半胱氨酰白三烯与呼吸系统疾病的研究进展_Chinese Journal of Respiratory and Critical Care Medicine

Authors：

邓玉英 ¹ ,  唐华平 ² , 毛琦善 ¹ , 邹慎春 ¹

1. ;
2. ;

Corresponding author：

唐华平, Email: 15610039985@163.com

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DOI：

10.7507/1671-6205.201803033

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Citation： 邓玉英, 唐华平, 毛琦善, 邹慎春. 半胱氨酰白三烯与呼吸系统疾病的研究进展. Chinese Journal of Respiratory and Critical Care Medicine, 2020, 19(3): 291-298. doi: 10.7507/1671-6205.201803033 Copy

1.	Heidenreich KA, Corser-Jensen CE. 5-Lipoxygenase-activating protein inhibitors: promising drugs for treating acute and chronic neuroinflammation following brain injury[M]//New therapeutics for traumatic brain injury. 2017: 199-210.3444555.
2.	Kanaoka Y, Boyce JA. Cysteinyl leukotrienes and their receptors; emerging concepts. Allergy Asthma Immunol Res, 2014, 6(4): 288-295.
3.	Salimi M, Stöger L, Liu W, et al. Cysteinyl leukotriene E4 activates human group 2 innate lymphoid cells and enhances the effect of prostaglandin D2 and epithelial cytokines. J Allergy Clin Immunol, 2017, 140(4): 1090-1100.
4.	Peters-Golden M, Sampson AP. Cysteinyl leukotriene interactions with other mediators and with glucocorticosteroids during airway inflammation. J Allergy Clin Immunol, 2003, 111(1): S37-S48.
5.	Vannella KM, McMillan TR, Charbeneau RP, et al. Cysteinyl leukotrienes are autocrine and paracrine regulators of fibrocyte function. J Immunol, 2007, 179(11): 7883-7890.
6.	Lee E, Robertson T, Smith J, et al. Leukotriene receptor antagonists and synthesis inhibitors reverse survival in eosinophils of asthmatic individuals. Am J Respir Crit Care Med, 2000, 161(6): 1881-1886.
7.	Bandeira-Melo C, Woods LJ, Phoofolo M, et al. Intracrine cysteinyl leukotriene receptor–mediated signaling of eosinophil vesicular transport–mediated interleukin-4 secretion. J Exp Med, 2002, 196(6): 841-850.
8.	Lin DA, Boyce JA. IL-4 regulates MEK expression required for lysophosphatidic acid-mediated chemokine generation by human mast cells. J Immunol, 2005, 175(8): 5430-5438.
9.	Jiang Y, Kanaoka Y, Feng C, et al. Cutting edge: Interleukin 4-dependent mast cell proliferation requires autocrine/intracrine cysteinyl leukotriene-induced signaling. J Immunol, 2006, 177(5): 2755-2759.
10.	Doherty TA, Khorram N, Lund S, et al. Lung type 2 innate lymphoid cells express cysteinyl leukotriene receptor 1, which regulates TH2 cytokine production. J Allergy Clin Immunol, 2013, 132(1): 205-213.
11.	Singh RK, Gupta S, Dastidar S, et al. Cysteinyl leukotrienes and their receptors: molecular and functional characteristics. Pharmacology, 2010, 85(6): 336-349.
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13.	Espinosa K, Bossé Y, Stankova J, et al. CysLT1 receptor upregulation by TGF-β and IL-13 is associated with bronchial smooth muscle cell proliferation in response to LTD4. J Allergy Clin Immunol, 2003, 111(5): 1032-1040.
14.	Shirasaki H, Kanaizumi E, Himi T. Leukotriene D4 induces chemotaxis in human eosinophilc cell line, EoL-1 cells via CysLT1 receptor activation. Heliyon, 2017, 3(11): e00464.
15.	Lazarinis N, Bood J, Gomez C, et al. Leukotriene E4 induces airflow obstruction and mast cell activation via the CysLT1 receptor. J Allergy Clin Immunol, 2018, 2018: S0091-6749.
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1. Heidenreich KA, Corser-Jensen CE. 5-Lipoxygenase-activating protein inhibitors: promising drugs for treating acute and chronic neuroinflammation following brain injury[M]//New therapeutics for traumatic brain injury. 2017: 199-210.3444555.
2. Kanaoka Y, Boyce JA. Cysteinyl leukotrienes and their receptors; emerging concepts. Allergy Asthma Immunol Res, 2014, 6(4): 288-295.
3. Salimi M, Stöger L, Liu W, et al. Cysteinyl leukotriene E4 activates human group 2 innate lymphoid cells and enhances the effect of prostaglandin D2 and epithelial cytokines. J Allergy Clin Immunol, 2017, 140(4): 1090-1100.
4. Peters-Golden M, Sampson AP. Cysteinyl leukotriene interactions with other mediators and with glucocorticosteroids during airway inflammation. J Allergy Clin Immunol, 2003, 111(1): S37-S48.
5. Vannella KM, McMillan TR, Charbeneau RP, et al. Cysteinyl leukotrienes are autocrine and paracrine regulators of fibrocyte function. J Immunol, 2007, 179(11): 7883-7890.
6. Lee E, Robertson T, Smith J, et al. Leukotriene receptor antagonists and synthesis inhibitors reverse survival in eosinophils of asthmatic individuals. Am J Respir Crit Care Med, 2000, 161(6): 1881-1886.
7. Bandeira-Melo C, Woods LJ, Phoofolo M, et al. Intracrine cysteinyl leukotriene receptor–mediated signaling of eosinophil vesicular transport–mediated interleukin-4 secretion. J Exp Med, 2002, 196(6): 841-850.
8. Lin DA, Boyce JA. IL-4 regulates MEK expression required for lysophosphatidic acid-mediated chemokine generation by human mast cells. J Immunol, 2005, 175(8): 5430-5438.
9. Jiang Y, Kanaoka Y, Feng C, et al. Cutting edge: Interleukin 4-dependent mast cell proliferation requires autocrine/intracrine cysteinyl leukotriene-induced signaling. J Immunol, 2006, 177(5): 2755-2759.
10. Doherty TA, Khorram N, Lund S, et al. Lung type 2 innate lymphoid cells express cysteinyl leukotriene receptor 1, which regulates TH2 cytokine production. J Allergy Clin Immunol, 2013, 132(1): 205-213.
11. Singh RK, Gupta S, Dastidar S, et al. Cysteinyl leukotrienes and their receptors: molecular and functional characteristics. Pharmacology, 2010, 85(6): 336-349.
12. Liu M, Yokomizo T. The role of leukotrienes in allergic diseases. Allergol Int, 2015, 64(1): 17-26.
13. Espinosa K, Bossé Y, Stankova J, et al. CysLT1 receptor upregulation by TGF-β and IL-13 is associated with bronchial smooth muscle cell proliferation in response to LTD4. J Allergy Clin Immunol, 2003, 111(5): 1032-1040.
14. Shirasaki H, Kanaizumi E, Himi T. Leukotriene D4 induces chemotaxis in human eosinophilc cell line, EoL-1 cells via CysLT1 receptor activation. Heliyon, 2017, 3(11): e00464.
15. Lazarinis N, Bood J, Gomez C, et al. Leukotriene E4 induces airflow obstruction and mast cell activation via the CysLT1 receptor. J Allergy Clin Immunol, 2018, 2018: S0091-6749.
16. Lazarinis N, Bood J, Gomez C, et al. The CysLT 1 receptor antagonist montelukast inhibits mast cell activation induced by inhaled leukotriene E 4 in subjects with asthma. Eur Respir J, 2016, 48(60): OA1983.
17. Osman J, Savari S, Chandrashekar N K, et al. Cysteinyl leukotriene receptor 1 facilitates tumorigenesis in a mouse model of colitis-associated colon cancer. Oncotarget, 2017, 8(21): 34773.
18. Bellamkonda K, Chandrashekar NK, Osman J, et al. The eicosanoids leukotriene D 4 and prostaglandin E 2 promote the tumorigenicity of colon cancer-initiating cells in a xenograft mouse model. BMC Cancer, 2016, 16(1): 425.
19. Salim T, Sand-Dejmek J, Sjölander A. The inflammatory mediator leukotriene D4 induces subcellular β-catenin translocation and migration of colon cancer cells. Exp Cell Res, 2014, 321(2): 255-266.
20. Savari S, Vinnakota K, Zhang Y, et al. Cysteinyl leukotrienes and their receptors: bridging inflammation and colorectal cancer. World J Gastroenterol, 2014, 20(4): 968.
21. Heise CE, O'Dowd BF, Figueroa DJ, et al. Characterization of the human cysteinyl leukotriene 2 receptor. J Biol Chem, 2000, 275(39): 30531-30536.
22. Hu H, Chen G, Zhang J, et al. Distribution of cysteinyl leukotriene receptor 2 in human traumatic brain injury and brain tumors. Acta Pharmacol Sin, 2005, 26(6): 685-690.
23. Lynch KR, O'neill GP, Liu Q, et al. Characterization of the human cysteinyl leukotriene CysLT1 receptor. Nature, 1999, 399(6738): 789-793.
24. Mita H, Hasegawa M, Saito H, et al. Levels of cysteinyl leukotriene receptor mRNA in human peripheral leucocytes: significantly higher expression of cysteinyl leukotriene receptor 2 mRNA in eosinophils. Clin Exp Allergy, 2001, 31(11): 1714-1723.
25. Jiang W, Hall SR, Moos MPW, et al. Endothelial cysteinyl leukotriene 2 receptor expression mediates myocardial ischemia-reperfusion injury. Am J Pathol, 2008, 172(3): 592-602.
26. Chen L, Yang Y, Li CT, et al. CysLT2 receptor mediates lipopolysaccharide-induced microglial inflammation and consequent neurotoxicity in vitro. Brain Res, 2015, 1624: 433-445.
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