LU Cuncun 1,2,3 , KE Lixin 4 , TANG Hao 5 , LI Rui 1,2 , LI Jieyun 1,2 , YANG Kehu 1,2,6
  • 1. Evidence-Based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou 730000, P.R.China;
  • 2. Key Laboratory of Evidence-Based Medicine and Knowledge Translation of Gansu Province, Lanzhou 730000, P.R.China;
  • 3. Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, P.R.China;
  • 4. Hepatobiliary and Pancreatic Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, P.R.China;
  • 5. Department of Orthopedics, Zhuozhou City Hospital, Baoding 072750, P.R.China;
  • 6. Evidence-Based Social Science Center, School of Public Health, Lanzhou University, Lanzhou 730000, P.R.China;
LU Cuncun, Email: cuncunlu2017@163.com
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Objective To analyze the reporting and methodological quality of tranexamic acid meta-analyses published in Chinese journals. Methods The CNKI, WanFang Data, and CBM databases were electronically searched for meta-analyses of tranexamic acid from inception to August 12th, 2021. Two reviewers independently screened literature, extracted data, and used AMSTAR 2 and PRISMA 2009 to assess the methodological and reporting quality of publications. Results A total of 68 meta-analyses were included. The identified meta-analyses required improvement for items 2, 3, 4, 7, 8, 10, 12, 15, and 16 in the AMSTAR 2, and items 2, 5, 8, 12, 15, 17, 22, 24, and 27 in the PRISMA 2009 assessments, respectively. The methodological and reporting quality scores were positively correlated (rs=0.36, P=0.002). Linear regression analysis identified the mentioning of PRISMA and funding support as the independent factors potentially affecting the reporting quality score (P<0.05). Conclusions Both the methodological and reporting quality of the tranexamic acid meta-analyses published in Chinese journals require improvement.

Citation: LU Cuncun, KE Lixin, TANG Hao, LI Rui, LI Jieyun, YANG Kehu. Reporting and methodological quality of tranexamic acid meta-analyses published in Chinese journals. Chinese Journal of Evidence-Based Medicine, 2021, 21(11): 1332-1338. doi: 10.7507/1672-2531.202108167 Copy

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