Quality evaluation of clinical guidelines and consensus for adult AIDS_Chinese Journal of Evidence-Based Medicine

Authors：

SHA Yinyin ¹ ,  XU Liran ² , MA Xiuxia ² , MENG Pengfei ^1,2 , SHAO Cancan ¹ , WANG Xueting ¹ , JIA Yandan ¹

1. Henan University of Chinese Medicine, Zhengzhou 450000, P. R. China;
2. The First Affiliated Hospital of Henan University of TCM, Zhengzhou 450008, P. R. China;

Corresponding author：

XU Liran, Email: xuliran666@sina.com

Keywords：

AIDS; Clinical guideline; Consensus; Quality assessment; AGREE Ⅱ; RIGHT

DOI：

10.7507/1672-2531.202202085

Video：

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Objective To evaluate the methodological and reporting quality of clinical guidelines and consensus for adult AIDS. Methods Databases including PubMed, EMbase, Web of Science, CBM, WanFang Data and CNKI were electronically searched and major guideline websites such as GIN, NICE, NGC and Yimaitong were also searched to collect guidelines and consensus for adult AIDS from inception to December 2021. Two researchers independently screened the literature and extracted data according to the inclusion and exclusion criteria. Four reviewers evaluated the methodological and reporting quality of the included guidelines and consensus by using AGREE Ⅱ and RIGHT, respectively. Results A total of 17 adult AIDS guidelines and consensus were included. The average scores of AGREE Ⅱ in various domains were 59.48% for scope and purpose, 37.17% for stakeholder involvement, 30.76% for rigor of development, 74.75% for clarity of presentation, 35.54% for applicability, and 50.49% for editorial independence. The items with the highest reporting rate among the RIGHT evaluation items were 1a, 1b and 1c (100.00%), followed by 3 and 4 (94.12%), 13a and 13b (88.24%), 7b and 11a (76.47%), and 5 (64.71%), and the remaining items were all reported below 60%. Results of subgroup analysis showed that the clarity of presentation, applicability and editorial independence of the guidelines for adult AIDS expressed in AGREE Ⅱ and the average score of RIGHT were higher than those of the consensuses for adult AIDS; the average scores of guidelines and consensuses based on evidence-based medicine in five domains of AGREE Ⅱ (scope and purpose, stakeholder involvement, rigor of development, clarity of presentation and applicability) and RIGHT were higher than those based on expert opinions or reviews. The foreign guidelines and consensus had higher average scores in the six domains of AGREE Ⅱ and the RIGHT score than the domestic guidelines. Conclusion The methodological quality and reporting quality of the published clinical guidelines and consensuses for adult AIDS is low; in particular, there is a certain gap between the national and international guidelines and consensuses. It is suggested that future guideline developers should refer to international standards, such as AGREE Ⅱ and RIGHT, formulate high-quality guidelines and promote their application to better regulate the diagnosis and treatment of adult AIDS.

Citation： SHA Yinyin, XU Liran, MA Xiuxia, MENG Pengfei, SHAO Cancan, WANG Xueting, JIA Yandan. Quality evaluation of clinical guidelines and consensus for adult AIDS. Chinese Journal of Evidence-Based Medicine, 2022, 22(6): 706-715. doi: 10.7507/1672-2531.202202085 Copy

1.	Joint United National Programme on HIV/AIDS. 2021-UNAIDS-data. Available at: https://www.unaids.org/en/resources/documents/2021/2021_unaids_data.
2.	Joint United National Programme on HIV/AIDS. Global AIDS strategy 2021-2026. Available at: https://www.unaids.org/en/Global-AIDS-Strategy-2021-2026.
3.	黄超, 杜亮, 陈耀龙, 等. 中国医务人员对临床实践指南的使用和需求调查. 中国循证医学杂志, 2019, 19(6): 635-638.
4.	Qaseem A, Forland F, Macbeth F, et al. Guidelines International Network: toward international standards for clinical practice guidelines. Ann Intern Med, 2012, 156(7): 525-531.
5.	AGREE Collaboration. Development and validation of an international appraisal instrument for assessing the quality of clinical practice guidelines: the AGREE project. Qual Saf Health Care, 2003, 12(1): 18-23.
6.	Brouwers MC, Kho ME, Browman GP, et al. AGREE II: advancing guideline development, reporting and evaluation in health care. CMAJ, 2010, 182(18): E839-842.
7.	Chen Y, Yang K, Marušic A, et al. A reporting tool for practice guidelines in health care: the RIGHT statement. Ann Intern Med, 2017, 166(2): 128-132.
8.	张雪芹, 邓宏勇. 循证医学数据库: 现状与趋势. 中国循证医学杂志, 2021, 21(6): 621-627.
9.	韦当, 王聪尧, 肖晓娟, 等. 指南研究与评价(AGREEⅡ)工具实例解读. 中国循证儿科杂志, 2013, 8(4): 316-319.
10.	Hoydonckx Y, Kumar P, Flamer D, et al. Quality of chronic pain interventional treatment guidelines from pain societies: assessment with the AGREE II instrument. Eur J Pain, 2020, 24(4): 704-721.
11.	Rachlis AR, Zarowny DP, Canadian HIV Trials Network Antiretroviral Working Group. Guidelines for antiretroviral therapy for HIV infection. CMAJ. 1998. 158(4): 496-505.
12.	Antinori A, Ammassari A, Torti C, et al. Italian consensus statement on management of HIV-infected individuals with advanced disease naïve to antiretroviral therapy. Infection, 2009, 37(3): 270-282.
13.	郑毓芳, 康来仪, 潘孝彰, 等. 人类免疫缺陷病毒感染特殊人群抗病毒治疗方案共识. 内科理论与实践, 2013, 8(2): 137-146.
14.	中华医学会热带病与寄生虫学分会艾滋病学组. 人类免疫缺陷病毒/艾滋病抗病毒治疗换药策略专家共识. 中华传染病杂志, 2019, (7): 397-402.
15.	中华中医药学会防治艾滋病分会. 艾滋病并发周围神经病变中西医协同治疗专家共识. 中医学报, 2020, 35(6): 1212-1214.
16.	王辉, 李在村, 赵红心, 等. 人类免疫缺陷病毒(HIV)抗病毒治疗二联简化疗法专家共识. 中国艾滋病性病, 2020, 26(3): 331-334, 336.
17.	中国性病艾滋病防治协会学术委员会外科学组, 中华医学会热带病与寄生虫学分会外科学组. 中国人类免疫缺陷病毒感染者围手术期抗病毒治疗专家共识. 中华实验和临床感染病杂志(电子版), 2019, 13(1): 1-5.
18.	Centers for Disease Control and Prevention. Report of the NIH panel to define principles of therapy of HIV infection and guidelines for the use of antiretroviral agents in HIV-infected adults and adolescents. MMWR, 1998, 47(RR-5): 43-82.
19.	AIDS Society of India. API consensus guidelines for use of antiretroviral therapy in adults (API-ART guidelines). J Assoc Physicians India, 2006, 54: 57-74.
20.	中华中医药学会防治艾滋病分会. 艾滋病中医诊疗指南(2013版). 中医学报, 2014, 29(5): 617-620.
21.	中华医学会感染病学分会艾滋病丙型肝炎学组, 中国疾病预防控制中心. 中国艾滋病诊疗指南(2021年版). 中国艾滋病性病, 2021, 27(11): 1182-1201.
22.	Hoen B, Bonnet F, Delaugerre C, et al. French 2013 guidelines for antiretroviral therapy of HIV-1 infection in adults. J Int AIDS Soc, 2014, 17(1): 19034.
23.	European AIDS Clinical Society. European AIDS Clinical Society Guidelines version 11.0. Available at: https://eacs.sanfordguide.com/.
24.	Manosuthi W, Ongwandee S, Bhakeecheep S, et al. Guidelines for antiretroviral therapy in HIV-1 infected adults and adolescents 2014, Thailand. AIDS Res Ther, 2015, 12: 12.
25.	Grace JM, Semple SJ, Combrink S. Exercise therapy for human immunodeficiency virus/AIDS patients: guidelines for clinical exercise therapists. J Exerc Sci Fit, 2015, 13(1): 49-56.
26.	Saag MS, Gandhi RT, Hoy JF, et al. Antiretroviral drugs for treatment and prevention of HIV infection in adults: 2020 recommendations of the International Antiviral Society-USA Panel. JAMA, 2020, 324(16): 1651-1669.
27.	World Health Organization. Consolidated guidelines on HIV prevention, testing, treatment, service delivery and monitoring: recommendations for a public health approach. Available at: https://apps.who.int/iris/handle/10665/342899?search-result=true&query=Consolidated+Guidelines+on+HIV+Prevention%2C+Testing%2C+Treatment%2C+Service&scope=&rpp=10&sort_by=score&order=desc.

1. Joint United National Programme on HIV/AIDS. 2021-UNAIDS-data. Available at: https://www.unaids.org/en/resources/documents/2021/2021_unaids_data.
2. Joint United National Programme on HIV/AIDS. Global AIDS strategy 2021-2026. Available at: https://www.unaids.org/en/Global-AIDS-Strategy-2021-2026.
3. 黄超, 杜亮, 陈耀龙, 等. 中国医务人员对临床实践指南的使用和需求调查. 中国循证医学杂志, 2019, 19(6): 635-638.
4. Qaseem A, Forland F, Macbeth F, et al. Guidelines International Network: toward international standards for clinical practice guidelines. Ann Intern Med, 2012, 156(7): 525-531.
5. AGREE Collaboration. Development and validation of an international appraisal instrument for assessing the quality of clinical practice guidelines: the AGREE project. Qual Saf Health Care, 2003, 12(1): 18-23.
6. Brouwers MC, Kho ME, Browman GP, et al. AGREE II: advancing guideline development, reporting and evaluation in health care. CMAJ, 2010, 182(18): E839-842.
7. Chen Y, Yang K, Marušic A, et al. A reporting tool for practice guidelines in health care: the RIGHT statement. Ann Intern Med, 2017, 166(2): 128-132.
8. 张雪芹, 邓宏勇. 循证医学数据库: 现状与趋势. 中国循证医学杂志, 2021, 21(6): 621-627.
9. 韦当, 王聪尧, 肖晓娟, 等. 指南研究与评价(AGREEⅡ)工具实例解读. 中国循证儿科杂志, 2013, 8(4): 316-319.
10. Hoydonckx Y, Kumar P, Flamer D, et al. Quality of chronic pain interventional treatment guidelines from pain societies: assessment with the AGREE II instrument. Eur J Pain, 2020, 24(4): 704-721.
11. Rachlis AR, Zarowny DP, Canadian HIV Trials Network Antiretroviral Working Group. Guidelines for antiretroviral therapy for HIV infection. CMAJ. 1998. 158(4): 496-505.
12. Antinori A, Ammassari A, Torti C, et al. Italian consensus statement on management of HIV-infected individuals with advanced disease naïve to antiretroviral therapy. Infection, 2009, 37(3): 270-282.
13. 郑毓芳, 康来仪, 潘孝彰, 等. 人类免疫缺陷病毒感染特殊人群抗病毒治疗方案共识. 内科理论与实践, 2013, 8(2): 137-146.
14. 中华医学会热带病与寄生虫学分会艾滋病学组. 人类免疫缺陷病毒/艾滋病抗病毒治疗换药策略专家共识. 中华传染病杂志, 2019, (7): 397-402.
15. 中华中医药学会防治艾滋病分会. 艾滋病并发周围神经病变中西医协同治疗专家共识. 中医学报, 2020, 35(6): 1212-1214.
16. 王辉, 李在村, 赵红心, 等. 人类免疫缺陷病毒(HIV)抗病毒治疗二联简化疗法专家共识. 中国艾滋病性病, 2020, 26(3): 331-334, 336.
17. 中国性病艾滋病防治协会学术委员会外科学组, 中华医学会热带病与寄生虫学分会外科学组. 中国人类免疫缺陷病毒感染者围手术期抗病毒治疗专家共识. 中华实验和临床感染病杂志(电子版), 2019, 13(1): 1-5.
18. Centers for Disease Control and Prevention. Report of the NIH panel to define principles of therapy of HIV infection and guidelines for the use of antiretroviral agents in HIV-infected adults and adolescents. MMWR, 1998, 47(RR-5): 43-82.
19. AIDS Society of India. API consensus guidelines for use of antiretroviral therapy in adults (API-ART guidelines). J Assoc Physicians India, 2006, 54: 57-74.
20. 中华中医药学会防治艾滋病分会. 艾滋病中医诊疗指南(2013版). 中医学报, 2014, 29(5): 617-620.
21. 中华医学会感染病学分会艾滋病丙型肝炎学组, 中国疾病预防控制中心. 中国艾滋病诊疗指南(2021年版). 中国艾滋病性病, 2021, 27(11): 1182-1201.
22. Hoen B, Bonnet F, Delaugerre C, et al. French 2013 guidelines for antiretroviral therapy of HIV-1 infection in adults. J Int AIDS Soc, 2014, 17(1): 19034.
23. European AIDS Clinical Society. European AIDS Clinical Society Guidelines version 11.0. Available at: https://eacs.sanfordguide.com/.
24. Manosuthi W, Ongwandee S, Bhakeecheep S, et al. Guidelines for antiretroviral therapy in HIV-1 infected adults and adolescents 2014, Thailand. AIDS Res Ther, 2015, 12: 12.
25. Grace JM, Semple SJ, Combrink S. Exercise therapy for human immunodeficiency virus/AIDS patients: guidelines for clinical exercise therapists. J Exerc Sci Fit, 2015, 13(1): 49-56.
26. Saag MS, Gandhi RT, Hoy JF, et al. Antiretroviral drugs for treatment and prevention of HIV infection in adults: 2020 recommendations of the International Antiviral Society-USA Panel. JAMA, 2020, 324(16): 1651-1669.
27. World Health Organization. Consolidated guidelines on HIV prevention, testing, treatment, service delivery and monitoring: recommendations for a public health approach. Available at: https://apps.who.int/iris/handle/10665/342899?search-result=true&query=Consolidated+Guidelines+on+HIV+Prevention%2C+Testing%2C+Treatment%2C+Service&scope=&rpp=10&sort_by=score&order=desc.

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