• 1. Department of General Surgery, Huaihe Hospital of Henan University; Center for Evidence-Based Medicine, Huaihe Hospital of Henan University, Kaifeng, 475000, P.R.China;
  • 2. Center for Evidence-Based Medicine, Henan University, Kaifeng 475000, P.R.China;
  • 3. Center for Evidence-Based and Translational Medicine, Zhongnan Hospital of Wuhan University; Center for Evidence-Based and Translational Medicine, Wuhan University; Department of Evidence-Based Medicine and Clinical Epidemiology, The Second Clinical College, Wuhan University, Wuhan, 430071, P.R.China;
  • 4. School of Nursing, Tianjin University of Traditional Chinese Medicine; Evidence-Based Nursing Center, Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, P.R.China;
REN Xuequn, Email: renxuequn001@163.com; ZENG Xiantao, Email: zengxiantao1128@163.com
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To perform a meta-analysis of single nucleotide polymorphism needs to calculate gene frequency. This paper employs allele model as an example to introduce how to calculate gene frequency and display the process of a meta-analysis of single nucleotide polymorphism data using Review Manager 5.3 software.

Citation: WANG Chaoyang, WENG Hong, JIN Yinghui, LI Binghui, REN Xuequn, ZENG Xiantao. How to perform meta-analysis of single nucleotide polymorphism data by Review Manager 5.3 software. Chinese Journal of Evidence-Based Medicine, 2018, 18(2): 244-248. doi: 10.7507/1672-2531.201707072 Copy

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