The risk factors of urolithiasis: a case-control study_Chinese Journal of Evidence-Based Medicine

Authors：

LIU Xingnian ¹ , XU Chang ^1,2 , ZHANG Chao ³ , LIU Tongzu ¹ ,  WANG Xinghuan ¹

1. Department of Urology, Zhongnan Hospital of Wuhan University, Wuhan, 430071, P.R.China;
2. Center for Evidence-Based and Translational Medicine, Wuhan University, Wuhan, 430071, P.R.China;
3. Center for Evidence-based Medicine and Clinical Research, Taihe Hospital, Hubei University of Medicine, Shiyan, 442000, P.R.China;

Corresponding author：

WANG Xinghuan, Email: wangxinghuan@whu.edu.cn

Keywords：

Urolithiasis; Risk factor; Case-control study

DOI：

10.7507/1672-2531.201606049

Video：

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Objective To investigate the correlation between smoking, alcohol, chronic diseases, fasting plasma glucose levels, uric acid and the incidence of urolithiasis. Methods A 1∶1 pair-wise matching design was used in case-control study. We randomly selected 150 samples from 459 patients with urolithiasis in Zhongnan Hospital of Wuhan University from May 2015 to November 2015. Patient with intact information were identified as case group. The control group were patients who hospitalized in the same period without urolithiasis matched by gender, ethnic, and marital status. Univariate ANOVA and multivariate conditional logistic regression were used to test the differences between the two groups. Results A total of 125 patients in case group and 125 patients in control group were included. The peak age of urolithiasis was 50 to 70 years old, male patients accounted for 70.75% of the population, and one side urolithiasis accounted for 62.24% of the stone types. The results of multivariate conditional logistic regression showed that hyperuricemia was the related factor of urolithiasis (OR=5.19, 95%CI 2.27 to 11.91, P<0.01). Conclusions Hyperuricemia is a high risk factor for urolithiasis.

Citation： LIU Xingnian, XU Chang, ZHANG Chao, LIU Tongzu, WANG Xinghuan. The risk factors of urolithiasis: a case-control study. Chinese Journal of Evidence-Based Medicine, 2017, 17(10): 1131-1134. doi: 10.7507/1672-2531.201606049 Copy

1.	那彦群, 叶章群, 孙颖浩, 等. 2014 版中国泌尿外科疾病诊断治疗指南. 北京: 人民卫生出版社, 2013: 129-165.
2.	Scales CD, Smith AC, Hanley JM, et al. Prevalence of kidney stones in the United States. Eur Urol, 2012, 62(1): 160-165.
3.	Türk C, Petřík A, Sarica K, et al. EAU guidelines on interventional treatment for urolithiasis. Eur Urol, 2016, 69(3): 475-482.
4.	张立峰, 方志辉, 靳勇, 等. 影响泌尿系结石的多因素研究. 黑龙江医药, 2015, 28(1): 170-172.0.
5.	周璠娅. 泌尿系结石患者发病危险因素调查研究. 河北医学, 2016, 22(3): 458-461.0.
6.	Pearle MS, Goldfarb DS, Assimos DG, et al. Medical management of kidney stones: AUA guideline. J Urol, 2014, 192(2): 316-324.
7.	孙振球, 徐勇. 医学统计学(第四版). 北京: 人民卫生出版社, 2014: 529-536.
8.	胡正委, 曹全富, 王洛夫, 等. 超重肥胖泌尿系结石患者 133 例结石成分分析. 现代泌尿外科杂志, 2017, 22(1): 25-28.0.
9.	殷晶晶, 谌卫, 丁家荣, 等. 糖尿病、高血压对肾结石患者首次发病年龄的影响. 国际泌尿系统杂志, 2012, 32(6): 763-767.0.
10.	陈希, 谌卫, 丁家荣, 等. 泌尿系结石患者血脂及相关影响因素的研究. 中国全科医学, 2011, 14(34): 3924-3926.0.
11.	王坚, 吴舟, 李普云. 上尿路结石与代谢. 河北医学, 2002, 8(5): 409-411.0.

1. 那彦群, 叶章群, 孙颖浩, 等. 2014 版中国泌尿外科疾病诊断治疗指南. 北京: 人民卫生出版社, 2013: 129-165.
2. Scales CD, Smith AC, Hanley JM, et al. Prevalence of kidney stones in the United States. Eur Urol, 2012, 62(1): 160-165.
3. Türk C, Petřík A, Sarica K, et al. EAU guidelines on interventional treatment for urolithiasis. Eur Urol, 2016, 69(3): 475-482.
4. 张立峰, 方志辉, 靳勇, 等. 影响泌尿系结石的多因素研究. 黑龙江医药, 2015, 28(1): 170-172.0.
5. 周璠娅. 泌尿系结石患者发病危险因素调查研究. 河北医学, 2016, 22(3): 458-461.0.
6. Pearle MS, Goldfarb DS, Assimos DG, et al. Medical management of kidney stones: AUA guideline. J Urol, 2014, 192(2): 316-324.
7. 孙振球, 徐勇. 医学统计学(第四版). 北京: 人民卫生出版社, 2014: 529-536.
8. 胡正委, 曹全富, 王洛夫, 等. 超重肥胖泌尿系结石患者 133 例结石成分分析. 现代泌尿外科杂志, 2017, 22(1): 25-28.0.
9. 殷晶晶, 谌卫, 丁家荣, 等. 糖尿病、高血压对肾结石患者首次发病年龄的影响. 国际泌尿系统杂志, 2012, 32(6): 763-767.0.
10. 陈希, 谌卫, 丁家荣, 等. 泌尿系结石患者血脂及相关影响因素的研究. 中国全科医学, 2011, 14(34): 3924-3926.0.
11. 王坚, 吴舟, 李普云. 上尿路结石与代谢. 河北医学, 2002, 8(5): 409-411.0.

Chinese Journal of Evidence-Based Medicine

The risk factors of urolithiasis: a case-control study

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