The application value of 6-minute walking test in clinical evaluation of chronic heart failure_Chinese Journal of Evidence-Based Medicine

Authors：

HOU Yazhu ^1,2 ^# , YAN Lingyan ³ ^# ,  MAO Jingyuan ^1,2 , WANG Xianliang ^1,2 , LI Ling ⁴ , ZHONG Chengliang ⁵ , LIU Hanwen ^1,2 , ZHAO Zhiqiang ^1,2

1. Department of Cardiology, the First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, P.R.China;
2. National Clinical Research Base of Traditional Chinese Medicine for Coronary Heart Disease, Tianjin, 300193, P.R.China;
3. Graduate School, Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, P.R.China;
4. The Chinese Cochrane Center, West China Hospital, Chengdu, 610041, P.R.China;
5. Medical Statistics Room, First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, P.R.China;

Corresponding author：

MAO Jingyuan, Email: jymao@126.com

Keywords：

6-minute walking test; 6-minute walking distance; Chronic heart failure; Consistency; Influencing factor; Randomized controlled trial

DOI：

10.7507/1672-2531.201804092

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ObjectivesTo analyze the application value of 6-minute walking test (6MWT) in the clinical evaluation of chronic heart failure (CHF).MethodsPubMed, EMbase, The Cochrane Library, CBM, VIP, WanFang Data and CNKI databases were searched online to collect randomized controlled trials (RCTs) of 6-minute walking distance (6MWD) as the CHF evaluation index. Two reviewers independently screened literature, extracted data, and then analyzed data by using SPSS 17.0 statistical software. The 6MWD with symptom, quality of life, exercise tolerance (ETT), left ventricular ejection fraction (LVEF), peak oxygen consumption (pVO₂) were analyzed by Kappa consistency test, and the possible influencing factors of 6MWD were analyzed by logistic regression.ResultsA total of 158 RCTs involving 17 853 patients were included. The results of statistical analysis showed that: 6MWD was consistent with the improvement of symptoms, quality of life, ETT, LVEF and pVO₂ (Kappa>0.4). Baseline 6MWD (OR=2.91, 95%CI 1.278 to 6.634,P=0.011) and NYHA Ⅲ-Ⅳ ratio (OR=2.59, 95%CI 1.091 to 6.138, P=0.031) were the independent influencing factors for 6MWD improvement separately.ConclusionsThe 6MWT is an objective and reliable indicator of CHF evaluation.

Citation： HOU Yazhu, YAN Lingyan, MAO Jingyuan, WANG Xianliang, LI Ling, ZHONG Chengliang, LIU Hanwen, ZHAO Zhiqiang. The application value of 6-minute walking test in clinical evaluation of chronic heart failure. Chinese Journal of Evidence-Based Medicine, 2018, 18(9): 907-917. doi: 10.7507/1672-2531.201804092 Copy

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Chinese Journal of Evidence-Based Medicine

The application value of 6-minute walking test in clinical evaluation of chronic heart failure

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