To perform a meta-analysis of single nucleotide polymorphism needs to calculate gene frequency. This paper employs allele model as an example to introduce how to calculate gene frequency and display the process of a meta-analysis of single nucleotide polymorphism data using Review Manager 5.3 software.
Citation: WANG Chaoyang, WENG Hong, JIN Yinghui, LI Binghui, REN Xuequn, ZENG Xiantao. How to perform meta-analysis of single nucleotide polymorphism data by Review Manager 5.3 software. Chinese Journal of Evidence-Based Medicine, 2018, 18(2): 244-248. doi: 10.7507/1672-2531.201707072 Copy