Application of netmeta Package in R Language to Implement Network Meta-Analysis_Chinese Journal of Evidence-Based Medicine

Authors：

 ZHANGChao ¹ , GENGPei-liang ² , GUOYi ³ ,  ZENGXian-tao ^1,4

1. Center for Evidence-based Medicine and Clinical Research, Taihe Hospital, Hubei University of Medicine, Shiyan 442000, China;
2. Cancer Center, Division of Internal Medicine, Chinese PLA General Hospital & Chinese PLA Medical School, Beijing 100853, China;
3. Department of Epidemiology, School of Public Health, Wuhan University, Wuhan 430071, China;
4. Department of Stomatology, Taihe Hospital, Hubei University of Medicine, Shiyan 442000, China;

Corresponding author：

ZENGXian-tao, Email: zengxiantao1128@163.com

Keywords：

Network meta-analysis; Bayesian; Frequentist; netmeta package; R language

DOI：

10.7507/1672-2531.20140103

Video：

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Abstract Full text Figures/Tables Video References Cited by

The netmeta package is specialized for implementing network meta-analysis. This package was developed based on the theories of classical frequentist under R language framework. The netmeta package overcomes some difficulties of the software and/or packages based on the theories of Bayesian, for these software and/or packages need to set prior value when conducting network meta-analysis. The netmeta package also has the advantages of simple operation process and ease to operate. Moreover, this package can calculate and present the individual matched and pooled results based on the random and fixed effect model at the same time. It also can draw forest plots. This article gives a briefly introduction to show the process to conduct network meta-analysis using netmeta package.

Citation： ZHANGChao, GENGPei-liang, GUOYi, ZENGXian-tao. Application of netmeta Package in R Language to Implement Network Meta-Analysis. Chinese Journal of Evidence-Based Medicine, 2014, 14(5): 625-630. doi: 10.7507/1672-2531.20140103 Copy

1.	曾宪涛, 曹世义, 孙凤, 等. Meta分析系列之六:间接比较及网状分析.中国循证心血管医学杂志, 2012(05):399-402.
2.	Lumley T. Network meta-analysis for indirect treatment comparisons. Stat Med, 2002, 21(16):2313-24.
3.	曾宪涛, 张超, 郭毅. R软件R2WinBUGS程序包在网状Meta分析中的应用.中国循证医学杂志, 2013, 13(9):1137-1144.
4.	张超, 董圣杰, 曾宪涛. R软件gemtc程序包在网状Meta分析中的应用.中国循证医学杂志, 2013, 13(10):1258-1264.
5.	曾宪涛, 徐畅, 张超, 等.网状Meta分析在Stata软件中的实现.中国循证医学杂志, 2013, 13(11):1387-1391.
6.	张超, 孙凤, 曾宪涛. R调用JAGS软件实现网状Meta分析.中国循证医学杂志, 2014, 14(2):241-248.
7.	张超, 牛玉明, 曾宪涛. R软件nlme程序包在网状Meta分析中的应用.中国循证医学杂志, 2014, 14(3):355-360.
8.	罗杰, 张超, 曾宪涛. R软件调用OpenBUGS软件实现网状Meta分析.中国循证医学杂志, 2014, 14(4):492-496.
9.	Gerta Ruecker GS. netmeta:Network meta-analysis with R. Available at: http://cran.r-project.org/web/packages/netmeta/netmetapdf.2013-08-01.
10.	Jonas DE, Wilkins TM, Bangdiwala S, et al. Findings of Bayesian Mixed Treatment Comparison Meta-Analyses:Comparison and Exploration Using Real-World Trial Data and Simulation[Internet]. Rockville (MD):Agency for Healthcare Research and Quality (US); [2013 Feb. Appendix A, WinBUGS Code Used in Bayesian Mixed Treatment Comparisons Meta-Analysis. Available from: http://www.ncbi.nlm.nih.gov/books/NBK126104/.
11.	董圣杰, 曾宪涛, 郭毅. R软件Metafor程序包在Meta分析中的应用.中国循证医学杂志. 2012, 12(9):1141-1147.
12.	蒋文瀚, 陈炳为, 郑建光, 等. R语言meta包在Meta分析中的应用.循证医学, 2011, 11(5):305-309.
13.	张超, 徐畅, 曾宪涛.网状Meta分析中网状关系图的绘制.中国循证医学杂志, 2013, 13(11):1382-1386.

1. 曾宪涛, 曹世义, 孙凤, 等. Meta分析系列之六:间接比较及网状分析.中国循证心血管医学杂志, 2012(05):399-402.
2. Lumley T. Network meta-analysis for indirect treatment comparisons. Stat Med, 2002, 21(16):2313-24.
3. 曾宪涛, 张超, 郭毅. R软件R2WinBUGS程序包在网状Meta分析中的应用.中国循证医学杂志, 2013, 13(9):1137-1144.
4. 张超, 董圣杰, 曾宪涛. R软件gemtc程序包在网状Meta分析中的应用.中国循证医学杂志, 2013, 13(10):1258-1264.
5. 曾宪涛, 徐畅, 张超, 等.网状Meta分析在Stata软件中的实现.中国循证医学杂志, 2013, 13(11):1387-1391.
6. 张超, 孙凤, 曾宪涛. R调用JAGS软件实现网状Meta分析.中国循证医学杂志, 2014, 14(2):241-248.
7. 张超, 牛玉明, 曾宪涛. R软件nlme程序包在网状Meta分析中的应用.中国循证医学杂志, 2014, 14(3):355-360.
8. 罗杰, 张超, 曾宪涛. R软件调用OpenBUGS软件实现网状Meta分析.中国循证医学杂志, 2014, 14(4):492-496.
9. Gerta Ruecker GS. netmeta:Network meta-analysis with R. Available at: http://cran.r-project.org/web/packages/netmeta/netmetapdf.2013-08-01.
10. Jonas DE, Wilkins TM, Bangdiwala S, et al. Findings of Bayesian Mixed Treatment Comparison Meta-Analyses:Comparison and Exploration Using Real-World Trial Data and Simulation[Internet]. Rockville (MD):Agency for Healthcare Research and Quality (US); [2013 Feb. Appendix A, WinBUGS Code Used in Bayesian Mixed Treatment Comparisons Meta-Analysis. Available from: http://www.ncbi.nlm.nih.gov/books/NBK126104/.
11. 董圣杰, 曾宪涛, 郭毅. R软件Metafor程序包在Meta分析中的应用.中国循证医学杂志. 2012, 12(9):1141-1147.
12. 蒋文瀚, 陈炳为, 郑建光, 等. R语言meta包在Meta分析中的应用.循证医学, 2011, 11(5):305-309.
13. 张超, 徐畅, 曾宪涛.网状Meta分析中网状关系图的绘制.中国循证医学杂志, 2013, 13(11):1382-1386.

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