LI Bing 1 , YANG Yuanli 1 , JIA Yeran 2 , CAO Feng 1 , CHEN Ronglin 1 , ZHANG Hongxuan 2
  • 1. Department of Critical Care Medicine, Longgang Central Hospital of Shenzhen City, Shenzhen, Guangdong 518116, P. R. China;
  • 2. Eastern Section, Guangdong General Hospital, Guangdong Institute of Geriatrics, Guangzhou, Guangdong 510180, P. R. China;
ZHANG Hongxuan, Email: 13602816365@139.com
Tracheotomy; Weaning from mechanical ventilation; Respiratory humidification treatment apparatus; Clinical efficacy
10.7507/1671-6205.201807028
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Objective To investigate the clinical efficacy of AIRVO2 respiratory humidification apparatus in patients with tracheotomy after successful weaning from mechanical ventilation in intensive care unit (ICU).Methods One hundred subjects were randomly divided into a control group (treated with the tracheotomy mask joint oxygen inhalation by heating humidifier, n=50) and an observation group (treated with AIRVO2 model, n=50) on the basis of conventional therapy. Blood gas indexes (pH, PaO2, PaCO2, PaO2/FiO2) and clinical data (heart rate, respiratory rate, SpO2, sputum viscosity) were recorded at 0 h, 6 h, 12 h, 24 h, 48 h, 72 h after weaning. Besides, the incidence of postoperative pulmonary infection, rapid shallow breathing index (RSBI), successful weaning rate from mechanical ventilation and daily cost of weaning between the two groups were compared at 72 h after weaning.Results After treatment, all observed data of the patients were obviously improved compared with those before treatment. The differences of humidification effects between the observation group and the control group at the same time point were statistically significant (P<0.05). The differences of heart rate, respiratory rate, and SpO2 between the observation group and the control group at the same time point were statistically significant (P<0.05). The improvement of PaO2 and PaCO2 at the same time point were statistically different between the observation group and the control group (P<0.05). Seventy-two hours after weaning, the incidence of postoperative pulmonary infection and RSBI in the observation group were significantly lower than those in the control group (P<0.05), successful weaning rate from mechanical ventilation in the observation group was significantly higher than that in the control group (P<0.05), and the average daily cost of weaning from mechanical ventilation in the observation group was lower than that in the control group (P<0.05). Nine patients in the control group and 1 patient in the observation group needed secondary mechanical ventilation due to hypoxemia.Conclusion The therapy of AIRVO2 respiratory humidification apparatus combined with conventional treatment may achieve satisfactory effect for patients of successful weaning from mechanical ventilation with tracheotomy, and it is worthy of promotion in clinical use.

Citation： LI Bing, YANG Yuanli, JIA Yeran, CAO Feng, CHEN Ronglin, ZHANG Hongxuan. Clinical efficacy of using respiratory humidification apparatus (AIRVO2) in patients with tracheotomy after successful weaning from mechanical ventilation. Chinese Journal of Respiratory and Critical Care Medicine, 2019, 18(1): 37-41. doi: 10.7507/1671-6205.201807028 Copy

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