Demands of Dosage Forms and Specifications of Essential Medicines for Children in Different Levels of Medical Institutions in China: A Cross-sectional Survey_Chinese Journal of Evidence-Based Medicine

Authors：

 HUZhi-qiang ^1,2,3,4 ,  ZHANGLing-li ^1,2,3 ,  LIYou-ping ⁵ , WANChao-min ⁶ , QUANShu-yan ^1,2,3,4 , ZENGLi-nan ^1,2,3 , JIANGLu-can ^1,2,3,4 , GUIGe ^1,2,3,4

1. Department of Pharmacy, West China Second University Hospital, Sichuan University, Chengdu 610041, China;
2. Evidence-Based Pharmacy Center, West China Second University Hospital, Sichuan University, Chengdu 610041, China;
3. Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu 610041, China;
4. West China School of Pharmacy, Sichuan University, Chengdu 610041, China;
5. Chinese Evidence-based Medicine Center, West China Hospital, Sichuan University, Chengdu 610041, China;
6. Department of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu 610041, China;

Corresponding author：

ZHANGLing-li, Email: zhlingli@sina.com; LIYou-ping, Email: yzmylab@hotmail.com

Keywords：

Medical institution; Children; Essential medicine; Dosage form; Specifications; Demand; Cross-sectional survey

DOI：

10.7507/1672-2531.20160096

Video：

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Objective To investigate and compare the demands of dosage forms and specifications of essential medicine for children in different levels of medical institutions, so as to provide references for selection of essential medicines for children by levels of medical institutions. Methods In 13 provinces or municipalities, 104 medical institutions, including tertiary, secondary and primacy medical institutions, were investigated by questionnaires. Kinds of drugs, dosage forms, requirement types and requirement levels of drugs were analyzed and compared in different levels of medical institutions. Results Tertiary medical institutions had higher demands than other levels of medical institutions for the number of drugs types, dosage forms and level of demand on each drug (P < 0.05), secondary medical institutions were higher than primacy medical institutions (P < 0.05), but community health service centers were the same as township health centers. Conclusion The demands of dosage forms and specifications of essential medicine for children in different levels of medical institutions are different. So future studies should develop the essential medicines list for children depend on different levels of care.

Citation： HUZhi-qiang, ZHANGLing-li, LIYou-ping, WANChao-min, QUANShu-yan, ZENGLi-nan, JIANGLu-can, GUIGe. Demands of Dosage Forms and Specifications of Essential Medicines for Children in Different Levels of Medical Institutions in China: A Cross-sectional Survey. Chinese Journal of Evidence-Based Medicine, 2016, 16(6): 621-627. doi: 10.7507/1672-2531.20160096 Copy

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2.	WHO. WHO Model Lists of Essential Medicines. Available at: http://www.who.int/medicines/publications/essentialmedicines/en/.
3.	WHO. WHO Policy Perspectives on Medicines - The Selection of Essential Medicines. 2002.
4.	王莉, 周帮曼, 宋佳佳, 等. 25国基本药物目录循证评价. 中国循证医学杂志, 2009, 9(7): 754-764.
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6.	陈晶, 聂青, 刘妍. 《WHO基本药物示范目录》与我国《国家基本药物目录》动态调整程序比较与借鉴. 中国药房, 2015(3): 289-293.
7.	药物政策与基本药物制度司. 2012年版《国家基本药物目录》发布. Available at: http://www.moh.gov.cn/mohywzc/s3582/201303/b058a4edf14e4dc9a1f6f0f0c71a2cce.shtml.
8.	刘丹, 程静, 张伶俐, 等. WHO、印度、南非儿童基本药物目录与中国2012版基本药物目录的比较研究. 中国循证医学杂志, 2015, (4): 393-402.
9.	李友佳, 杨世民. 《国家基本药物目录》儿童用药分析及思考. 中国药事, 2014, 28(4): 349-353.
10.	钱丽萍, 马亚娜, 张莹. 我国儿童基本药物政策框架设计. 中国药房, 2014, 25(12): 1060-1062.
11.	李幼平, 沈建通. 基本药物目录遴选与使用的发展与创新. 中国循证医学杂志, 2013, 13(11): 1273-1279.
12.	Walid Bin Hosain. 孟加拉国及其他国家基本药物政策对中国的启示. 复旦大学, 2009.
13.	徐文娟. 我国基本药物目录及其实施现况. 复旦大学, 2012.
14.	全淑燕, 张伶俐, 李幼平等. 我国儿童急需但缺乏的基本药物剂型和规格的遴选. 中国循证医学杂志, 2016, 16(5): 497-504.
15.	米术斌, 张雷, 段一娜, 等. SPSS软件进行随机区组设计非参数检验的多重比较. 现代预防医学, 2009, 36(2): 217-219.
16.	李晓松. 医学统计学. 北京：高等教育出版社, 2008.
17.	郭春彦, 王晓玲. 我国儿童药物剂型和规格的现状. 儿科药学杂志, 2013, 19(8): 53-55.
18.	张伶俐, 李幼平, 胡蝶, 等. 我国儿童药物短缺的现状分析. 中国循证医学杂志, 2012, 12(10): 1159-1164.
19.	国家卫生和计划生育委员会. 关于保障儿童用药的若干意见. Available at: http://www.mohrss.gov.cn/SYrlzyhshbzb/ldbk/shehuibaozhang/yiliao/201406/t20140605_131493.htm.
20.	Medicines and Healthcare Products Regulatory Agency (MHRA).Department of health strategy on medicines for children. 2004.

1. World Health Assembly. Resolution WHA 28.66. Geneva: World Health Organization, 1975.
2. WHO. WHO Model Lists of Essential Medicines. Available at: http://www.who.int/medicines/publications/essentialmedicines/en/.
3. WHO. WHO Policy Perspectives on Medicines - The Selection of Essential Medicines. 2002.
4. 王莉, 周帮曼, 宋佳佳, 等. 25国基本药物目录循证评价. 中国循证医学杂志, 2009, 9(7): 754-764.
5. 车明凤, 韩白石. 我国颁布实施国家基本药物目录的概况. 中国药事, 2000, 14(1): 19-21.
6. 陈晶, 聂青, 刘妍. 《WHO基本药物示范目录》与我国《国家基本药物目录》动态调整程序比较与借鉴. 中国药房, 2015(3): 289-293.
7. 药物政策与基本药物制度司. 2012年版《国家基本药物目录》发布. Available at: http://www.moh.gov.cn/mohywzc/s3582/201303/b058a4edf14e4dc9a1f6f0f0c71a2cce.shtml.
8. 刘丹, 程静, 张伶俐, 等. WHO、印度、南非儿童基本药物目录与中国2012版基本药物目录的比较研究. 中国循证医学杂志, 2015, (4): 393-402.
9. 李友佳, 杨世民. 《国家基本药物目录》儿童用药分析及思考. 中国药事, 2014, 28(4): 349-353.
10. 钱丽萍, 马亚娜, 张莹. 我国儿童基本药物政策框架设计. 中国药房, 2014, 25(12): 1060-1062.
11. 李幼平, 沈建通. 基本药物目录遴选与使用的发展与创新. 中国循证医学杂志, 2013, 13(11): 1273-1279.
12. Walid Bin Hosain. 孟加拉国及其他国家基本药物政策对中国的启示. 复旦大学, 2009.
13. 徐文娟. 我国基本药物目录及其实施现况. 复旦大学, 2012.
14. 全淑燕, 张伶俐, 李幼平等. 我国儿童急需但缺乏的基本药物剂型和规格的遴选. 中国循证医学杂志, 2016, 16(5): 497-504.
15. 米术斌, 张雷, 段一娜, 等. SPSS软件进行随机区组设计非参数检验的多重比较. 现代预防医学, 2009, 36(2): 217-219.
16. 李晓松. 医学统计学. 北京：高等教育出版社, 2008.
17. 郭春彦, 王晓玲. 我国儿童药物剂型和规格的现状. 儿科药学杂志, 2013, 19(8): 53-55.
18. 张伶俐, 李幼平, 胡蝶, 等. 我国儿童药物短缺的现状分析. 中国循证医学杂志, 2012, 12(10): 1159-1164.
19. 国家卫生和计划生育委员会. 关于保障儿童用药的若干意见. Available at: http://www.mohrss.gov.cn/SYrlzyhshbzb/ldbk/shehuibaozhang/yiliao/201406/t20140605_131493.htm.
20. Medicines and Healthcare Products Regulatory Agency (MHRA).Department of health strategy on medicines for children. 2004.

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Demands of Dosage Forms and Specifications of Essential Medicines for Children in Different Levels of Medical Institutions in China: A Cross-sectional Survey

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