A Comparative Study of Essential Medicines Lists for Children of WHO, India, South Africa and National Essential Medicine List of China_Chinese Journal of Evidence-Based Medicine

Authors：

 LIUDan ^1,2,3 ^# ,  CHENGJing ⁴ ^# ,  ZHANGLing-li ^1,2 , LIYou-ping ⁵ , ZENGLi-nan ^1,2 , ZHANGChuan ^1,2

1. Department of Pharmacy/Evidence-Based Pharmacy Centre, West China Second University Hospital, Sichuan University, Chengdu 610041, China;
2. Key Laboratory of Birth Defects and Related Diseases of Women and Children(Sichuan University), Ministry of Education, Chengdu 610041, China;
3. West China School of Pharmacy, Sichuan University, Chengdu 610041, China;
4. Sichuan Essential medicines procurement service center, Chengdu 610041, China;
5. Chinese Cochrane Centre and Chinese Evidence-Based Medicine Centre, West China Hospital, Sichuan University, Chengdu 610041, China;

Corresponding author：

ZHANGLing-li, Email: zhanglingli@scu.edu.cn

Keywords：

Essential medicine list; Essential medicine list for children; Comparative study

DOI：

10.7507/1672-2531.20150067

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

Objective Comparing the worldwide Essential Medicines Lists for Children (EMLcs) and National Essential Medicine List (NEML) of China (2012 edition), to provide evidence for establishing EMLc of China. Method We searched the official websites of WHO and Ministry of Health of some countries to identify published EMLcs. We compared the situation of updating, the number and classification of medicines, and the dosage forms between these EMLcs and NEML of China (2012). Result By August 2013, the WHO, India and South Africa had established EMLc. The number of medicines of NEML of China (2012) ranked first in the four lists. The WHO, India and China classified the medicines by pharmacologic action, while South Africa classified it by anatomical therapeutic chemical (ATC) classification. Except the WHO, India, South Africa and China did not have specific medicines for neonatal care or medicines for diseases of joints. The main administration routes in these four lists were oral administration, injection, and topical application. There were medicine restrictions in EMLcs of WHO and India, while no medicine restrictions in lists of South Africa and China. Conclusion Medicines listed in NEML of China (2012) do not match children's disease burden of China. The applicable dosage forms for children are few and the medicine restrictions are absent for the list. So this list is not suitable for Children.

Citation： LIUDan, CHENGJing, ZHANGLing-li, LIYou-ping, ZENGLi-nan, ZHANGChuan. A Comparative Study of Essential Medicines Lists for Children of WHO, India, South Africa and National Essential Medicine List of China. Chinese Journal of Evidence-Based Medicine, 2015, 15(4): 393-402. doi: 10.7507/1672-2531.20150067 Copy

1.	WHO. Essential medicine. Available at:http://www.who.int/medicines/services/essmedicines_def/en/.
2.	张川, 王莉, 袁强, 等. 我国基本药物目录、基本医疗保险药物目录和WHO基本药物目录比较. 中国循证医学杂志, 2009, 9 (7):765-773.
3.	张伶俐, 张川, 梁毅, 等. 我国2009版基本药物目录(基层)与WHO 2010版儿童基本药物示范目录比较分析. 中国循证医学杂志, 2010, 10 (9):1027-1036.
4.	WHO. WHO Model List of Essential Medicines for Children 4^th list (April 2013) Available at:http://www.who.int/medicines/publications/essentialmedicines/4th_EMLc_FINAL_web_8Jul13.pdf.
5.	Indian Academy of Pediatrics. Indian Academy of Pediatrics List of Essential Medicines for Children of India First List-October 2011. Available at:http://www.iapindia.org/files/IAP%20EMLc%20October%2031.pdf.
6.	The National Department of Health, Pretoria, South Africa. Standard treatment guidelines and essential drugs list for South Africa hospital level paediatrics 2006 edition. Available at:http://www.kznhealth.gov.za/chrp/documents/Guidelines/Guidelines%20National/EDL%20Paediatrics/EDL%20Paediatrics%20Hospital%20Level%202006.pdf.
7.	胡仪吉, 金有豫, 主编. 第1版. 中国国家处方集(化学药品与生物制品卷·儿童版). 北京:人民军医出版社, 2013.
8.	WHO. South Africa Statistics. Available at:http://www.who.int/countries/zaf/en/.
9.	WHO. India Statistics. Available at:http://www.who.int/countries/ind/en/.
10.	WHO. China Statistics. Available at:http://www.who.int/countries/chn/zh/index.Html.
11.	GBD. Global Burden of Disease Study 2010-China Results by Cause 1990-2010. Available at:http://ghdx.healthmetricsandevaluation.org/global-burden-disease-study-2010-gbd-2010-data-downloads.
12.	GBD. Global Burden of Disease Study 2010-India Results by Cause 1990-2010. Available at:http://ghdx.healthmetricsandevaluation.org/global-burden-disease-study-2010-gbd-2010-data-downloads.
13.	GBD. Global Burden of Disease Study 2010-South Africa Results by Cause 1990-2010. Available at:http://ghdx.healthmetricsandevaluation.org/global-burden-disease-study-2010-gbd-2010-data-downloads.
14.	Murray CJL, Ezzati M, Flaxman AD, et al. GBD 2010:design, defnitions, and metrics. Lancet, 2012, 380(9859):2063-2066.
15.	王莉, 周帮旻, 宋佳佳, 等. 25国基本药物目录循证评价. 中国循证医学杂志, 2009, 9(7):754-764.
16.	WHO. Guidelines for ATC classification and DDD assignment 2013. Available at:http://www.whocc.no/filearchive/publications/1_2013guidelines.pdf.
17.	Unedited Report of the 19^th WHO Expert Committee on the Selection and Use of Essential Medicines (including the 18th WHO Model List of Essential Medicines and the 4^th WHO Model List of Essential Medicinesfor Children). Available at:http://www.who.int/medicines/EC19uneditedReport.pdf.
18.	卫生部. 国家基本药物目录(2012年版)相关政策问答. Available at:http://www.moh.gov.cn/mohywzc/s3582/201303/57a7b9ead4074247b9f9bf31a137689b.shtml.
19.	WHO Technical Report Series 958 The selection and use of essential medicines Report of the WHO Expert Committee, 2009 (including the 16th WHO Model List of Essential Medicines and the 2nd WHO Model List of Essential Medicines for Children). Available at:http://whqlibdoc.who.int/trs/WHO_TRS_958_eng.pdf.
20.	WHO technical report series 950 the selection and use of essential medicines Report of the WHO Expert Committee,October 2007 (including the Model List of Essential Medicines). Available at:http://whqlibdoc.who.int/trs/WHO_TRS_950_eng.pdf.
21.	WHO. Medicines:medicines for children. Available at:http://www.who.int/mediacentre/factsheets/fs341/en/index.html.
22.	张伶俐, 李幼平, 胡蝶, 等. 我国儿童药物短缺的现状分析. 中国循证医学杂志, 2012, 12(10):1159-1164.

Chinese Journal of Evidence-Based Medicine

A Comparative Study of Essential Medicines Lists for Children of WHO, India, South Africa and National Essential Medicine List of China

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Next Article

Format

Content