Correlation between Metabolic Syndrome and Arterial Stiffness in Elderly People: A Population-based Study in Communities of Northern Shanghai_Chinese Journal of Evidence-Based Medicine

Authors：

 QINYan-li , WANGKai , LVYu-yan , XIONGJing , BAIBin , YUShi-kai , ZHOUYi-wu , CHIChen ,  ZHANGYi , XUYa-wei

Department of Cardiology, No. 10 Hospital, Tongji University, Shanghai 200072, China;

Corresponding author：

ZHANGYi, Email: yizshcn@gmail.com

Keywords：

Elderly; Arteriosclerosis; Metabolic syndrome; Pulse wave velocity; Population study

DOI：

10.7507/1672-2531.20160172

Video：

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Objective To investigate the association between metabolic syndrome and arterial stiffness in elderly people. Methods 1 599 participants aged over 65 years old were recruited from 10 communities located in the northern Shanghai. Carotid-femoral pulse wave velocity (cf-PWV) of each participant was measured by SphygmoCor device. Measurements for the diagnosis of metabolic syndrome were all investigated for each participant. SPSS 20.0 was used for data management and statistical analysis. Results Cf-PWV was significantly associated with metabolic syndrome and its diagnostic measurements (P<0.001). Moreover, with the accumulating diagnostic measurements, cf-PWV increased gradually and significantly. The increasing trend remained significant in all participants, in men and in women (P<0.001). Conclusion Arterial stiffness is significantly associated with metabolic syndrome and the accumulation of its diagnostic measurements.

Citation： QINYan-li, WANGKai, LVYu-yan, XIONGJing, BAIBin, YUShi-kai, ZHOUYi-wu, CHIChen, ZHANGYi, XUYa-wei. Correlation between Metabolic Syndrome and Arterial Stiffness in Elderly People: A Population-based Study in Communities of Northern Shanghai. Chinese Journal of Evidence-Based Medicine, 2016, 16(10): 1127-1130. doi: 10.7507/1672-2531.20160172 Copy

1.	王浩, 杨文. 老年代谢综合征患病情况及特点. 实用老年医学, 2003, 17(3): 142-149.
2.	Isomaa B, Almgren P, Tuomi T, et al. Cardiovascular morbidity and mortality associated with the metabolic syndrome. Diabetes Care, 2001, 24(4): 683-689.
3.	McNeill AM, Rosamond WD, Girman CJ, et al. The metabolic syndrome and 11-year risk of incident cardiovascular disease in the atherosclerosis risk in communities study. Diabetes Care, 2005, 28(2): 385-390.
4.	Laurent S, Boutouyrie P, Asmar R, et al. Aortic stiffness is an independent predictor of all-cause and cardiovascular mortality in hypertensive patients. Hypertension, 2001, 37(5): 1236-1241.
5.	谢晓亮, 李觉, 胡大一. 脉搏波传导速度测定方法及临床意义. 中国心血管病研究杂志, 2007, 5(6): 465-468.
6.	Mancia G, Laurent S, Agabiti-Rosei E, et al. Reappraisal of European guidelines on hypertension management: a European Society of Hypertension Task Force document. J Hypertens, 2009, 27(11): 2121-2158.
7.	Greenland P, Alpert J S, Beller G A, et al. 2010 ACCF/AHA guideline for assessment of cardiovascular risk in asymptomatic adults: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol, 2010, 56(25): e50-e103.
8.	Determinants of pulse wave velocity in healthy people and in the presence of cardiovascular risk factors: ‘establishing normal and reference values'. Eur Heart J, 2010, 31(19): 2338-2350.
9.	Laurent S, Cockcroft J, van BorteI L, et al. Expert consensus document on arterial stiffness methodological issues and clinical applications. Eur Heart J, 2006, 27(21): 2588-2605.
10.	唐世凡, 王朝晖, 董晓雁, 等. 代谢综合症与臂踝脉搏波速度的关系. 中国全科医学, 2015, 18(17): 2005-2009.
11.	刘淼, 何耀, 姜斌, 等. 北京某社区老年人群肱踝脉搏波传导速度与代谢综合症的现状研究. 北京大学学报(医学版), 2014, 46(3): 429-434.
12.	李建军. 代谢综合症组分数与肱踝脉搏波传导速度的相关性研究. 中国糖尿病杂志, 2014, 22(9): 793-795.
13.	曾莎, 张蕴, 孙宁. 老年代谢综合征及其组成成分与脉搏波传导速度关系. 天津医科大学学报, 2012, 18(3): 356-362.
14.	陈民, 李玉晓, 李莉, 等. 中年代谢综合征?糖尿病及糖尿病合并冠心病脉搏波传导速度?踝肱指数对比分析. 中国医药指南, 2012, 10(10): 98-100.
15.	郭远, 宝辉, 李卫, 等. 代谢综合征对老年糖尿病患者动脉僵硬度的影响. 中华老年心脑血管病杂志, 2011, 13(12): 1070-1072.
16.	Antonino Tuttolomondo, Domenico Di Raimondo, Riccardo Di Sciacca, et al. Arterial stiffness and ischemic stroke in subjects with and without metabolic syndrome. Atherosclerosis, 2012, 225: 216-219.
17.	Vlachopoulos C, Aznaouridis K, Stefanadis C. Prediction of Cardiovascular Events and All-Cause Mortality With Arterial Stiffness Systematic Review and Meta-Analysis. J Am Coll Cardiol, 2010, 55(13): 1318-1327.
18.	Shin JY, Lee HR, Lee DC. Increased arterial stiffness in healthy subjects with high-normal glucose levels and in subjects with pre-diabetes. Cardiovasc Diabetol, 2011, 10: 1-5.
19.	Kawamoto R, Tabara Y, Kusunoki T, et al. A slightly high-normal glucose level is associated with increased arterial stiffness in Japanese community-dwelling persons with pre-diabetes. Vasc Med, 2013, 18(5): 251-256.
20.	张艳芬, 佟伟军, 刘洋, 等. 代谢综合征与心脑血管病及死亡前瞻性队列研究. 中国公共卫生, 2013, 29(10): 1405-1409.
21.	王宏宇, 龚兰生, 张维中. 脉搏波传导速度测定的新认识. 国外医学-心血管疾病分册, 2000, 27(2): 70-72.

1. 王浩, 杨文. 老年代谢综合征患病情况及特点. 实用老年医学, 2003, 17(3): 142-149.
2. Isomaa B, Almgren P, Tuomi T, et al. Cardiovascular morbidity and mortality associated with the metabolic syndrome. Diabetes Care, 2001, 24(4): 683-689.
3. McNeill AM, Rosamond WD, Girman CJ, et al. The metabolic syndrome and 11-year risk of incident cardiovascular disease in the atherosclerosis risk in communities study. Diabetes Care, 2005, 28(2): 385-390.
4. Laurent S, Boutouyrie P, Asmar R, et al. Aortic stiffness is an independent predictor of all-cause and cardiovascular mortality in hypertensive patients. Hypertension, 2001, 37(5): 1236-1241.
5. 谢晓亮, 李觉, 胡大一. 脉搏波传导速度测定方法及临床意义. 中国心血管病研究杂志, 2007, 5(6): 465-468.
6. Mancia G, Laurent S, Agabiti-Rosei E, et al. Reappraisal of European guidelines on hypertension management: a European Society of Hypertension Task Force document. J Hypertens, 2009, 27(11): 2121-2158.
7. Greenland P, Alpert J S, Beller G A, et al. 2010 ACCF/AHA guideline for assessment of cardiovascular risk in asymptomatic adults: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol, 2010, 56(25): e50-e103.
8. Determinants of pulse wave velocity in healthy people and in the presence of cardiovascular risk factors: ‘establishing normal and reference values'. Eur Heart J, 2010, 31(19): 2338-2350.
9. Laurent S, Cockcroft J, van BorteI L, et al. Expert consensus document on arterial stiffness methodological issues and clinical applications. Eur Heart J, 2006, 27(21): 2588-2605.
10. 唐世凡, 王朝晖, 董晓雁, 等. 代谢综合症与臂踝脉搏波速度的关系. 中国全科医学, 2015, 18(17): 2005-2009.
11. 刘淼, 何耀, 姜斌, 等. 北京某社区老年人群肱踝脉搏波传导速度与代谢综合症的现状研究. 北京大学学报(医学版), 2014, 46(3): 429-434.
12. 李建军. 代谢综合症组分数与肱踝脉搏波传导速度的相关性研究. 中国糖尿病杂志, 2014, 22(9): 793-795.
13. 曾莎, 张蕴, 孙宁. 老年代谢综合征及其组成成分与脉搏波传导速度关系. 天津医科大学学报, 2012, 18(3): 356-362.
14. 陈民, 李玉晓, 李莉, 等. 中年代谢综合征?糖尿病及糖尿病合并冠心病脉搏波传导速度?踝肱指数对比分析. 中国医药指南, 2012, 10(10): 98-100.
15. 郭远, 宝辉, 李卫, 等. 代谢综合征对老年糖尿病患者动脉僵硬度的影响. 中华老年心脑血管病杂志, 2011, 13(12): 1070-1072.
16. Antonino Tuttolomondo, Domenico Di Raimondo, Riccardo Di Sciacca, et al. Arterial stiffness and ischemic stroke in subjects with and without metabolic syndrome. Atherosclerosis, 2012, 225: 216-219.
17. Vlachopoulos C, Aznaouridis K, Stefanadis C. Prediction of Cardiovascular Events and All-Cause Mortality With Arterial Stiffness Systematic Review and Meta-Analysis. J Am Coll Cardiol, 2010, 55(13): 1318-1327.
18. Shin JY, Lee HR, Lee DC. Increased arterial stiffness in healthy subjects with high-normal glucose levels and in subjects with pre-diabetes. Cardiovasc Diabetol, 2011, 10: 1-5.
19. Kawamoto R, Tabara Y, Kusunoki T, et al. A slightly high-normal glucose level is associated with increased arterial stiffness in Japanese community-dwelling persons with pre-diabetes. Vasc Med, 2013, 18(5): 251-256.
20. 张艳芬, 佟伟军, 刘洋, 等. 代谢综合征与心脑血管病及死亡前瞻性队列研究. 中国公共卫生, 2013, 29(10): 1405-1409.
21. 王宏宇, 龚兰生, 张维中. 脉搏波传导速度测定的新认识. 国外医学-心血管疾病分册, 2000, 27(2): 70-72.

Chinese Journal of Evidence-Based Medicine

Correlation between Metabolic Syndrome and Arterial Stiffness in Elderly People: A Population-based Study in Communities of Northern Shanghai

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