• 1. Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, 610041, P.R.China;
  • 2. West China School of Medicine, Sichuan University, Chengdu, 610041, P.R.China;
  • 3. Laboratory of Anesthesia and Critical Care, Emergency Medicine, Translational Neuroscience Centre, West China Hospital, Sichuan University, Chengdu, 610041, P.R.China;
ZHANG Wensheng, Email: zhangws@vip.163.com
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Objective  To overview the systematic reviews/meta-analyses of efficacy of FNB used as a postoperative analgesic technique among patients undergoing TKR. Methods  We electronically searched databases including The Cochrane Library, PubMed, EMbase, CNKI, WanFang Data and VIP from inception to July, 2016. Two reviewers independently screened literature and extracted data. AMSTAR tool was used to assess the methodological quality of included studies. The primary outcome was pain scores and the consumption of opoid medicine to evaluate the effectiveness of FNB. Results  A total of 16 systematic reviews/meta-analyses were included, involving the FNBvs. LIA, PMDI, EA, PCA and ACB, respectively. The results of quality assessment indicated medium scores with 3 to 9 scores. The overviews’ results showed that: at rest, FNB was not superior to LIA at 6h after TKR; it was superior to PMDI at 12h after TKR; it was also superior to PCA and LIA, but not superior to ACB at 24h after TKR. On movement, FNB was superior to PCA and LIA at 24h after TKR; it was also superior to PCA at 48h after TKR. As to the consumption of opoid medicine, the consumption in FNB group was more than LIA group at 12h after TKR. In addition, the consumption in FNB group was less than PCA and LIA at 24h after TKR, and it was also less than PCA and ACB at 48h. The satisfaction of patients who received FNB was better than ACB, EA and PCA. Conclusion  The current overview shows that FNB is more effective than PCA and LIA, the patients’ satisfaction is better. Due to the limitations of the quantity and quality of included studies, the above conclusions are needed to be verified by more studies.

Citation: CHENG Xu, ZHENG Linli, XU Yi, WU Jiahui, ZHANG Wensheng. The efficacy of femoral nerve block for postoperative analgesia of total knee replacement: an overview of the systematic reviews. Chinese Journal of Evidence-Based Medicine, 2017, 17(3): 283-290. doi: 10.7507/1672-2531.201701071 Copy

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