Drug usage and costs of pneumonia inpatients in Karamay Central Hospital in 2014_Chinese Journal of Evidence-Based Medicine

Authors：

ZHANG Shengzhao ¹ , YU Jiajie ² ,  LIU Jianhong ¹ ,  LI Youping ² , ZHANG Weidong ¹ , XU Ting ³ , WU Min ¹ , LU Jing ³ , ZHAO Junfang ¹ , SUN Xin ² , SU Guanyue ²

1. Department of Pharmacy, Karamay Central Hospital, Karamay, 834000, P.R.China;
2. Chinese Evidence-Based Medicine Center, West China Hospital, Sichuan University, Chengdu, 610041, P.R.China;
3. Department of Pharmacy, West China Hospital, Sichuan University, Chengdu, 610041, P.R.China;

Corresponding author：

LIU Jianhong, Email: liuxyf001@126.com; LI Youping, Email: yzmylab@hotmail.com

Keywords：

Inpatients; Single disease; Pneumonia; Evidence-based pharmacy; Rational drug use

DOI：

10.7507/1672-2531.201608043

Video：

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Objective To investigate drug usage and costs of pneumonia inpatients in Karamay Central Hospital in 2014 and to provide baseline for evidence-based pharmacy study of single disease in respiratory system. Methods The information of drug use and expenditure of pneumonia inpatients were collected from the hospital information system (HIS). We analyzed the data including frequency, proportion and cumulative proportion by Excel 2007 software. Results A total of 309 inpatients were included, among the 78.96% were more than 60 years old. Among the antibiotics single therapy, the frequency of cefoperazone and sulbactam was the highest. Among the antibiotics combination therapy, the frequency of β-lactam antibiotics was the highest. Conclusion Pneumonia inpatients in Karamay Central Hospital are mainly older patients. The β-lactam antibiotics is used most in clinical practice.

Citation： ZHANG Shengzhao, YU Jiajie, LIU Jianhong, LI Youping, ZHANG Weidong, XU Ting, WU Min, LU Jing, ZHAO Junfang, SUN Xin, SU Guanyue. Drug usage and costs of pneumonia inpatients in Karamay Central Hospital in 2014. Chinese Journal of Evidence-Based Medicine, 2017, 17(8): 880-883. doi: 10.7507/1672-2531.201608043 Copy

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13.	赵春江, 张菲菲, 王占伟, 等. 2012 年中国成人社区获得性呼吸道感染主要致病菌耐药性的多中心研究. 中华结核和呼吸杂志, 2015, 38(1): 18-22.
14.	Liu Y, Ye X, Zhang H, et al. Antimicrobial susceptibility of Mycoplasma pneumoniae isolates and molecular analysis of macrolide-resistant strains from Shanghai, China. Antimicrob Agents Chemother, 2009, 53(5): 2160-2162.
15.	尹玉东, 曹彬, 王辉, 等. 北京地区成人社区获得性肺炎患者中肺炎支原体耐药情况的多中心调查. 中华结核和呼吸杂志, 2013, 36(12): 954-958.
16.	尹玉东, 曹彬. 社区获得性肺炎诊治指南解读: 从病情严重度分层角度. 中国循证医学杂志, 2015, 15(7): 756-760.
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1. Fine MJ, Smith MA, Carson CA, et al. Prognosis and outcomes of patients with community-acquired pneumonia. JAMA, 1996, 275(2): 134-141.
2. 中华医学会呼吸病学分会. 中国成人社区获得性肺炎诊断和治疗指南 (2016 年版). 中华结核和呼吸杂志, 2016, 39(4): 253-279.
3. 刘慧, 肖新才, 陆建云, 等. 2009-2012 年广州市社区获得性肺炎流行特征和病原学研究. 中华预防医学杂志, 2013, 47(12): 1089-1094.
4. 《抗菌药物临床应用指导原则》修订工作组. 抗菌药物临床应用指导原则 (2015 年版). 北京: 人民卫生出版社, 2015: 1-20.
5. Miyashita N, Matsushima T, Oka M. The JRS guidelines for the management of community-acquired pneumonia in adults: an update and new recommendations. Intern Med, 2006, 45(7): 419-428.
6. Corrêa-Rde A, Lundgren FL, Pereira-Silva JL, et al. Brazilian guidelines for community-acquired pneumonia in immunocompetent adults - 2009. J Bras Pneumol, 2009, 35(6): 574-601.
7. Wiersinga WJ, Bonten MJ, Boersma WG, et al. SWAB /NVALT (Dutch Working Party on Antibiotic Policy and Dutch Association of Chest Physicians) guidelines on the management of community-acquired pneumonia in adults. Neth J Med, 2012, 70(2): 90-101.
8. Mandell LA, Wunderink RG, Anzueto A, et al. Infectious Diseases Society of America/American Thoracic Society consensus guidelines on the management of community-acquired pneumonia in adults. Clin Infect Dis, 2007, 44(Suppl 2): 27-72.
9. Bartlett JG, Dowell SF, Mandell LA, et al. Practice guidelines for the management of community-acquired pneumonia in adults. Infectious Diseases Society of America. Clin Infect DIS, 2000, 31(2): 347-382.
10. Tao LL, Hu BJ, He LX, et al. Etiology and antimicrobial resistance of community-acquired pneumonia in adults patients in China. Chin Med J, 2012, 125(17): 2967-2972.
11. 刘又宁, 陈民均, 赵铁梅, 等. 中国城市成人社区获得性肺炎 665 例病原学多中心调查. 中华结核和呼吸杂志, 2006, 29(1): 3-8.
12. 王辉, 刘亚丽, 陈民均, 等. 2009-2010 年中国六城市成人社区获得性呼吸道感染病原菌耐药性监测. 中华结核和呼吸杂志, 2012, 35(2): 113-119.
13. 赵春江, 张菲菲, 王占伟, 等. 2012 年中国成人社区获得性呼吸道感染主要致病菌耐药性的多中心研究. 中华结核和呼吸杂志, 2015, 38(1): 18-22.
14. Liu Y, Ye X, Zhang H, et al. Antimicrobial susceptibility of Mycoplasma pneumoniae isolates and molecular analysis of macrolide-resistant strains from Shanghai, China. Antimicrob Agents Chemother, 2009, 53(5): 2160-2162.
15. 尹玉东, 曹彬, 王辉, 等. 北京地区成人社区获得性肺炎患者中肺炎支原体耐药情况的多中心调查. 中华结核和呼吸杂志, 2013, 36(12): 954-958.
16. 尹玉东, 曹彬. 社区获得性肺炎诊治指南解读: 从病情严重度分层角度. 中国循证医学杂志, 2015, 15(7): 756-760.
17. Mills GD, Oehley MR, Arrol B. Effectiveness of β lactam antibiotics compared with antibiotics active against pathogens in non-severe community acquired pneumonia: meta-analysis. BMJ, 2005, 330(7489): 456.
18. Eccles S, Pincus C, Higgins B, et al. Diagnosis and management of community and hospital acquired pneumonia in adults: summary of NICE guidance. BMJ, 2014, 349: 6722.

Chinese Journal of Evidence-Based Medicine

Drug usage and costs of pneumonia inpatients in Karamay Central Hospital in 2014

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