Relevant factors of early puberty timing: a systematic review_Chinese Journal of Evidence-Based Medicine

Authors：

YANG Bo ,  LIU Qin , LIU Shudan , DENG Xu , LI Wenyan , CHEN Yiwen , HUANG Xin , LUO Yan , WEN Yi

Department of Public Health and Management, Chongqing Medical University, Chongqing, 400016, P.R.China;

Corresponding author：

LIU Qin, Email: liuqin81622@163.com

Keywords：

Early puberty timing; Influencing factors; Systematic review

DOI：

10.7507/1672-2531.201708063

Video：

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ObjectivesTo systematically review the status quo of studies on the influencing factors of early puberty timing.MethodsWe searched VIP, CNKI, CBM, WanFang Data, PubMed, Ovid, Web of Science, EBSCO and The Cochrane Library to collect studies on the influencing factors of early puberty timing published up to November 16^th, 2016. Two reviewers independently screened literature, extracted data and assessed the risk of bias of included studies. Then, quantitative analysis and qualitative synthesis methods were used to analyze the studies.ResultsA total of 146 studies were included, among which 74 were case-control studies. The results showed that: the influencing factors on early puberty timing mainly included 10 aspects: obesity, dietary preference and nutritional intake, environmental endocrine disruptors, genetic, social psychologycal stress, social economic status, lifestyle, intrauterine fetal growth, maternal age at menarche and weight, adverse factors during pregnancy.ConclusionsThe current systematic review showed that obesity, genetic, environmental endocrine disruptors, intrauterine fetal growth and early maternal age at menarche may increase the risk of early puberty timing, while other factors remain controversial. While the definition of early puberty timing and related factors have not been unified, most studies focus on females and qualitative data with lack of in-depth analysis. Therefore high quality cohort studies and studies on males are required.

Citation： YANG Bo, LIU Qin, LIU Shudan, DENG Xu, LI Wenyan, CHEN Yiwen, HUANG Xin, LUO Yan, WEN Yi. Relevant factors of early puberty timing: a systematic review. Chinese Journal of Evidence-Based Medicine, 2018, 18(12): 1337-1351. doi: 10.7507/1672-2531.201708063 Copy

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Chinese Journal of Evidence-Based Medicine

Relevant factors of early puberty timing: a systematic review

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