• 1. Graduate Department of Xi'an Physical Education University, Xi'an, Shannxi 710068, P. R. China;
  • 2. Department of Rehabilitation Medicine, The Second Affiliated Hospital of the Air Force Military Medical University, Xi'an, Shannxi 710032, P. R. China;
  • 3. School of Sports and Health Sciences, Xi'an Physical Education University, Xi'an, Shannxi 710068, P. R. China;
WANG Gang, Email: wanggang778@126.com
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Objective  To systematic investigate whether phase angle of bioelectrical impedance is associated with the functionality, severity, and prognosis of individuals afflicted with chronic obstructive pulmonary disease (COPD). Methods  Relevant literature from the PubMed, Embase, Web of Science, Scopus, CNKI, and WanFang databases was retrieved, and literature screening and data extraction in accordance with standardized methods were conducted. Literature quality was assessed by utilizing Mixed Methods Appraisal Tool. Subsequently, data pertaining to the results was extracted for summarization and induction, and descriptive analyzed through qualitative synthesis. Results  A total of 11 studies, encompassing 2189 subjects, were included in this review, and the overall quality of the literature was deemed relatively high. Of these studies, three examined the correlation between phase angle and the severity of COPD, eight studies examined the correlation between phase angle and pulmonary and physical function in COPD, and seven studies reported the association between phase angle and adverse outcomes such as hospitalization time, nutritional risk, acute exacerbation and mortality in COPD. The collective findings suggestted that reduced levels of phase angle are linked to severe illness, diminished function, and unfavorable prognosis among individuals with COPD. Phase angle emerged as an independent predictor of lung function, physical exercise endurance, acute exacerbation and mortality in COPD patients. Conclusion  The phase angle level of COPD patients is associated with their disease severity, function, and prognosis, and is an potential available indicator for clinical management of COPD patients.

Citation: HOU Shuanglong, WEI Jiaxin, ZHAO Xin, WANG Gang. The phase angle and chronic obstructive pulmonary disease: a systematic review. Chinese Journal of Respiratory and Critical Care Medicine, 2024, 23(5): 312-320. doi: 10.7507/1671-6205.202312004 Copy

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