When investing the relationship between independent and dependent variables in dose-response meta-analysis, the common method is to fit a regression function. A well-established model should take both linear and non-linear relationship into consideration. Traditional linear dose-response meta-analysis model showed poor applicability since it was based on simple linear function. We introduced a piecewise linear function into dose-response meta-analysis model which overcame this problem. In this paper, we will give a detailed discussion on traditional linear and piecewise linear regression model in dose-response meta-analysis.
Citation： YUYun-xiang, ZHANGChao, WENGHong, KuangXin-ying, GONGTai-fang, LUYun, XUChang. How to Conduct Dose-response Meta-analysis by Using Linear relation and Piecewise Linear Regression Model. Chinese Journal of Evidence-Based Medicine, 2016, 16(1): 111-114. doi: 10.7507/1672-2531.20160020 Copy