CHENG Yanqiuzi 1 , SU Zhuquan 1 , WU Zhilong 2 , ZHANG Peize 3 , CHEN Weisheng 4 , ZHOU Ziqing 1 , LUO Weizhan 1 , GUO Wenliang 1 , CHEN Xiaobo 1 , SUN Wan 1 , LI Shiyue 1
  • 1. Department of Respiratory Medicine, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong 510120, P. R. China;
  • 2. Department of Tuberculosis, The Fourth People’s Hospital of Foshan, Foshan, Guangdong 528041, P. R. China;
  • 3. Second Department of Respiratory Medicine, The Third People’s Hospital of Shenzhen, Shenzhen, Guangdong 528041, P. R. China;
  • 4. Department of Tuberculosis, The Third People’s Hospital of Shantou, Shantou, Guangdong 515073, P. R. China;
LI Shiyue, Email: lishiyue@188.com
Tracheobronchial tuberculosis; Tracheobronchial stenosis; Clinical characteristics
10.7507/1671-6205.201906002
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Objective To investigate the clinical characteristics of tracheobronchial stenosis due to tracheobronchial tuberculosis (TBTB).Methods We recruited all patients diagnosed as TBTB within one year from four centers of Guangdong province, southern China. The prevalence, risk factors and bronchoscopy characteristics of tracheobronchial stenosis were analyzed. The location and pathological type of stenosis were also compared between different genders.Results A total of 345 patients were diagnosed with TBTB, 206 cases (59.7%) of which were concomitant with varying degrees of tracheobronchial stenosis. The stenosis was mainly located at upper lobe (50.0%) and gave priority to unilateral infiltration. The proportion of left and right-side stenosis were 53.9% and 44.2%, respectively. Forty-nine cases (23.8%) with tracheobronchia stenosis developed severe airway narrowing, the proportion of which was similar between left and right-side lung (49% vs. 51%). Severe stenosis in the left-side lung mainly involved in upper lobe (37.5%), main bronchus (37.5%) and the right-side mainly involved in upper lobe (44.0%), middle lobe or intermediate bronchus (40.0%). Among the TBTB patients, females, those with age ≥18 years, non-smokers, and those with symptom duration ≥4 weeks were more likely to be with tracheobronchial stenosis (P<0.05). The differences in gender between the patients with airway stenosis were as follows: the median age of female tracheobronchial stenosis patients was smaller than that of male patients (31 years vs. 43 years, P<0.05); stenosis were more likely involved in left side and main bronchus in female patients; ulceration necrosis of stenosis was more frequently seen in the female patients (P<0.05).Conclusions Tracheobronchial stenosis due to tracheobronchial tuberculosis is more frequently seen in young and middle-aged female patients. There are different stenosis location and lesion types between different genders.

Citation： CHENG Yanqiuzi, SU Zhuquan, WU Zhilong, ZHANG Peize, CHEN Weisheng, ZHOU Ziqing, LUO Weizhan, GUO Wenliang, CHEN Xiaobo, SUN Wan, LI Shiyue. Clinical characteristics of tracheobronchial stenosis due to tracheobronchial tuberculosis. Chinese Journal of Respiratory and Critical Care Medicine, 2020, 19(4): 379-383. doi: 10.7507/1671-6205.201906002 Copy

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