Effects of Silver Ions Dressing for Diabetic Foot Ulcers: A Randomized Controlled Trial_Chinese Journal of Evidence-Based Medicine

Authors：

 HEWan-qiang , LUOWei-hua , LILei , JIANGLiang

Department of Burns and Plastic Surgery, Dazhou Central Hospital, Dazhou 635000, China;

Corresponding author：

Keywords：

Diabetic foot; ulcer; Silver ions dressing; Randomized controlled trial

DOI：

10.7507/1672-2531.20160079

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Objective To investigate the clinical therapeutic effect of silver ions dressing for patient with diabetic foot ulcers. Methods According to the diagnostic and classification criteria of diabetes and diabetic foot of World Health Organization (WHO), outpatients and inpatients with diabetic foot ulcers admitted to the Department of Burns and Plastic Surgery of Dazhou Central Hospital from October 2013 to May 2015 were randomly divided into a silver ion dressing treatment group and a traditional dressing treatment group. The effective rate, time of occurrence of granulation tissue, wound healing time and wound area reduction ratio between the two groups were compared by using SPSS17.0 software. Results A total of 80 patients were included, of which 40 patients in each group. Compared with the control group, the total effective rate was higher (92.5% vs. 62.5%, P=0.001), the occurrence time of granulation tissue (6.4±0.72 vs. 10.8 ±1.9, P=0.000) and wound healing time (31.3±8.2 vs. 47.4±11.5, P=0.000) were shorter, and the wound area reduction ration was greater (46.3±7.6 vs. 32.6±6.1, P=0.000) in the silver ions dressing group with significant differences. Conclusion The effects of silver-containing dressings is superior to Vaseline dressing in the treatment of diabetic foot ulcers.

Citation： HEWan-qiang, LUOWei-hua, LILei, JIANGLiang. Effects of Silver Ions Dressing for Diabetic Foot Ulcers: A Randomized Controlled Trial. Chinese Journal of Evidence-Based Medicine, 2016, 16(5): 510-512. doi: 10.7507/1672-2531.20160079 Copy

1.	Noor S, Zubair M, Ahmad J. Diabetic foot ulcer——A review on pathophysiology, classification and microbial etiology. Diabetes Metab Syndr, 2015, 9(3): 192-199.
2.	Charles PG, Uçkay I, Kressmann B, et al. The role of anaerobes in diabetic foot infections. Anaerobe, 2015, 34: 8-13.
3.	李梅, 周珑, 张鹤. 银离子敷料在普外科换药中的应用研究及进展. 临床普外科电子杂志, 2014, 2(1): 45-47.
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6.	唐蕾, 陈亚文, 赵千隽. 银离子抗菌敷料应用于糖尿病足患者的临床观察. 上海护理, 2009, 9(6): 50-51.
7.	宋瑞捧, 沈珂珂, 马豪莉, 等. 表皮生长因子联合银离子敷料治疗糖尿病足感染的临床研究. 中华医院感染学杂志, 2014, 24(16): 4033-4035.
8.	谌静, 陈盛业. 新换药方法治疗糖尿病足的临床观察. 疾病监测与控制, 2014, 24(16): 792-793.
9.	邱吉苗, 谢翠华, 李春荣. 含银离子敷料治疗糖尿病足溃疡50例. 广东医学2007, 28(3): 472.
10.	郭春兰, 邓红艳. 含银敷料辅助治疗糖尿病足溃疡感染的效果观察. 华西医学 2014, 29(9): 1611-1614.
11.	周艳斌, 陈友华. 银离子敷料治疗糖尿病足伤口效果观察. 护理学杂志, 2015, 25(15): 86.
12.	陈志雄. 银离子敷料联合水凝胶治疗糖尿病足的效果观察. 现代医院, 2015,15(3): 82-83.
13.	向英, 张恒术, 邹静, 等. 创新敷料治疗糖尿病足溃疡的临床研究. 中国药房, 2012, 23(22): 2063-2064.
14.	李旭亚, 丁惠萍. 糖尿病足感染伤口治疗中使用银离子敷料的临床观察. 护理实践与研究, 2009, 6(20): 34-35.
15.	何书连, 李晓燕. 湿性敷料在糖尿病足换药护理中的应用. 现代预防医学, 2012, 39(15): 4020-4021.

1. Noor S, Zubair M, Ahmad J. Diabetic foot ulcer——A review on pathophysiology, classification and microbial etiology. Diabetes Metab Syndr, 2015, 9(3): 192-199.
2. Charles PG, Uçkay I, Kressmann B, et al. The role of anaerobes in diabetic foot infections. Anaerobe, 2015, 34: 8-13.
3. 李梅, 周珑, 张鹤. 银离子敷料在普外科换药中的应用研究及进展. 临床普外科电子杂志, 2014, 2(1): 45-47.
4. Uçkay I, Aragón-Sánchez J, Lew D, et al. Diabetic Foot Infections: What have we learned in the last 30 years? Int J Infect Dis, 2015, 40: 81-91.
5. 刘仁海, 高霞. 含银离子敷料治疗2-3级糖尿病足溃疡42例. 中国药业, 2012, 21(9): 50-51.
6. 唐蕾, 陈亚文, 赵千隽. 银离子抗菌敷料应用于糖尿病足患者的临床观察. 上海护理, 2009, 9(6): 50-51.
7. 宋瑞捧, 沈珂珂, 马豪莉, 等. 表皮生长因子联合银离子敷料治疗糖尿病足感染的临床研究. 中华医院感染学杂志, 2014, 24(16): 4033-4035.
8. 谌静, 陈盛业. 新换药方法治疗糖尿病足的临床观察. 疾病监测与控制, 2014, 24(16): 792-793.
9. 邱吉苗, 谢翠华, 李春荣. 含银离子敷料治疗糖尿病足溃疡50例. 广东医学2007, 28(3): 472.
10. 郭春兰, 邓红艳. 含银敷料辅助治疗糖尿病足溃疡感染的效果观察. 华西医学 2014, 29(9): 1611-1614.
11. 周艳斌, 陈友华. 银离子敷料治疗糖尿病足伤口效果观察. 护理学杂志, 2015, 25(15): 86.
12. 陈志雄. 银离子敷料联合水凝胶治疗糖尿病足的效果观察. 现代医院, 2015,15(3): 82-83.
13. 向英, 张恒术, 邹静, 等. 创新敷料治疗糖尿病足溃疡的临床研究. 中国药房, 2012, 23(22): 2063-2064.
14. 李旭亚, 丁惠萍. 糖尿病足感染伤口治疗中使用银离子敷料的临床观察. 护理实践与研究, 2009, 6(20): 34-35.
15. 何书连, 李晓燕. 湿性敷料在糖尿病足换药护理中的应用. 现代预防医学, 2012, 39(15): 4020-4021.

Chinese Journal of Evidence-Based Medicine

Effects of Silver Ions Dressing for Diabetic Foot Ulcers: A Randomized Controlled Trial

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