An analysis of disease burden of colorectal cancer in China from 1990 to 2019_Chinese Journal of Evidence-Based Medicine

Authors：

WANG Na ^1,2 , LIU Jie ^2,3 , LI Xiaodong ² , WANG Chaoyang ^2,4 , ZI Hao ^2,5 , YANG Mengzhu ¹ , LEI Mengyuan ¹ , ZHANG Ying ¹ ,  LI Li ¹ ,  REN Xuequn ^2,4

1. School of Nursing and Health, Henan University, Kaifeng 475004, P.R.China;
2. Institutes of Evidence-Based Medicine and Knowledge Translation, Henan University, Kaifeng 475000, P.R.China;
3. Department of Nursing, Huaihe Hospital of Henan University, Kaifeng 475000, P.R.China;
4. Department of General Surgery, Huaihe Hospital of Henan University, Kaifeng 475000, P.R.China;
5. Center for Evidence-Based and Translational Medicine, Zhongnan Hospital of Wuhan University, Wuhan 430071, P.R.China;

Corresponding author：

LI Li, Email: lilihenu@163.com; REN Xuequn, Email: renxuequn001@163.com

Keywords：

Colorectal cancer; Incidence; Mortality; Annual average percentage change; Burden of disease; Disability-adjusted life year

DOI：

10.7507/1672-2531.202012006

Video：

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Objective To analyze the trend of disease burden of colorectal cancer (CRC) in China from 1990 to 2019.Methods Data was obtained from Global Burden of Disease Study 2019 (GBD 2019). Incidence, mortality, disability-adjusted life year (DALY), years of life lost (YLL), years lived with disability (YLD), and their corresponding standardized rate and annual average percentage change (AAPC) were used to describe the changes of disease burden of colorectal cancer in Chinese population between 1990 and 2019.Results Compared with 1990, the number of new cases, standardized incidence, the number of deaths and standardized mortality of CRC in China in 2019 increased by 474.03%, 144.01%, 230.14%, and 36.15%, respectively. The standardized mortality and standardized incidence of CRC in China had reached and gradually exceeded the global level since 2010. From 1990 to 2019, the overall standard incidence (AAPC=3.6%, P<0.05), standard mortality rate (AAPC=1.4%, P<0.05), and the standard DALY rate (AAPC=1.2%, P<0.05) of CRC in China showed an increasing trend. The incidence, mortality and DALY rates of males were higher than those of females, and gradually increased with age. Compared with 1990, the DALY, YLL, and YLD of CRC in 2019 increased by 134.3%, 127.69%, and 445.00%, and their corresponding standardized rates increased by 30.53%, 27.03%, and 187.29%, respectively, showing an overall upward trend.Conclusions From 1990 to 2019, the standardized incidence rate and standardized mortality rate of colorectal cancer in China have had a continuously increasing trend, and males and the elderly are high-risk groups. To reduce the burden of colorectal cancer in China, effective measures should be taken for prevention and management.

Citation： WANG Na, LIU Jie, LI Xiaodong, WANG Chaoyang, ZI Hao, YANG Mengzhu, LEI Mengyuan, ZHANG Ying, LI Li, REN Xuequn. An analysis of disease burden of colorectal cancer in China from 1990 to 2019. Chinese Journal of Evidence-Based Medicine, 2021, 21(5): 520-524. doi: 10.7507/1672-2531.202012006 Copy

1.	Bray F, Ferlay J, Soerjomataram I, et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin, 2018, 68(6): 394-424.
2.	Chen W, Zheng R, Baade PD, et al. Cancer statistics in China, 2015. CA Cancer J Clin, 2016, 66(2): 115-132.
3.	Arnold M, Sierra MS, Laversanne M, et al. Global patterns and trends in colorectal cancer incidence and mortality. Gut, 2017, 66(4): 683-691.
4.	Zhang L, Cao F, Zhang G, et al. Trends in and predictions of colorectal cancer incidence and mortality in China from 1990 to 2025. Front Oncol, 2019, 9: 98.
5.	Chen W, Zheng R, Zhang S, et al. Cancer incidence and mortality in China, 2013. Cancer Lett, 2017, 401: 63-71.
6.	Yang G, Wang Y, Zeng Y, et al. Rapid health transition in China, 1990-2010: findings from the Global Burden of Disease Study 2010. Lancet, 2013, 381(9882): 1987-2015.
7.	Zheng R, Zeng H, Zhang S, et al. National estimates of cancer prevalence in China, 2011. Cancer Lett, 2016, 370(1): 33-38.
8.	GBD 2019 Risk Factors Collaborators. Global burden of 87 risk factors in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet, 2020, 396(10258): 1223-1249.
9.	GBD 2019 Diseases and Injuries Collaborators. Global burden of 369 diseases and injuries in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet, 2020, 396(10258): 1204-1222.
10.	GBD 2019 Demographics Collaborators. Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950-2019: a comprehensive demographic analysis for the Global Burden of Disease Study 2019. Lancet, 2020, 396(10258): 1160-1203.
11.	Naghavi M, Makela S, Foreman K, et al. Algorithms for enhancing public health utility of national causes-of-death data. Popul Health Metr, 2010, 8: 9.
12.	Yu W, Jiang J, Xie L, et al. Mortality trends in colorectal cancer in China during 2000-2015: a joinpoint regression and age-period-cohort analysis. Prev Chronic Dis, 2018, 15: E156.
13.	郑荣寿, 孙可欣, 张思维, 等. 2015 年中国恶性肿瘤流行情况分析. 中华肿瘤杂志, 2019, 41(1): 19-28.
14.	Sung JJ, Lau JY, Goh KL, et al. Increasing incidence of colorectal cancer in Asia: implications for screening. Lancet Oncol, 2005, 6(11): 871-876.
15.	Zheng ZX, Zheng RS, Zhang SW, et al. Colorectal cancer incidence and mortality in China, 2010. Asian Pac J Cancer Prev, 2014, 15(19): 8455-8460.
16.	World Cancer Research Fund International/American Institute for Cancer Research. Continuous update project report: diet, nutrition, physical activity, and colorectal cancer. Available from: https://www.wcrf.org/dietandcancer.
17.	Song M, Garrett WS, Chan AT. Nutrients, foods, and colorectal cancer prevention. Gastroenterology, 2015, 148(6): 1244-1260.
18.	Chun YJ, Sohn SK, Song HK, et al. Associations of colorectal cancer incidence with nutrient and food group intakes in korean adults: a case-control study. Clin Nutr Res, 2015, 4(2): 110-123.
19.	Nguyen LH, Liu PH, Zheng X, et al. Sedentary behaviors, TV viewing time, and risk of young-onset colorectal cancer. JNCI Cancer Spectr, 2018, 2(4): y73.
20.	訾豪, 王江宜, 胡海亮, 等. 1990~2017 年中国膀胱癌疾病负担分析. 医学新知, 2020, 30(5): 328-335.
21.	邓通, 蔡林, 陈征, 等. 1990 年与 2017 年中国前列腺癌疾病负担分析. 医学新知, 2020, 30(4): 252-259.
22.	International Agency for Research on Cancer. Colorectal cancer. Available from: https://gco.iarc.fr/today/data/factsheets/cancers/10_8_9-Colorectum-fact-sheet.pdf.
23.	Keum N, Giovannucci E. Global burden of colorectal cancer: emerging trends, risk factors and prevention strategies. Nat Rev Gastroenterol Hepatol, 2019, 16(12): 713-732.
24.	Graff RE, Möller S, Passarelli MN, et al. Familial risk and heritability of colorectal cancer in the Nordic Twin Study of Cancer. Clin Gastroenterol Hepatol, 2017, 15(8): 1256-1264.
25.	Mousavi SM, Fallah M, Sundquist K, et al. Age- and time-dependent changes in cancer incidence among immigrants to Sweden: colorectal, lung, breast and prostate cancers. Int J Cancer, 2012, 131(2): E122-E128.
26.	Wilsnack RW, Wilsnack SC, Kristjanson AF, et al. Gender and alcohol consumption: patterns from the multinational GENACIS project. Addiction, 2009, 104(9): 1487-1500.
27.	World Health Organization. WHO global report on trends in prevalence of tobacco smoking 2015. Available from: http://apps.who.int/iris/bitstream/handle/10665/156262/9789241564922_eng.pdf;jsessionid=3E603A72D553D128773D0836AECE325E?sequence=1.
28.	Imamura F, Micha R, Khatibzadeh S, et al. Dietary quality among men and women in 187 countries in 1990 and 2010: a systematic assessment. Lancet Glob Health, 2015, 3(3): 132-142.
29.	Murphy N, Strickler HD, Stanczyk FZ, et al. A prospective evaluation of endogenous sex hormone levels and colorectal cancer risk in postmenopausal women. J Natl Cancer Inst, 2015, 107(10): djv210.

1. Bray F, Ferlay J, Soerjomataram I, et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin, 2018, 68(6): 394-424.
2. Chen W, Zheng R, Baade PD, et al. Cancer statistics in China, 2015. CA Cancer J Clin, 2016, 66(2): 115-132.
3. Arnold M, Sierra MS, Laversanne M, et al. Global patterns and trends in colorectal cancer incidence and mortality. Gut, 2017, 66(4): 683-691.
4. Zhang L, Cao F, Zhang G, et al. Trends in and predictions of colorectal cancer incidence and mortality in China from 1990 to 2025. Front Oncol, 2019, 9: 98.
5. Chen W, Zheng R, Zhang S, et al. Cancer incidence and mortality in China, 2013. Cancer Lett, 2017, 401: 63-71.
6. Yang G, Wang Y, Zeng Y, et al. Rapid health transition in China, 1990-2010: findings from the Global Burden of Disease Study 2010. Lancet, 2013, 381(9882): 1987-2015.
7. Zheng R, Zeng H, Zhang S, et al. National estimates of cancer prevalence in China, 2011. Cancer Lett, 2016, 370(1): 33-38.
8. GBD 2019 Risk Factors Collaborators. Global burden of 87 risk factors in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet, 2020, 396(10258): 1223-1249.
9. GBD 2019 Diseases and Injuries Collaborators. Global burden of 369 diseases and injuries in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet, 2020, 396(10258): 1204-1222.
10. GBD 2019 Demographics Collaborators. Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950-2019: a comprehensive demographic analysis for the Global Burden of Disease Study 2019. Lancet, 2020, 396(10258): 1160-1203.
11. Naghavi M, Makela S, Foreman K, et al. Algorithms for enhancing public health utility of national causes-of-death data. Popul Health Metr, 2010, 8: 9.
12. Yu W, Jiang J, Xie L, et al. Mortality trends in colorectal cancer in China during 2000-2015: a joinpoint regression and age-period-cohort analysis. Prev Chronic Dis, 2018, 15: E156.
13. 郑荣寿, 孙可欣, 张思维, 等. 2015 年中国恶性肿瘤流行情况分析. 中华肿瘤杂志, 2019, 41(1): 19-28.
14. Sung JJ, Lau JY, Goh KL, et al. Increasing incidence of colorectal cancer in Asia: implications for screening. Lancet Oncol, 2005, 6(11): 871-876.
15. Zheng ZX, Zheng RS, Zhang SW, et al. Colorectal cancer incidence and mortality in China, 2010. Asian Pac J Cancer Prev, 2014, 15(19): 8455-8460.
16. World Cancer Research Fund International/American Institute for Cancer Research. Continuous update project report: diet, nutrition, physical activity, and colorectal cancer. Available from: https://www.wcrf.org/dietandcancer.
17. Song M, Garrett WS, Chan AT. Nutrients, foods, and colorectal cancer prevention. Gastroenterology, 2015, 148(6): 1244-1260.
18. Chun YJ, Sohn SK, Song HK, et al. Associations of colorectal cancer incidence with nutrient and food group intakes in korean adults: a case-control study. Clin Nutr Res, 2015, 4(2): 110-123.
19. Nguyen LH, Liu PH, Zheng X, et al. Sedentary behaviors, TV viewing time, and risk of young-onset colorectal cancer. JNCI Cancer Spectr, 2018, 2(4): y73.
20. 訾豪, 王江宜, 胡海亮, 等. 1990~2017 年中国膀胱癌疾病负担分析. 医学新知, 2020, 30(5): 328-335.
21. 邓通, 蔡林, 陈征, 等. 1990 年与 2017 年中国前列腺癌疾病负担分析. 医学新知, 2020, 30(4): 252-259.
22. International Agency for Research on Cancer. Colorectal cancer. Available from: https://gco.iarc.fr/today/data/factsheets/cancers/10_8_9-Colorectum-fact-sheet.pdf.
23. Keum N, Giovannucci E. Global burden of colorectal cancer: emerging trends, risk factors and prevention strategies. Nat Rev Gastroenterol Hepatol, 2019, 16(12): 713-732.
24. Graff RE, Möller S, Passarelli MN, et al. Familial risk and heritability of colorectal cancer in the Nordic Twin Study of Cancer. Clin Gastroenterol Hepatol, 2017, 15(8): 1256-1264.
25. Mousavi SM, Fallah M, Sundquist K, et al. Age- and time-dependent changes in cancer incidence among immigrants to Sweden: colorectal, lung, breast and prostate cancers. Int J Cancer, 2012, 131(2): E122-E128.
26. Wilsnack RW, Wilsnack SC, Kristjanson AF, et al. Gender and alcohol consumption: patterns from the multinational GENACIS project. Addiction, 2009, 104(9): 1487-1500.
27. World Health Organization. WHO global report on trends in prevalence of tobacco smoking 2015. Available from: http://apps.who.int/iris/bitstream/handle/10665/156262/9789241564922_eng.pdf;jsessionid=3E603A72D553D128773D0836AECE325E?sequence=1.
28. Imamura F, Micha R, Khatibzadeh S, et al. Dietary quality among men and women in 187 countries in 1990 and 2010: a systematic assessment. Lancet Glob Health, 2015, 3(3): 132-142.
29. Murphy N, Strickler HD, Stanczyk FZ, et al. A prospective evaluation of endogenous sex hormone levels and colorectal cancer risk in postmenopausal women. J Natl Cancer Inst, 2015, 107(10): djv210.

Chinese Journal of Evidence-Based Medicine

An analysis of disease burden of colorectal cancer in China from 1990 to 2019

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