Objective To investigate the epidemiological characteristics of the first cluster of patients with coronavirus diseases 2019 (COVID-19) in Gansu.Methods All 6 COVID-19 patients from a non-familial cluster in Gansu, were extracted from Gansu Provincial Health Information System until Feb 20, 2020. The patients were confirmed by nucleic acid detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The analyses were included via retrospective method: patient clinical characteristics, the summary of epidemiology, and CT image characteristics.Results This clustered outbreak was the first non-family clustered outbreak in Gansu after traveled to Thailand. All 6 COVID-19 confirmed patients were a kindergarten staff in Gansu, aged from 26 to 51 years, and were female. They traveled to Thailand in the same period, and had the same epidemiological exposure history. They were diagnosed as COVID-19 by transnasopharyngeal swab real-time fluorescent reverse transcription-PCR for SARS-CoV-2 nucleic acid examination at different time points after return to Gansu. The first patient was ill on January 21, 2020, with fever as first symptom. She was diagnosed at the Xigu District People’s Hospital in Lanzhou and was transferred to Lanzhou Pulmonary Hospital after being diagnosed. She was cured with one week’s antiviral treatment. The remaining 5 patients were treated in Longxi People’s Hospital. The common clinical symptoms were fever, throat discomfort, headache, and fatigue. Through 7 to 10 days’ antiviral treatment, they all were cured. All patients belonged to common type and had good prognosis.Conclusion The COVID-19 patients in a non-familial cluster have the same epidemiological history. Early medical observation, SARS-CoV-2 nucleic acid examination and comprehensive chest CT should be arranged promptly to make diagnosis and give responsive treatment, so that the prognosis is often good.
Citation:
WANG Xiaojun, WEN Hengjun, WANG Xiaobo, YANG Pengjun, GAO Jing, LIU Hua. Analysis of the first non-familial cluster of patients with coronavirus disease 2019 in Gansu. Chinese Journal of Respiratory and Critical Care Medicine, 2020, 19(2): 172-175. doi: 10.7507/1671-6205.202002121
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- 1. 国家卫生健康委办公厅 国家中医药管理局办公室. 新型冠状病毒感染的肺炎诊疗方案 (试行第六版)(EB/OL). http://www.nhc.gov.cn/yzygj/s7653p/202002/8334a8326dd94d329df351d7da8aefc2.shtml [2020-02-19].
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- 3. Benvenuto D, Giovannetti M, Ciccozzi A, et al. The 2019-new coronavirus epidemic: evidence for virus evolution[J/OL]. J Med Virol, 2020 -01-29. https://onlinelibrary.wiley.com/doi/abs/10.1002/jmv.25688.
- 4. Wang DW, Hu B, Hu C, et al. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus–infected pneumonia in Wuhan, China[J/OL]. JAMA, 2020 -02-07. https://jamanetwork.com/journals/jama/fullarticle/2761044.
- 5. Huang CL, Wang YM, Li XW, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China[J/OL]. Lancet, 2020-01-24. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30183-5/fulltext.
- 6. Chan JFW, Yuan SF, Kok KH, et al. A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster[J/OL]. lancet, 2020-01-24. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30154-9/fulltext.
- 7. 白少丽, 王建云, 周莹荃, 等 . 甘肃省首起新型冠状病毒肺炎家庭聚集性疫情分析[J/OL] . 中华预防医学杂志 , 2020 -02-20. http://www.pubhealth.org.cn/cn/wxshow.asp?id=6393&yxfb=y.