LINan 1 , YAOLiang 2,3 , WUQiong-fang 4 , WEIDang 2,3 , WANGQi 2,3 , WANGXiao-qin 2,3 , YANGKe-hu 2,3 , CHENYao-long 2,3
  • 1. Second Affiliated Hospital of Lanzhou University, Lanzhou 730000, China;
  • 2. Evidence-based Medicine Center/Chinese GRADE Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou 730000, China;
  • 3. Key Laboratory of Clinical Translational Research and Evidence-based Medicine of Gansu Province, Lanzhou 730000, China;
  • 4. First Affiliated Hospital of Lanzhou University, Lanzhou 730000, China;
CHENYao-long, Email: chenyaolong21@163.com
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Objective To evaluate the quality of Chinese clinical practice guidelines published in domestic medical journals from 2012 to 2013 and compare with the quality of guidelines published before. Methods CNKI, CBM and WanFang Data were searched to collect guidelines from January 1st, 2012 to December 31st, 2013. Two reviewers independently screened literature according to the inclusion and exclusion criteria and extracted data. The AGREE Ⅱ instrument was applied to assess methodological quality of included guidelines. Results A total of 78 guidelines were identified. Among them, 37 guidelines were published in 2012, and 41 in 2013. The scores of 6 domains' scores of AGREE Ⅱ were as follows:scope and purpose (24%), stakeholder involvement (11%), rigour of development (7%), clarity of presentation (32%), applicability (7%), and editorial independence (4%). The results of subgroup analysis indicated that, the scores in 5 domains (except applicability) of the guidelines published in CSCD journals were higher than those of non CSCD journals; the scores in 4 domains (except stakeholder involvement and applicability) of the guidelines received funds were higher than those of guidelines with no funds; and the scores in 5 domains (except editorial independence) of the guidelines published in 2013 were higher than those in 2012. Conclusion The guidelines published from 2012 to 2013 have higher quality than guidelines published before 2012, but great discrepancies exist when comparing with international guidelines of average level. Chinese guidelines developers should attach importance to international methodology to develop guidelines, and use the AGREE Ⅱ instrument to develop and report guidelines.

Citation: LINan, YAOLiang, WUQiong-fang, WEIDang, WANGQi, WANGXiao-qin, YANGKe-hu, CHENYao-long. Quality Evaluation of Clinical Practice Guidelines Published in Journals of Mainland China during 2012-2013. Chinese Journal of Evidence-Based Medicine, 2015, 15(3): 259-263. doi: 10.7507/1672-2531.20150045 Copy

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