Objective
To investigate the correlation between smoking, alcohol, chronic diseases, fasting plasma glucose levels, uric acid and the incidence of urolithiasis.
Methods
A 1∶1 pair-wise matching design was used in case-control study. We randomly selected 150 samples from 459 patients with urolithiasis in Zhongnan Hospital of Wuhan University from May 2015 to November 2015. Patient with intact information were identified as case group. The control group were patients who hospitalized in the same period without urolithiasis matched by gender, ethnic, and marital status. Univariate ANOVA and multivariate conditional logistic regression were used to test the differences between the two groups.
Results
A total of 125 patients in case group and 125 patients in control group were included. The peak age of urolithiasis was 50 to 70 years old, male patients accounted for 70.75% of the population, and one side urolithiasis accounted for 62.24% of the stone types. The results of multivariate conditional logistic regression showed that hyperuricemia was the related factor of urolithiasis (OR=5.19, 95%CI 2.27 to 11.91, P<0.01).
Conclusions
Hyperuricemia is a high risk factor for urolithiasis.
Citation：
LIU Xingnian, XU Chang, ZHANG Chao, LIU Tongzu, WANG Xinghuan. The risk factors of urolithiasis: a case-control study. Chinese Journal of Evidence-Based Medicine, 2017, 17(10): 1131-1134. doi: 10.7507/1672-2531.201606049
Copy
Copyright © the editorial department of Chinese Journal of Evidence-Based Medicine of West China Medical Publisher. All rights reserved
| 1. |
那彦群, 叶章群, 孙颖浩, 等. 2014 版中国泌尿外科疾病诊断治疗指南. 北京: 人民卫生出版社, 2013: 129-165.
|
| 2. |
Scales CD, Smith AC, Hanley JM, et al. Prevalence of kidney stones in the United States. Eur Urol, 2012, 62(1): 160-165.
|
| 3. |
Türk C, Petřík A, Sarica K, et al. EAU guidelines on interventional treatment for urolithiasis. Eur Urol, 2016, 69(3): 475-482.
|
| 4. |
张立峰, 方志辉, 靳勇, 等. 影响泌尿系结石的多因素研究. 黑龙江医药, 2015, 28(1): 170-172.0.
|
| 5. |
周璠娅. 泌尿系结石患者发病危险因素调查研究. 河北医学, 2016, 22(3): 458-461.0.
|
| 6. |
Pearle MS, Goldfarb DS, Assimos DG, et al. Medical management of kidney stones: AUA guideline. J Urol, 2014, 192(2): 316-324.
|
| 7. |
孙振球, 徐勇. 医学统计学(第四版). 北京: 人民卫生出版社, 2014: 529-536.
|
| 8. |
胡正委, 曹全富, 王洛夫, 等. 超重肥胖泌尿系结石患者 133 例结石成分分析. 现代泌尿外科杂志, 2017, 22(1): 25-28.0.
|
| 9. |
殷晶晶, 谌卫, 丁家荣, 等. 糖尿病、高血压对肾结石患者首次发病年龄的影响. 国际泌尿系统杂志, 2012, 32(6): 763-767.0.
|
| 10. |
陈希, 谌卫, 丁家荣, 等. 泌尿系结石患者血脂及相关影响因素的研究. 中国全科医学, 2011, 14(34): 3924-3926.0.
|
| 11. |
王坚, 吴舟, 李普云. 上尿路结石与代谢. 河北医学, 2002, 8(5): 409-411.0.
|
- 1. 那彦群, 叶章群, 孙颖浩, 等. 2014 版中国泌尿外科疾病诊断治疗指南. 北京: 人民卫生出版社, 2013: 129-165.
- 2. Scales CD, Smith AC, Hanley JM, et al. Prevalence of kidney stones in the United States. Eur Urol, 2012, 62(1): 160-165.
- 3. Türk C, Petřík A, Sarica K, et al. EAU guidelines on interventional treatment for urolithiasis. Eur Urol, 2016, 69(3): 475-482.
- 4. 张立峰, 方志辉, 靳勇, 等. 影响泌尿系结石的多因素研究. 黑龙江医药, 2015, 28(1): 170-172.0.
- 5. 周璠娅. 泌尿系结石患者发病危险因素调查研究. 河北医学, 2016, 22(3): 458-461.0.
- 6. Pearle MS, Goldfarb DS, Assimos DG, et al. Medical management of kidney stones: AUA guideline. J Urol, 2014, 192(2): 316-324.
- 7. 孙振球, 徐勇. 医学统计学(第四版). 北京: 人民卫生出版社, 2014: 529-536.
- 8. 胡正委, 曹全富, 王洛夫, 等. 超重肥胖泌尿系结石患者 133 例结石成分分析. 现代泌尿外科杂志, 2017, 22(1): 25-28.0.
- 9. 殷晶晶, 谌卫, 丁家荣, 等. 糖尿病、高血压对肾结石患者首次发病年龄的影响. 国际泌尿系统杂志, 2012, 32(6): 763-767.0.
- 10. 陈希, 谌卫, 丁家荣, 等. 泌尿系结石患者血脂及相关影响因素的研究. 中国全科医学, 2011, 14(34): 3924-3926.0.
- 11. 王坚, 吴舟, 李普云. 上尿路结石与代谢. 河北医学, 2002, 8(5): 409-411.0.
Journal type citation(15)
| 1. | 金名初，贾洪涛，罗茂华，周浴，杨华. 十堰地区引起泌尿系结石的危险因素分析. 现代医学与健康研究电子杂志. 2024(13): 114-116 .  Baidu Scholar | |
| 2. | 李玲玉，李萍，李一帆. 循证护理的饮食营养认知评估在泌尿结石患者中的应用. 齐鲁护理杂志. 2023(10): 119-123 . Baidu Scholar | |
| 3. | 曹凤娇，白雪娇，侯秀娟. 高尿酸血症合并肾结石中医体质特点和基于LASSO回归的危险因素分析. 中医药导报. 2023(06): 106-110 . Baidu Scholar | |
| 4. | 刘鎏. 循证护理联合疼痛护理对泌尿系统结石患者术后疼痛及并发症的影响. 医学信息. 2023(19): 167-170 . Baidu Scholar | |
| 5. | 马双钰，凯买尔丁·阿布都艾尼，陈巍，周晓辉，王玉杰. 老年泌尿系统结石患者的危险因素分析. 新疆医科大学学报. 2022(02): 176-179 . Baidu Scholar | |
| 6. | 胡赛峰，胡安定，钱挺照，胡春. KIM-1表达水平对高尿酸肾结石患者CR、UREA、GFR、Cys-C的影响. 全科医学临床与教育. 2022(02): 116-118+126 . Baidu Scholar | |
| 7. | 路玉霞. 基于ODSF的自我管理健康教育视频在泌尿系结石术后双J管留置患者中的护理效果. 山西卫生健康职业学院学报. 2021(01): 100-102 . Baidu Scholar | |
| 8. | 尹相林，姚嵩坡，李兴洲，沈萍，展秀君，张淑红，白雪，侯庆泽，关宝生，邱洪斌. 痛风和高尿酸血症发病的危险因素. 中国老年学杂志. 2020(10): 2041-2044 . Baidu Scholar | |
| 9. | 徐媛玉，潘铁军. 泌尿系结石合并高尿酸血症的相关因素及中医证型研究. 华南国防医学杂志. 2020(04): 247-249 . Baidu Scholar | |
| 10. | 金静，李雪莉. 以循证理论为基础的疼痛护理对泌尿系统结石手术患者术后功能恢复、疼痛程度与睡眠质量的影响. 护理实践与研究. 2020(15): 80-82 . Baidu Scholar | |
| 11. | 覃天资，黄群. 高尿酸血症与肾非尿酸结石相关研究进展. 右江民族医学院学报. 2019(01): 107-110 . Baidu Scholar | |
| 12. | 李生辉，柴雪，程庆水，卓栋，宋帅帅，王建帮，程浪，黄后宝. 某院2008—2017年泌尿系结石病例分析. 右江民族医学院学报. 2019(02): 187-189 . Baidu Scholar | |
| 13. | 宋凌菁，林媛珍，叶帆. 延续护理降低泌尿系结石术后复发率的研究. 实用临床医学. 2018(04): 83-85 . Baidu Scholar | |
| 14. | 霍振清，罗后宙，梁冰，朱家利，汪溢，姚泽钦. 固肾益气排石协定方对经皮肾镜碎石术后残留结石的治疗效果. 中华中医药学刊. 2018(09): 2277-2280 . Baidu Scholar | |
| 15. | 申恩瑞，彭惠，陈青，朱静，王冀岚，权彤彤，李玉美，殷水泽，马世武. 停用吡嗪酰胺对初治结核病患者血尿酸水平的影响. 广东医学. 2018(24): 3701-3705 . Baidu Scholar | |
Other types of references(6)
| 1. | 吴伟璇. 高尿酸血症合并超重/肥胖影响因素分析与体质分布[D]. 广州中医药大学. 2021. Baidu Scholar | |
| 2. | 申恩瑞. 停用吡嗪酰胺对初治结核病患者血尿酸水平的影响[D]. 南方医科大学. 2019. Baidu Scholar | |
| 3. | 王欢. 单中心结石相关梗阻性肾病发生与转归的临床研究[D]. 中国人民解放军海军军医大学. 2018. Baidu Scholar | |
| 4. | 张汉荣，高清河，杨镇有，罗辉. 中国成人泌尿系结石相关危险因素的Meta分析. 中华泌尿外科杂志. 2018(12): 935-939 . Baidu Scholar | |
| 5. | 范春艳. 泌尿系结石患者健康促进生活方式量表的构建与应用[D]. 苏州大学. 2021. Baidu Scholar | |
| 6. | 覃天资. 血尿酸水平对肾结石患者尿液KIM-1、NGAL及β2-MG生成的影响[D]. 右江民族医学院. 2019. Baidu Scholar | |
