Objective To investigate the incidence of urolithiasis in the children who ingested milk powder tainted with melamine in the Chengdu area.
Methods A total of 5 795 infants were screened for urolithiasis by ultrasound examination from September 17, 2008 to December 9, 2008. The data were analyzed using SPSS 13.0 software.
Results Twenty-four children were diagnosed with urolithiasis with an incidence of 0.41%, including 12 males and 12 females. The mean age of those children with urolithiasis was 2.35±1.68 years old. No significant difference was shown in the incidence of urolithiasis between males and females (P gt;0.05). The incidence of urolithiasis in the infants aged 0-3 was significantly higher than that in the children who were more than 3 years old (P lt;0.05).
Conclusion The incidence of urolithiasis in the infants aged 0-3 in Chengdu and the surrounding areas is relatively high. Further data should be collected during the follow-up of these cases.
Citation：
LI Maojun,ZHANG Rong,ZHAO Juan,LI Yunbi,YUE Linxian,LU Man,CHEN Changhui. Investigation on the Incidence of Urolithiasis in Children Who Ingested Milk Powder Tainted with Melamine in Chengdu Area. Chinese Journal of Evidence-Based Medicine, 2009, 09(6): 632-634. doi: 10.7507/1672-2531.20090114
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Copyright © the editorial department of Chinese Journal of Evidence-Based Medicine of West China Medical Publisher. All rights reserved
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胡世莲, 吴蕾, 陈尹, 等. 安徽中部地区食用含三聚氰胺超标奶粉婴幼儿泌尿系统结石发病情况调查. 中国循证医学杂志, 2008, 8(12): 1039-1042.
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- 1. 叶章群. 泌尿系结石研究现况与展望. 中华实验外科杂志, 2005, 22(3): 261-262.
- 2. 2008年9月13日, 卫生部办公厅关于印发《与食用受污染三鹿牌婴幼儿配方奶粉相关的婴幼儿泌尿系统结石诊疗方案》的通知. 卫生部医政司. http://www.moh.gov.cn/publicfiles/business/htmlfiles/mohyzs/s3586/200809/37772.htm.
- 3. Burns K. Recall shines spotlight on pet foods. J Am Vet Med Assoc, 2007, 230: 1285-1288.
- 4. Thomas R, Kulkarni GU. A hydrogen bonded channel structure formed by a complex of uracil and melamine. Beilstein J Org Chem, 2007, 3: 17.
- 5. 林祥梅, 王建峰, 等. 三聚氰胺的毒性研究. 毒理学杂志, 2008, 22(3): 216-217.
- 6. Ronald E. Baynes, Geof Smith, et al. Pharmacokinetics of melamine in pigs following intravenous administration. Food and Chemical Toxicology, 46(2008): 1196-1200.
- 7. Buur JL, Baynes RE, Riviere JE. Estimating meat withdrawal times in pigs exposed to melamine contaminated feed using a physiologically based pharmacokinetic model. Regulatory Toxicology and Pharmacology, 2008, 51: 324-331.
- 8. Okumara M, Hasegawa R, Shirai T, et al. Relationship between calculus formation and carcinogenesis in the urinary bladder of rats admistered the non-genotoxic agents thymine and melamine.Carcinogenesis, 1992, 13(6): 1043-1045.
- 9. 胡世莲, 吴蕾, 陈尹, 等. 安徽中部地区食用含三聚氰胺超标奶粉婴幼儿泌尿系统结石发病情况调查. 中国循证医学杂志, 2008, 8(12): 1039-1042.
