Incidence trends of tuberculosis among Chinese students: a systematic review_Chinese Journal of Evidence-Based Medicine

Authors：

 LIU Yi ¹ , HUANG Xu ² , YIN Wenqin ¹ , SHI Gensheng ¹ , WANG Xiaoqing ³ , CHEN Song ⁴

1. School of Health and Rehabilitation, Jiangsu Nursing College, Huai’an 223300, P.R.China;
2. Department of Clinical Laboratory, Children’s Hospital of Nanjing Medical University, Nanjing 210008, P.R.China;
3. Department of Endocrinology, Huai’an Second People’s Hospital, Huai’an 223002, P.R.China;
4. Institute of Medicinal Biotechnology, Jiangsu College of Nursing, Huai’an 223000, P.R.China;

Corresponding author：

LIU Yi, Email: jsxzzghgz@163.com

Keywords：

Tuberculosis; Chinese student; Incidence rate; Meta-analysis; Systematic review; Cross-sectional study

DOI：

10.7507/1672-2531.202109054

Video：

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Abstract Full text Figures/Tables Video References Cited by

Objective To systematically review the trend of tuberculosis among Chinese students. Methods PubMed, Web of Science, EMbase, CBM, WanFang Data and CNKI databases were electronically searched to collect cross-sectional studies on the incidence and trend of tuberculosis among students in China from inception to August 2021. Two reviewers independently screened literature, extracted data and assessed the risk of bias of included studies; then, meta-analysis was performed by using Stata 15.0 software. Results A total of 97 cross-sectional studies were included. The results of meta-analysis showed that: the overall incidence of tuberculosis among students in China was 18.63 per 100 000 persons. The incidence in the northwest, south, northeast, north, east, central, and southwest 46.81, 11.22, 24.38, 12.77, 12.03, 18.95, and 39.26 per 100 000 persons, respectively. The incidence among university students, senior high school students, junior school students, and primary school students 38.17, 33.84, 8.85, and 1.68 per 100 000 persons, respectively. Conclusion Current evidence shows that the incidence of tuberculosis among students in China is high. Among them, the incidence rate of tuberculosis in the central and western regions, universities and high school students is relatively high.

Citation： LIU Yi, HUANG Xu, YIN Wenqin, SHI Gensheng, WANG Xiaoqing, CHEN Song. Incidence trends of tuberculosis among Chinese students: a systematic review. Chinese Journal of Evidence-Based Medicine, 2022, 22(1): 46-50. doi: 10.7507/1672-2531.202109054 Copy

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14.	何铁牛, 徐旭卿, 李群. 浙江省卫生部结核病控制项目县与非项目县家庭疾病经济负担的比较分析. 中国防痨杂志, 2002, 24(5): 34-37.
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17.	Zielonka TM. Epidemiological situation of tuberculosis in the world based on a report of the World Health Organization 2013. Przegl Epidemiol, 2015, 69(4): 687-691.
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19.	Cao D, Zhang Z, Yang Z, et al. The association between tuberculin skin test result and active tuberculosis risk of college students in Beijing, China: a retrospective cohort study. BMC Infect Dis, 2019, 19(1): 619.
20.	Ma MJ, Yang Y, Wang HB, et al. Transmissibility of tuberculosis among school contacts: an outbreak investigation in a boarding middle school, China. Infect Genet Evol, 2015, 32: 148-155.
21.	赖铿, 雷宇, 杜雨华, 等. 2014-2018年广州市学生肺结核发病时空特征分析. 中国防痨杂志, 2020, 42(6): 590-596.
22.	Mekonnen A, Collins JM, Aseffa A, et al. Prevalence of pulmonary tuberculosis among students in three eastern Ethiopian universities. Int J Tuberc Lung Dis, 2018, 22(10): 1210-1215.
23.	刘曦, 邢彦, 李婕, 等. 北京市海淀区高校结核病患者及其密切接触者筛查分析. 中华疾病控制杂志, 2017, 21(9): 900-903.
24.	Zhang S, Li X, Zhang T, et al. The experiences of high school students with pulmonary tuberculosis in China: a qualitative study. BMC Infect Dis, 2016, 16(1): 758.
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26.	Harling G, Lima Neto AS, Sousa GS, et al. Determinants of tuberculosis transmission and treatment abandonment in Fortaleza, Brazil. BMC Public Health, 2017, 17(1): 508.

1. Bloom BR. New promise for vaccines against tuberculosis. N Engl J Med, 2018, 379(17): 1672-1674.
2. Marks GB, Nguyen NV, Nguyen PTB, et al. Community-wide screening for tuberculosis in a high-prevalence setting. N Engl J Med, 2019, 381(14): 1347-1357.
3. WHO. Global tuberculosis report 2019. Available at: https://www.who.int/tb/publications/global_rep-ort/en/.
4. Tao NN, Li YF, Liu YX, et al. Epidemiological characteristics of pulmonary tuberculosis among children in Shandong, China, 2005-2017. BMC Infect Dis, 2019, 19(1): 408.
5. Pan D, Lin M, Lan R, et al. Tuberculosis transmission in households and classrooms of adolescent cases compared to the community in China. Int J Environ Res Public Health, 2018, 15(12): 2803.
6. Zhao F, Zhu JF, Tang WQ, et al. The epidemic trend and characteristics of tuberculosis for local population and migrants from 2010 to 2017 in Jiading, China. J Public Health, 2020, 28(3): 339-345.
7. Zhang S, Li X, Zhang T, et al. Framework for establishment of a comprehensive and standardized administration system for prevention and control of tuberculosis in college student community in China. Iran J Public Health, 2016, 45(10): 1300-1308.
8. Ou Y, Luo Z, Mou J, et al. Knowledge and determinants regarding tuberculosis among medical students in hunan, China: a cross-sectional study. BMC Public Health, 2018, 18(1): 730.
9. Sun Y, Zhang Y, Sundell J, et al. Dampness at dorm and its associations with allergy and airways infection among college students in China: a cross-sectional study. Indoor Air, 2009, 19(2): 174-182.
10. Yang G, Wang Y, Zeng Y, et al. Rapid health transition in China, 1990-2010: findings from the Global Burden of Disease Study 2010. Lancet, 2013, 381(9882): 1987-2015.
11. Togun T, Kampmann B, Stoker NG, et al. Anticipating the impact of the COVID-19 pandemic on TB patients and TB control programmes. Ann Clin Microbiol Antimicrob, 2020, 19(1): 21.
12. Guo Z, Xiao D, Wang X, et al. Epidemiological characteristics of pulmonary tuberculosis in mainland China from 2004 to 2015: a model-based analysis. BMC Public Health, 2019, 19(1): 219.
13. 鲍光喜, 李涛, 王欣. 费县计免疫工作管理及其接种质量分析. 现代预防医学, 2004, 31(5): 754.
14. 何铁牛, 徐旭卿, 李群. 浙江省卫生部结核病控制项目县与非项目县家庭疾病经济负担的比较分析. 中国防痨杂志, 2002, 24(5): 34-37.
15. You NN, Zhu LM, Li GL, et al. A tuberculosis school outbreak in China, 2018: reaching an often overlooked adolescent population. Epidemiol Infect, 2019, 147: e303.
16. Fang Y, Ma Y, Lu Q, et al. An outbreak of pulmonary tuberculosis and a follow-up investigation of latent tuberculosis in a high school in an eastern city in China, 2016-2019. PLoS One, 2021, 16(2): e0247564.
17. Zielonka TM. Epidemiological situation of tuberculosis in the world based on a report of the World Health Organization 2013. Przegl Epidemiol, 2015, 69(4): 687-691.
18. 杨月华. 某大学新生“肺结核防治知识健康教育处方”教育效果评. 现代预防医学, 2009, 36(10): 1909-1910.
19. Cao D, Zhang Z, Yang Z, et al. The association between tuberculin skin test result and active tuberculosis risk of college students in Beijing, China: a retrospective cohort study. BMC Infect Dis, 2019, 19(1): 619.
20. Ma MJ, Yang Y, Wang HB, et al. Transmissibility of tuberculosis among school contacts: an outbreak investigation in a boarding middle school, China. Infect Genet Evol, 2015, 32: 148-155.
21. 赖铿, 雷宇, 杜雨华, 等. 2014-2018年广州市学生肺结核发病时空特征分析. 中国防痨杂志, 2020, 42(6): 590-596.
22. Mekonnen A, Collins JM, Aseffa A, et al. Prevalence of pulmonary tuberculosis among students in three eastern Ethiopian universities. Int J Tuberc Lung Dis, 2018, 22(10): 1210-1215.
23. 刘曦, 邢彦, 李婕, 等. 北京市海淀区高校结核病患者及其密切接触者筛查分析. 中华疾病控制杂志, 2017, 21(9): 900-903.
24. Zhang S, Li X, Zhang T, et al. The experiences of high school students with pulmonary tuberculosis in China: a qualitative study. BMC Infect Dis, 2016, 16(1): 758.
25. Esposito S, Principi N, Leung CC, et al. Universal use of face masks for success against COVID-19: evidence and implications for prevention policies. Eur Respir J, 2020, 55(6): 2001260.
26. Harling G, Lima Neto AS, Sousa GS, et al. Determinants of tuberculosis transmission and treatment abandonment in Fortaleza, Brazil. BMC Public Health, 2017, 17(1): 508.

Chinese Journal of Evidence-Based Medicine

Incidence trends of tuberculosis among Chinese students: a systematic review

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