The Influence of Community Respiratory Support Center on Stable Chronic Obstructive Pulmonary Disease_Chinese Journal of Respiratory and Critical Care Medicine

Authors：

LiFangfu ¹ , YanHuiyu ² ,  JiaWeiguo ¹

1. The Center of Gerontology and Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, China;
2. ;

Corresponding author：

JiaWeiguo, Email: jiawg@vip.163.com

Keywords：

Community respiratory support center; Oxygen therapy; Ambroxol for atomization; Budesonide and formoterol; Compliance; Chronic obstructive pulmonary disease

DOI：

10.7507/1671-6205.2014114

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Objective To explore the effect of respiratory support in Community Respiratory Support Center on patients with chronic obstructive pulmonary disease (COPD) in stable phase. Methods Sixty-four GOLD gradeⅢpatients with stable COPD over age of 55 years were randomly divided into two groups.A respiratory support group received respiratory support in Community Respiratory Support Center, including health education, long-term oxygen therapy (LTOT), long-term ambroxol for atomization, long-term budesonide and formoterol for inhalation.A control group were prescribed budesonide and formoterol for inhalation when recruited, informed LTOT and long-term ambroxol for atomization at home, and follow-up visits to clinic every month. Results After 24 months of treatment in the respiratory support group, SpO₂, PaO₂, FEV₁%pred, 6MWD, BMI, and ALB increased, mMRC, CAT, Hb, PaCO₂ decreased (P < 0.05).While in the control group, FEV₁%pred decreased, mMRC and CAT increased (P < 0.05), other indexes did not change significantly (P > 0.05).The times of acute exacerbation and hospitalization of the respiratory support group was less than that in the control group(P < 0.05). Conclusions Establishing Community Respiratory Support Center will benefit patients with stable COPD correct hypoxemia, slow the deterioration of lung function, improve the nutritional status of patients, and can also increase patients compliance to treatment.

Citation： LiFangfu, YanHuiyu, JiaWeiguo. The Influence of Community Respiratory Support Center on Stable Chronic Obstructive Pulmonary Disease. Chinese Journal of Respiratory and Critical Care Medicine, 2014, 13(5): 464-468. doi: 10.7507/1671-6205.2014114 Copy

1.	Zieliński J, Tobiasz M, Hawry kiewicz I, et al.Effects of long-term oxygen therapy on pulmonary hemodynamics in COPD patients:a 6-year prospective study.Chest, 1998, 113:65-70.
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1. Zieliński J, Tobiasz M, Hawry kiewicz I, et al.Effects of long-term oxygen therapy on pulmonary hemodynamics in COPD patients:a 6-year prospective study.Chest, 1998, 113:65-70.
2. Tashkin DP, Rennard SI, Martin P, et al.Efficacy and safety of budesonide and formoterol in one pressurized metered-dose inhaler in patients with moderate to very severe chronic obstructive pulmonary disease:results of a 6-month randomized clinical trial.Drugs, 2008, 68:1975-2000.
3. GOLD Executive Committee.Global strategy for the diagnosis, management, and prevention of COPD, 2011.www.goldcopd.org.
4. GOLD Executive Committee.Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease (update 2014).www.goldcopd.org.
5. Barnes PJ.Chronic obstructive pulmonary disease.N Engl J Med, 2000, 343:269-280.
6. Nomoyama ML, Brooks D, Guyatt GH, et al.Effect of oxygen on health quality of life in patients with chronic obstructive pulmonary disease with transient exertion hypoxemia.Am J Respir Crit Care Med, 2007, 176:343-349.
7. 余维巍, 夏秦.长期家庭氧疗对慢性阻塞性肺病的影响.中华康复, 2012, 27:280-281.
8. Vestbo J, Anderson JA, Calverley PM, et al.Adherence to inhaled therapy, mortality and hospital admission in COPD.Thorax, 2009, 64:939-943.
9. Wood-Baker R, Reid D, Robinson A, et al.Clinical trial of community nurse mentoring to improve self-management in patients with chronic obstructive pulmonary disease.Int J Chron Obstruct Pulmon Dis, 2012, 7:407-413.

Chinese Journal of Respiratory and Critical Care Medicine

The Influence of Community Respiratory Support Center on Stable Chronic Obstructive Pulmonary Disease

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