Risk Factors of Anesthesia Management in Postoperative Headache Induced by Thyroidectomy: A Case-Control Study_Chinese Journal of Evidence-Based Medicine

Authors：

 TANWen-fei , SHIYue ,  FANGBo , MAHong

Department of Anesthesiology, the First Hospital of China Medical University, Shenyang 110001, China;

Corresponding author：

FANGBo, Email: drunk0630@126.com

Keywords：

Thyroidectomy; Postoperative headache; Flurbiprofen axetil; Case-control study

DOI：

10.7507/1672-2531.20150084

Video：

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Objective To investigate the risk factors of perioperative anaesthesia management in postoperative headache induced by thyroidectomy. Methods A 1:1 age and operation time matched case-control design study was performed. General anesthesia patients for elective thyroidectomy with postoperative headache (case group, VAS score >4) and without postoperative headache (control group, VAS score ≤4) were recruited. Univariate and multivariate analyses were performed to analyze the risk factors of postoperative headache after 24 and 48 hours of operation by using SPSS 18.0 software. Results A total of 134 patients were included; of which, 67 were in the case group and the other 67 were in the control group. The results of univariate analysis showed that female and administration of flurbiprofen axetil might be the risk factors of postoperative headache. The further multivariate analysis showed that administration of flurbiprofen axetil was significantly associated with decreased postoperative headache (OR=0.387, 95%CI 0.185 to 0.811). Conclusion Perioperative anesthesia management has a certain influence on postoperative headache induced by thyroidectomy. The use of flurbiprofen axetil during operation could reduce the incidence rate of postoperative headache.

Citation： TANWen-fei, SHIYue, FANGBo, MAHong. Risk Factors of Anesthesia Management in Postoperative Headache Induced by Thyroidectomy: A Case-Control Study. Chinese Journal of Evidence-Based Medicine, 2015, 15(5): 500-502. doi: 10.7507/1672-2531.20150084 Copy

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11.	陈竞文, 宋陆军. 甲状腺癌的流行病学新特点. 中国临床医学, 2009, 16(5):812-813.
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13.	马艳辉, 吴洁, 张瑛, 等. 氟比洛芬酯复合舒芬太尼用于下肢骨科术后静脉镇痛的效果. 上海医学, 2013, 36(2):158-160.
14.	陈红, 王玉, 曹文超, 等. 氟比洛芬酯术后镇痛对神经外科患者内皮素水平的影响. 临床麻醉学杂志, 2013, 29(1):60-61.
15.	Su C, Su Y, Chou CW, et al. Intravenous flurbiprofen for post-thymectomy pain relief in patients with myasthenia gravis. J Cardiothorac Surg, 2012, 7(21):98.
16.	Yamashita K, Fukusaki M, Ando Y, et al. Preoperative administration of intravenous flurbiprofen axetil reduces postoperative pain for spinal fusion surgery. J Anesth, 2006, 20(2):92-95.
17.	蒋新, 李莉. 体位干预减轻甲状腺手术患者不适效果观察. 蚌埠医学院学报, 2009, 34(7):638-639.
18.	李莉, 黄丽华, 刘美平, 等. 术前体位训练预防甲状腺手术体位综合征的临床观察. 中国实用护理杂志, 2007, 23(2):27-28.
19.	徐翔, 李义贤. 氟比洛芬酯预防头颈外科手术术后疼痛的应用研究. 中国实用医药, 2014, 9(12):126-127.

1. 陈曦, 李宏为. 当今甲状腺外科手术的特点. 外科理论与实践, 2012, (1):1-3.
2. 王敬美, 孙翠梅, 苏娟. 甲状腺手术后头枕部疼痛的预防与护理. 中国实用护理杂志, 2006, 22(32):27-28.
3. 卜淑娟, 黄夏蕾, 方文. 甲状腺手术前头低肩高体位练习时间的研究. 护士进修杂志, 2005, 20(7):593-594.
4. 庄春柳, 黄步英, 陈燕珠, 等. 适时体位干预及改进体位垫在甲状腺手术病人中的应用探讨. 护理研究, 2005, 19(8):692-693.
5. 林建玲, 邓洁娜, 青毅, 等. 舒适体位在全麻甲状腺手术的临床观察. 中国医药导报, 2012, 9(15):184-185.
6. 孙淑琴, 杨瑞华, 吕哲. 甲状腺手术术前颈仰卧位练习的临床意义. 黑龙江医学, 2001, 25(8):609.
7. 范鹰, 闫朝岐, 张一娜. 甲状腺手术体位对患者术后头痛和呕吐症状及精神心理状态的影响. 中国临床康复, 2005, 9(20):66-67.
8. 陈涛. 甲状腺术后头痛的原因浅析. 中国临床医学, 2005, 12(3):460.
9. 杨成林, 王小强. 甲状腺术后头痛及预防. 现代肿瘤医学, 2007, 15(6):851-852.
10. Han DW, Koo BN, Chung WY, et al. Preoperative greater occipital nerve block in total thyroidectomy patients can reduce postoperative occipital headache and posterior neck pain. Thyroid, 2006, 16(6):599-603.
11. 陈竞文, 宋陆军. 甲状腺癌的流行病学新特点. 中国临床医学, 2009, 16(5):812-813.
12. 贺纯静, 聂浩雄, 郭春芮, 等. 氟比洛芬酯术后镇痛对老年髋关节置换术患者术后认知功能的影响. 临床麻醉学杂志, 2013, 29(1):13-15.
13. 马艳辉, 吴洁, 张瑛, 等. 氟比洛芬酯复合舒芬太尼用于下肢骨科术后静脉镇痛的效果. 上海医学, 2013, 36(2):158-160.
14. 陈红, 王玉, 曹文超, 等. 氟比洛芬酯术后镇痛对神经外科患者内皮素水平的影响. 临床麻醉学杂志, 2013, 29(1):60-61.
15. Su C, Su Y, Chou CW, et al. Intravenous flurbiprofen for post-thymectomy pain relief in patients with myasthenia gravis. J Cardiothorac Surg, 2012, 7(21):98.
16. Yamashita K, Fukusaki M, Ando Y, et al. Preoperative administration of intravenous flurbiprofen axetil reduces postoperative pain for spinal fusion surgery. J Anesth, 2006, 20(2):92-95.
17. 蒋新, 李莉. 体位干预减轻甲状腺手术患者不适效果观察. 蚌埠医学院学报, 2009, 34(7):638-639.
18. 李莉, 黄丽华, 刘美平, 等. 术前体位训练预防甲状腺手术体位综合征的临床观察. 中国实用护理杂志, 2007, 23(2):27-28.
19. 徐翔, 李义贤. 氟比洛芬酯预防头颈外科手术术后疼痛的应用研究. 中国实用医药, 2014, 9(12):126-127.

Chinese Journal of Evidence-Based Medicine

Risk Factors of Anesthesia Management in Postoperative Headache Induced by Thyroidectomy: A Case-Control Study

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