotransplantation. Curr Opin Organ Transplant, 2022, 27(4): 337-345.
38.	Zawistowski M, Nowaczyk J, Jakubczyk M, et al. Outcomes of ex vivo liver resection and autotransplantation: A systematic review and meta-analysis. Surgery, 2020, 168(4): 631-642.
39.	Weiner J, Hemming A, Levi D, et al. Ex vivo liver resection and autotransplantation: should it be used more frequently? Ann Surg, 2022, 276(5): 854-859.
40.	杨占宇, 卢倩. 体外肝切除自体肝移植治疗肝细胞癌. 中华普通外科学文献(电子版), 2022, 16(3): 182. doi: 10.3877/cma.j.issn.1674-0793-2022.03.018.
41.	Ilyas SI, Gores GJ. Pathogenesis, diagnosis, and management of cholangiocarcinoma. Gastroenterology, 2013, 145(6): 1215-1229.
42.	Brindley PJ, Bachini M, Ilyas SI, et al. Cholangiocarcinoma. Nat Rev Dis Primers, 2021, 7(1): 65. doi: 10.1038/s41572-021-00300-2.
43.	Tyson GL, El-Serag HB. Risk factors for cholangiocarcinoma. Hepatology, 2011, 54(1): 173-184.
44.	Chui AK, Island ER, Rao AR, et al. The longest survivor and first potential cure of an advanced cholangiocarcinoma by ex vivo resection and autotransplantation: a case report and review of the literature. Am Surg, 2003, 69(5): 441-444.
45.	Chen D, Zhang W, Wei L. Ex vivo resection, vessel reconstruction and liver autotransplantation for cholangiocarcinoma: A report of two cases. Asian J Surg, 2024, 47(6): 2625-2631.
46.	Ozsoy M, Ozsoy Z, Yilmaz S, et al. Ex situ liver resection and partial liver autotransplantation for advanced cholangiocarcinoma. Niger J Surg, 2019, 25(1): 97-100.
47.	Baker MA, Maley WR, Needleman L, et al. Ex vivo resection of hepatic neoplasia and autotransplantation: a case report and review of the literature. J Gastrointest Surg, 2015, 19(6): 1169-1176.
48.	Hu CL, Han X, Gao ZZ, et al. Systematic sequential therapy for ex vivo liver resection and autotransplantation: A case report and review of literature. World J Gastrointest Surg, 2023, 15(11): 2663-2673.
49.	徐珏华, 刘帅, 严盛, 等. 胆管癌患者行离体肝切除联合自体肝移植的围手术期护理. 中华急危重症护理杂志, 2023, 4(10): 926-929.
50.	Baimas-George M, Strand MS, Davis JM, et al. Future liver remnant augmentation preceding ex vivo hepatectomy with IVC replacement: a strategy to achieve R0 margins. Langenbecks Arch Surg, 2023, 408(1): 156. doi: 10.1007/s00423-023-02902-8.
51.	Liu W, Li G, Jin Y, et al. Autologous liver transplantation for unresectable hepatobiliary malignancies in enhanced recovery after surgery model. Open Med (Wars), 2024, 19(1): 20240926. doi: 10.1515/med-2024-0926.
52.	Wang H, Zhang CC, Ou YJ, et al. Ex vivo liver resection followed by autotransplantation in radical resection of gastric cancer liver metastases: A case report. World J Clin Cases, 2021, 9(17): 4221-4229.
53.	Hager J, Sergi CM. Hepatoblastoma//Sergi CM. Liver Cancer [Internet]. Brisbane (AU) : Exon Publications; 2021 Apr 6. Chapter 8.
54.	Murawski M, Weeda VB, Czauderna P. Surgical management in hepatoblastoma: points to take. Pediatr Surg Int, 2023, 39(1): 81. doi: 10.1007/s00383-022-05356-z.
55.	Shi SJ, Wang DL, Hu W, et al. Ex vivo liver resection and autotransplantation with cardiopulmonary bypass for hepatoblastoma in children: A case report. Pediatr Transplant, 2018, 22(7): e13268. doi: 10.1111/petr.13268.
56.	董安华, 孙延东, 王峰, 等. 改良自体肝移植治疗儿童肝母细胞瘤1例并文献复习. 实用器官移植电子杂志, 2023, 11(4): 350-352.
57.	Garcia-Pagán JC, Valla DC. Primary Budd-Chiari syndrome. N Engl J Med, 2023, 388(14): 1307-1316.
58.	Wang C, Qiu Y, Wang W. Application of ex vivo liver resection and autotransplantation in treating Budd-Chiari syndrome secondary to end-stage hepatic alveolar echinococcosis: A case series. Medicine (Baltimore), 2021, 100(34): e27075. doi: 10.1097/MD.0000000000027075.
59.	Salas S, Resseguier N, Blay JY, et al. Prediction of local and metastatic recurrence in solitary fibrous tumor: construction of a risk calculator in a multicenter cohort from the French Sarcoma Group (FSG) database. Ann Oncol, 2017, 28(8): 1979-1987.
60.	Sun Z, Ding Y, Jiang Y, et al. Ex situ hepatectomy and liver autotransplantation for a treating giant solitary fibrous tumor: A case report. Oncol Lett, 2019, 17(1): 1042-1052.
61.	Li M, Mei YX, Wen JH, et al. Hepatoid adenocarcinoma-clinicopathological features and molecular characteristics. Cancer Lett, 2023, 59: 216104. doi: 10.1016/j.canlet.2023.216104.
62.	Wang FQ, Lu Q, Yan J, et al. Ex vivo hepatectomy and partial liver autotransplantation for hepatoid adenocarcinoma: A case report. Oncol Lett, 2015, 9(5): 2199-2204.
63.	Matsuoka N, Weiner JI, Griesemer AD, et al. Ex vivo pancreaticoduodenectomy and liver autotransplantation for pancreatic head tumor with extensive involvement of the hepatoduodenal ligament. Liver Transpl, 2015, 21(12): 1553-1556.
64.	Tuxun T, Li T, Apaer S, et al. Ex vivo liver resection and autotransplantation as surgical option for zoneⅡ-Ⅲ leiomyosarcoma of IVC: A case report and literature review. Front Oncol, 2021, 11: 690617. doi: 10.3389/fonc.2021.690617.
65.	张国锋, 丁一, 杨合英, 等. 离体肝切除治疗儿童炎性肌纤维母细胞瘤1例报告. 中国实用外科杂志, 2022, 42(4): 477-478, 480.
66.	Buchholz BM, Pinter Carvalheiro da Silva Boteon A, Taniere P, et al. Autotransplantation of the liver for ex vivo resection of intrahepatic caval leiomyosarcoma: A case report. Exp Clin Transplant, 2020, 18(3): 396-401.
67.	Obana A, Sato Y. Autologous partial liver transplantation for a symptomatic giant hepatic hemangioma. A case report. Transplant Proc, 2022, 54(10): 2787-2790.
68.	罗晓艳, 巫焕珍, 刘毅, 等. 粤北地区医学生器官捐赠知识、态度和意愿调查. 现代预防医学, 2016, 43(17): 3164-3168.

1. Shayan H. Organ transplantation: from myth to reality. J Invest Surg, 2001, 14(3): 135-138.
2. Bergan A. Ancient myth, modern reality: a brief history of transplantation. J Biocommun, 1997, 24(4): 2-9.
3. Bezinover D, Saner F. Organ transplantation in the modern era. BMC Anesthesiol, 2019, 19(1): 32. doi: 10.1186/s12871-019-0704-z.
4. Pichlmayr R, Bretschneider HJ, Kirchner E, et al. Ex situ operation of the liver. A new possibility in liver surgery. Langenbecks Archiv Chir 1988, 373(2): 122-126.
5. 杨广顺, 吴孟超. 肝癌手术新方法半离体无血肝切除实验研究. 第一届全国肝癌学术会议论文集, 1988, J8: 120.
6. Mantion GA, Vuitton DA. Auto- versus allo-transplantation of the liver for end-stage alveolar echinococcosis? Chin Med J (Engl), 2011, 124(18): 2803-2805.
7. 温浩, 董家鸿, 张金辉, 等. 体外肝切除联合自体肝移植治疗肝泡型包虫病. 中华消化外科杂志, 2011, 10(2): 148-149.
8. 庞北川, 张娜, 左邦佑, 等. 终末期肝泡型包虫病的肝移植治疗. 器官移植, 2024, 15(2): 163-170.
9. 卡地尔丁•艾海提, 叶建荣, 吐尔干艾力•阿吉. 离体肝脏冷缺血时间对自体肝移植术后早期肝脏功能及并发症影响研究. 中国实用外科杂志, 2023, 43(3): 315-318.
10. 田青山, 冯少培, 郭亚民, 等. 高原地区体外肝切除联合自体肝移植术治疗晚期肝泡型包虫病的术后并发症及其防治策略. 临床肝胆病杂志, 2021, 37(9): 2153-2160.
11. Baimas-George M, Thompson KJ, Watson MD, et al. The technical aspects of ex vivo hepatectomy with autotransplantation: a systematic review and meta-analysis. Langenbecks Arch Surg, 2021, 406(7): 2177-2200.
12. Wen H, Vuitton L, Tuxun T, et al. Echinococcosis: advances in the 21st century. Clin Microbiol Rev, 2019, 32(2): e00075-18. doi: 10.1128/CMR.00075-18.
13. 邓旭, 阳丹才让, 张灵强, 等. 泡型肝包虫病的外科治疗现状. 临床肝胆病杂志, 2021, 37(8): 1963-1965.
14. 王燚, 张宇, 邓绍平, 等. 自体肝移植技术治疗晚期肝泡型包虫病16例临床疗效分析. 实用医院临床杂志, 2019, 16(3): 59-63.
15. 四川省包虫病临床医学研究中心, 四川省医师协会包虫病专业委员会. 复杂肝泡型包虫病诊疗专家共识(2020版). 中国普外基础与临床杂志, 2020, 27(1): 18-23.
16. Yang X, Qiu Y, Huang B, et al. Novel techniques and preliminary results of ex vivo liver resection and autotransplantation for end-stage hepatic alveolar echinococcosis: A study of 31 cases. Am J Transplant, 2018, 18(7): 1668-1679.
17. Qiu Y, Yang X, Shen S, et al. Vascular infiltration-based surgical planning in treating end-stage hepatic alveolar echinococcosis with ex vivo liver resection and autotransplantation. Surgery, 2019, 165(5): 889-896.
18. Jianyong L, Jingcheng H, Wentao W, et al. Ex vivo liver resection followed by autotransplantation to a patient with advanced alveolar echinococcosis with a replacement of the retrohepatic inferior vena cava using autogenous vein grafting: a case report and literature review. Medicine (Baltimore), 2015, 94(7): e514. doi: 10.1097/MD.0000000000000514.
19. Shen S, Qiu Y, Yang X, et al. Remnant liver-to-standard liver volume ratio below 40% is safe in ex vivo liver resection and autotransplantation. J Gastrointest Surg, 2019, 23(10): 1964-1972.
20. 张宇, 杨冲, 王燚, 等. 离体肝切除和自体肝移植联合复杂肝静脉重建治疗终末期肝泡型包虫病. 中国普外基础与临床杂志, 2018, 25(10): 1236-1241.
21. 王文涛, 杨先伟, 严律南. 离体肝切除联合自体肝移植治疗晚期肝泡型包虫病. 中国普外基础与临床杂志, 2017, 24(7): 792-794.
22. Shen S, Kong J, Qiu Y, et al. Ex vivo liver resection and autotransplantation versus allotransplantation for end-stage hepatic alveolar echinococcosis. Int J Infect Dis, 2019, 79: 87-93.
23. 邰沁文. 自体肝移植的临床和相关实验研究. 乌鲁木齐: 新疆医科大学, 2013.
24. Yang C, Yang HJ, Deng SP, et al. Current status of ex-vivo liver resection and autologous liver transplantation for end-stage hepatic alveolar echinococcosis. Ann Palliat Med, 2020, 9(4): 2271-2278.
25. Qiu Y, Huang B, Yang X, et al. Evaluating the benefits and risks of ex vivo liver resection and autotransplantation in treating hepatic end-stage alveolar echinococcosis. Clin Infect Dis, 2022, 75(8): 1289-1296.
26. Wen H, Dong JH, Zhang JH, et al. Ex vivo liver resection and autotransplantation for end-stage alveolar echinococcosis: A case series. Am J Transplant, 2016, 16(2): 615-624.
27. Yuan J, Chen X, Hou L, et al. Single-center experience of ex vivo liver resection and autotransplantation for complex hepatic alveolar echinoccosis. Front Surg, 2023, 10: 1089788. doi: 10.3389/fsurg.2023.1089788.
28. 唐几超. 根治性肝切除术与离体肝切除和自体肝移植术在晚期肝泡型包虫病患者中的应用比较. 泸州: 西南医科大学, 2021.
29. 杨文昊, 廖玉波, 黄良, 等. “在体优先”的离体肝切除联合自体肝移植术治疗晚期肝泡型包虫病的应用效果. 中国普外基础与临床杂志, 2022, 29(10): 1308-1312.
30. Lv T, Xu G, Xu X, et al. A novel remnant liver-first strategy for liver autotransplantation in patients with end-stage hepatic alveolar echinococcosis: a retrospective case series. Int J Surg, 2023, 109(11): 3262-3272.
31. Anwanwan D, Singh SK, Singh S, et al. Challenges in liver cancer and possible treatment approaches. Biochim Biophys Acta Rev Cancer, 2020, 1873(1): 188314. doi: 10.1016/j.bbcan.2019.188314.
32. Liu M, Tseng TC, Jun DW, et al. Transition rates to cirrhosis and liver cancer by age, gender, disease and treatment status in Asian chronic hepatitis B patients. Hepatol Int, 2021, 15(1): 71-81.
33. 郝运, 李川, 文天夫, 等. 全球及中国的肝癌流行病学特征: 基于《2022全球癌症统计报告》解读. 中国普外基础与临床杂志, 2024, 31(7): 781-789.
34. Omata M, Cheng AL, Kokudo N, et al. Asia-Pacific clinical practice guidelines on the management of hepatocellular carcinoma: a 2017 update. Hepatol Int, 2017, 11(4): 317-370.
35. 曾磊, 杨芦莎. 离体肝切除联合自体肝移植在特殊部位原发性肝癌根治术中的应用价值. 检验医学与临床, 2021, 18(21): 3175-3177.
36. 舒俊傑. 离体肝切除联合自体肝移植应用于肝脏复杂占位性病变的临床研究. 重庆: 中国人民解放军陆军军医大学, 2020.
37. Lu Q, Aini A, Tang R, et al. From liver surgery to liver transplant surgery: new developments in autotransplantation. Curr Opin Organ Transplant, 2022, 27(4): 337-345.
38. Zawistowski M, Nowaczyk J, Jakubczyk M, et al. Outcomes of ex vivo liver resection and autotransplantation: A systematic review and meta-analysis. Surgery, 2020, 168(4): 631-642.
39. Weiner J, Hemming A, Levi D, et al. Ex vivo liver resection and autotransplantation: should it be used more frequently? Ann Surg, 2022, 276(5): 854-859.
40. 杨占宇, 卢倩. 体外肝切除自体肝移植治疗肝细胞癌. 中华普通外科学文献(电子版), 2022, 16(3): 182. doi: 10.3877/cma.j.issn.1674-0793-2022.03.018.
41. Ilyas SI, Gores GJ. Pathogenesis, diagnosis, and management of cholangiocarcinoma. Gastroenterology, 2013, 145(6): 1215-1229.
42. Brindley PJ, Bachini M, Ilyas SI, et al. Cholangiocarcinoma. Nat Rev Dis Primers, 2021, 7(1): 65. doi: 10.1038/s41572-021-00300-2.
43. Tyson GL, El-Serag HB. Risk factors for cholangiocarcinoma. Hepatology, 2011, 54(1): 173-184.
44. Chui AK, Island ER, Rao AR, et al. The longest survivor and first potential cure of an advanced cholangiocarcinoma by ex vivo resection and autotransplantation: a case report and review of the literature. Am Surg, 2003, 69(5): 441-444.
45. Chen D, Zhang W, Wei L. Ex vivo resection, vessel reconstruction and liver autotransplantation for cholangiocarcinoma: A report of two cases. Asian J Surg, 2024, 47(6): 2625-2631.
46. Ozsoy M, Ozsoy Z, Yilmaz S, et al. Ex situ liver resection and partial liver autotransplantation for advanced cholangiocarcinoma. Niger J Surg, 2019, 25(1): 97-100.
47. Baker MA, Maley WR, Needleman L, et al. Ex vivo resection of hepatic neoplasia and autotransplantation: a case report and review of the literature. J Gastrointest Surg, 2015, 19(6): 1169-1176.
48. Hu CL, Han X, Gao ZZ, et al. Systematic sequential therapy for ex vivo liver resection and autotransplantation: A case report and review of literature. World J Gastrointest Surg, 2023, 15(11): 2663-2673.
49. 徐珏华, 刘帅, 严盛, 等. 胆管癌患者行离体肝切除联合自体肝移植的围手术期护理. 中华急危重症护理杂志, 2023, 4(10): 926-929.
50. Baimas-George M, Strand MS, Davis JM, et al. Future liver remnant augmentation preceding ex vivo hepatectomy with IVC replacement: a strategy to achieve R0 margins. Langenbecks Arch Surg, 2023, 408(1): 156. doi: 10.1007/s00423-023-02902-8.
51. Liu W, Li G, Jin Y, et al. Autologous liver transplantation for unresectable hepatobiliary malignancies in enhanced recovery after surgery model. Open Med (Wars), 2024, 19(1): 20240926. doi: 10.1515/med-2024-0926.
52. Wang H, Zhang CC, Ou YJ, et al. Ex vivo liver resection followed by autotransplantation in radical resection of gastric cancer liver metastases: A case report. World J Clin Cases, 2021, 9(17): 4221-4229.
53. Hager J, Sergi CM. Hepatoblastoma//Sergi CM. Liver Cancer [Internet]. Brisbane (AU) : Exon Publications; 2021 Apr 6. Chapter 8.
54. Murawski M, Weeda VB, Czauderna P. Surgical management in hepatoblastoma: points to take. Pediatr Surg Int, 2023, 39(1): 81. doi: 10.1007/s00383-022-05356-z.
55. Shi SJ, Wang DL, Hu W, et al. Ex vivo liver resection and autotransplantation with cardiopulmonary bypass for hepatoblastoma in children: A case report. Pediatr Transplant, 2018, 22(7): e13268. doi: 10.1111/petr.13268.
56. 董安华, 孙延东, 王峰, 等. 改良自体肝移植治疗儿童肝母细胞瘤1例并文献复习. 实用器官移植电子杂志, 2023, 11(4): 350-352.
57. Garcia-Pagán JC, Valla DC. Primary Budd-Chiari syndrome. N Engl J Med, 2023, 388(14): 1307-1316.
58. Wang C, Qiu Y, Wang W. Application of ex vivo liver resection and autotransplantation in treating Budd-Chiari syndrome secondary to end-stage hepatic alveolar echinococcosis: A case series. Medicine (Baltimore), 2021, 100(34): e27075. doi: 10.1097/MD.0000000000027075.
59. Salas S, Resseguier N, Blay JY, et al. Prediction of local and metastatic recurrence in solitary fibrous tumor: construction of a risk calculator in a multicenter cohort from the French Sarcoma Group (FSG) database. Ann Oncol, 2017, 28(8): 1979-1987.
60. Sun Z, Ding Y, Jiang Y, et al. Ex situ hepatectomy and liver autotransplantation for a treating giant solitary fibrous tumor: A case report. Oncol Lett, 2019, 17(1): 1042-1052.
61. Li M, Mei YX, Wen JH, et al. Hepatoid adenocarcinoma-clinicopathological features and molecular characteristics. Cancer Lett, 2023, 59: 216104. doi: 10.1016/j.canlet.2023.216104.
62. Wang FQ, Lu Q, Yan J, et al. Ex vivo hepatectomy and partial liver autotransplantation for hepatoid adenocarcinoma: A case report. Oncol Lett, 2015, 9(5): 2199-2204.
63. Matsuoka N, Weiner JI, Griesemer AD, et al. Ex vivo pancreaticoduodenectomy and liver autotransplantation for pancreatic head tumor with extensive involvement of the hepatoduodenal ligament. Liver Transpl, 2015, 21(12): 1553-1556.
64. Tuxun T, Li T, Apaer S, et al. Ex vivo liver resection and autotransplantation as surgical option for zoneⅡ-Ⅲ leiomyosarcoma of IVC: A case report and literature review. Front Oncol, 2021, 11: 690617. doi: 10.3389/fonc.2021.690617.
65. 张国锋, 丁一, 杨合英, 等. 离体肝切除治疗儿童炎性肌纤维母细胞瘤1例报告. 中国实用外科杂志, 2022, 42(4): 477-478, 480.
66. Buchholz BM, Pinter Carvalheiro da Silva Boteon A, Taniere P, et al. Autotransplantation of the liver for ex vivo resection of intrahepatic caval leiomyosarcoma: A case report. Exp Clin Transplant, 2020, 18(3): 396-401.
67. Obana A, Sato Y. Autologous partial liver transplantation for a symptomatic giant hepatic hemangioma. A case report. Transplant Proc, 2022, 54(10): 2787-2790.
68. 罗晓艳, 巫焕珍, 刘毅, 等. 粤北地区医学生器官捐赠知识、态度和意愿调查. 现代预防医学, 2016, 43(17): 3164-3168.

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Application of ex vivo liver resection and autotransplantation in hepatobiliary diseases

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