CHENYao-long 1,2,3 # , YAOLiang 1,2,3 # , DULiang 4 , ZENGXian-tao 5 , WEIDang 1,2,3 , WANGQi 1,2,3 , WANGXiao-qin 1,2,3 , YANGKe-hu 1,2,3
  • 1. Key Laboratory of Evidence-based Medicine and Knowledge Translation of Gansu Province, Lanzhou 730000, China;
  • 2. Evidence-based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou 730000, China;
  • 3. Chinese GRADE Center, Lanzhou University, Lanzhou 730000, China;
  • 4. Chinese Evidence-Based Medicine Center, West China Hospital, Sichuan University, Chengdu 610041, China;
  • 5. Center for Evidence-based Medicine and Translational Research, Zhongnan Hospital, Wuhan University, Wuhan 430071, China;
YANGKe-hu, Email: yangkh@lzu.edu.cn
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Depending on different designs of original studies, systematic reviews of diagnostic studies could be categorized into two kinds:one is based on diagnostic randomized controlled trials, of which the GRADE rating approach is similar to that of interventional systematic reviews; and the other is based on diagnostic accuracy tests, of which the GRADE rating approach is introduced in this article. This article explains the application of GRADE in systematic reviews of diagnostic accuracy tests mainly from the angle of theoretical analysis, including rationales, methods, and challenges.

Citation: CHENYao-long, YAOLiang, DULiang, ZENGXian-tao, WEIDang, WANGQi, WANGXiao-qin, YANGKe-hu. Rationales, Methods, Challenges and Development Tendency of Using GRADE in Systematic Reviews of Diagnostic Accuracy Tests. Chinese Journal of Evidence-Based Medicine, 2014, 14(11): 1402-1406. doi: 10.7507/1672-2531.20140225 Copy

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