癫痫实用性临床定义_Journal of Epilepsy

Authors：

 王晓飞 ¹ , 吴逊 ²

1. ;
2. ;

Corresponding author：

王晓飞, Email: xf729@sina.com

Keywords：

癫痫; 发作; 定义; 非诱发性; 再发

DOI：

10.7507/2096-0247.20150011

Video：

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2005年的癫痫概念性定义:一种具有持久性产生癫痫样发作倾向的大脑疾患。实际上,这个定义通常用于间隔24 h以上的两次非诱发性痫性发作。国际抗癫痫联盟(ILAE)接受了一个特别工作组的建议,在没有满足两次非诱发性发作标准的特殊情况下,改变了实用性定义。特别工作组建议,在符合下列任何一项条件时,癫痫可以考虑为一种脑部疾病:①至少两次间隔>24 h的非诱发性(或反射性)痫性发作;②一次非诱发性(或反射性)痫性发作,在未来10年内,再次发作的可能性与两次非诱发性发作后的再发可能性相当(至少60%);③癫痫综合征的诊断,具有年龄相关的癫痫综合征的个人,目前已经超过该患病年龄,或保持无发作至少10年,并停用抗癫痫药物至少5年,这类癫痫被认为是可以解除的。"解除"与传统上"缓解"或"治愈"的观点不同。不同的实用性定义的形成服务于各种不同的目的。这次修订癫痫定义所使用的术语与常用的术语一致。

Citation： 王晓飞, 吴逊. 癫痫实用性临床定义. Journal of Epilepsy, 2015, 1(1): 73-79. doi: 10.7507/2096-0247.20150011 Copy

1.	Fisher RS, van Emde Boas W, Blume W, et al. Epileptic seizures and epilepsy:definitions proposed by the International League Against Epilepsy (ILAE) and the International Bureau for Epilepsy (IBE). Epilepsia, 2005, 46(4):470-472.
2.	Hauser WA, Annegers JF, Kurland LT. Prevalence of epilepsy in Rochester, Minnesota:1940-1980. Epilepsia, 1991, 32(4):429-445.
3.	Villanueva V, Sanchez-Alvarez JC, Pena P, et al. Treatment initiation in epilepsy:an expert consensus in Spain. Epilepsy Behav, 2010, 19(4):332-342.
4.	Berg AT, Shinnar S. The risk of seizure recurrence following a first unprovoked seizure:a quantitative review. Neurology, 1991, 41(7):965-972.
5.	Hauser WA, Rich SS, Lee JR, et al. Risk of recurrent seizures after two unprovoked seizures. N Engl J Med, 1998, 338(7):429-434.
6.	Hesdorffer DC, Benn EK, Cascino GD, et al. Is a first acute symptomatic seizure epilepsy? Mortality and risk for recurrent seizure. Epilepsia, 2009, 50(6):1102-1108.
7.	Beghi E, Carpio A, Forsgren L, et al. Recommendation for a definition of acute symptomatic seizure. Epilepsia, 2010, 51(5):671-675.
8.	Harding G. The reflex epilepsies with emphasis on photosensitive epilepsy. Suppl Clin Neurophysiol, 2004, 57(2):433-438.
9.	Wilden JA, Cohen-Gadol AA. Evaluation of first nonfebrile seizures. Am Fam Physician, 2012, 86(2):334-340.
10.	Stroink H, Brouwer OF, Arts WF, et al. The first unprovoked, untreated seizure in childhood:a hospital based study of the accuracy of the diagnosis, rate of recurrence, and long term outcome after recurrence. Dutch study of epilepsy in childhood. J Neurol Neurosurg Psychiatry, 1998, 64(5):595-600.
11.	Camfield P, Camfield C. Unprovoked status epilepticus:the prognosis for otherwise normal children with focal epilepsy. Pediatrics, 2012, 130(12):e501-506.
12.	Shinnar S, Berg AT, Moshe SL, et al. Risk of seizure recurrence following a first unprovoked seizure in childhood:a prospective study. Pediatrics, 1990, 85(3):1076-1085.
13.	Kim LG, Johnson TL, Marson AG, et al. Prediction of risk of seizure recurrence after a single seizure and early epilepsy:further results from the MESS trial. Lancet Neurol, 2006, 5(4):317-322.
14.	Hart YM, Sander JW, Johnson AL, et al. National General Practice Study of Epilepsy:recurrence after a first seizure. Lancet, 1990, 336(11):1271-1274.
15.	Berg AT, Berkovic SF, Brodie MJ, et al. (2010) Revised terminology and concepts for organization of seizures and epilepsies:Report of the ILAE Commission on Classification and Terminology, 2005-2009. Epilepsia, 2010, 51(3):676-685.
16.	Sinclair DB, Snyder TJ. Corticosteroids for the treatment of Landau-Kleffner syndrome and continuous spike-wave discharge during sleep. Pediatr Neurol, 2005, 32(8):300-306.
17.	Neligan A, Hauser WA, Sander JW. The epidemiology of the epilepsies. Handb Clin Neurol, 2012, 107(10):113-133.
18.	Rajna P, Solyom A. Oligoepilepsy:a real entity or the benign form of epileptic disorder? Ideggyogy Sz, 2011, 64(12):344-349.
19.	Geithner J, Schneider F, Wang Z, et al. Predictors for long-term seizure outcome in juvenile myoclonic epilepsy:25-63 years of follow-up. Epilepsia, 2012, 53(10):1379-1386.
20.	Rowland NC, Englot DJ, Cage TA, et al. A meta-analysis of predictors of seizure freedom in the surgical management of focal cortical dysplasia. J Neurosurg, 2012, 116(12):1035-1041.
21.	Kim W, Stramotas S, Choy W, et al. Prognostic factors for postoperative seizure outcomes after cavernous malformation treatment. J Clin Neurosci, 2011, 18(9):877-880.
22.	Berg AT, Testa FM, Levy SR. Complete remission in nonsyndromic childhood-onset epilepsy. Ann Neurol, 2011, 70(4):566-573.
23.	Goellner E, Bianchin MM, Burneo JG, et al. Timing of early and late seizure recurrence after temporal lobe epilepsy surgery. Epilepsia, 2013, 54(3):1933-1941.
24.	Buckingham SE, Chervoneva I, Sharan A, et al. Latency to first seizure after temporal lobectomy predicts long-term outcome. Epilepsia, 2010, 51(2):1987-1993.
25.	Lindsten H, Stenlund H, Forsgren L. Remission of seizures in a population-based adult cohort with a newly diagnosed unprovoked epileptic seizure. Epilepsia, 2001, 42(11):1025-1030.
26.	Lossius MI, Hessen E, Mowinckel P, et al. Consequences of antiepileptic drug withdrawal:a randomized, double-blind study (Akershus Study). Epilepsia, 2008, 49(10):455-463.
27.	Chadwick D, Taylor J, Johnson T. Outcomes after seizure recurrence in people with well-controlled epilepsy and the factors that influence it. The MRC Antiepileptic Drug Withdrawal Group. Epilepsia, 1996, 37(6):1043-1050.
28.	Monteiro L, Coelho T, Stocker A. Neurocysticercosis-a review of 231 cases. Infection, 1992, 20(2):61-65.
29.	Polman CH, Reingold SC, Banwell B, et al. Diagnostic criteria for multiple sclerosis:2010 revisions to the McDonald criteria. Ann Neurol, 2011, 69(11):292-302.
30.	Beghi E, Balzarini C, Bogliun G, et al. Reliability of the El Escorial diagnostic criteria for amyotrophic lateral sclerosis. Neuroepidemiology, 2002, 21(9):265-270.
31.	Silberstein S, Loder E, Diamond S, et al. Probable migraine in the United States:results of the American Migraine Prevalence and Prevention (AMPP) study. Cephalalgia, 2007, 27(10):220-229.
32.	Tang WK, Chan SS, Chiu HF, et al. Impact of applying NINDSAIREN criteria of probable vascular dementia to clinical and radiological characteristics of a stroke cohort with dementia. Cerebrovasc Dis, 2004, 18(10):98-103.

1. Fisher RS, van Emde Boas W, Blume W, et al. Epileptic seizures and epilepsy:definitions proposed by the International League Against Epilepsy (ILAE) and the International Bureau for Epilepsy (IBE). Epilepsia, 2005, 46(4):470-472.
2. Hauser WA, Annegers JF, Kurland LT. Prevalence of epilepsy in Rochester, Minnesota:1940-1980. Epilepsia, 1991, 32(4):429-445.
3. Villanueva V, Sanchez-Alvarez JC, Pena P, et al. Treatment initiation in epilepsy:an expert consensus in Spain. Epilepsy Behav, 2010, 19(4):332-342.
4. Berg AT, Shinnar S. The risk of seizure recurrence following a first unprovoked seizure:a quantitative review. Neurology, 1991, 41(7):965-972.
5. Hauser WA, Rich SS, Lee JR, et al. Risk of recurrent seizures after two unprovoked seizures. N Engl J Med, 1998, 338(7):429-434.
6. Hesdorffer DC, Benn EK, Cascino GD, et al. Is a first acute symptomatic seizure epilepsy? Mortality and risk for recurrent seizure. Epilepsia, 2009, 50(6):1102-1108.
7. Beghi E, Carpio A, Forsgren L, et al. Recommendation for a definition of acute symptomatic seizure. Epilepsia, 2010, 51(5):671-675.
8. Harding G. The reflex epilepsies with emphasis on photosensitive epilepsy. Suppl Clin Neurophysiol, 2004, 57(2):433-438.
9. Wilden JA, Cohen-Gadol AA. Evaluation of first nonfebrile seizures. Am Fam Physician, 2012, 86(2):334-340.
10. Stroink H, Brouwer OF, Arts WF, et al. The first unprovoked, untreated seizure in childhood:a hospital based study of the accuracy of the diagnosis, rate of recurrence, and long term outcome after recurrence. Dutch study of epilepsy in childhood. J Neurol Neurosurg Psychiatry, 1998, 64(5):595-600.
11. Camfield P, Camfield C. Unprovoked status epilepticus:the prognosis for otherwise normal children with focal epilepsy. Pediatrics, 2012, 130(12):e501-506.
12. Shinnar S, Berg AT, Moshe SL, et al. Risk of seizure recurrence following a first unprovoked seizure in childhood:a prospective study. Pediatrics, 1990, 85(3):1076-1085.
13. Kim LG, Johnson TL, Marson AG, et al. Prediction of risk of seizure recurrence after a single seizure and early epilepsy:further results from the MESS trial. Lancet Neurol, 2006, 5(4):317-322.
14. Hart YM, Sander JW, Johnson AL, et al. National General Practice Study of Epilepsy:recurrence after a first seizure. Lancet, 1990, 336(11):1271-1274.
15. Berg AT, Berkovic SF, Brodie MJ, et al. (2010) Revised terminology and concepts for organization of seizures and epilepsies:Report of the ILAE Commission on Classification and Terminology, 2005-2009. Epilepsia, 2010, 51(3):676-685.
16. Sinclair DB, Snyder TJ. Corticosteroids for the treatment of Landau-Kleffner syndrome and continuous spike-wave discharge during sleep. Pediatr Neurol, 2005, 32(8):300-306.
17. Neligan A, Hauser WA, Sander JW. The epidemiology of the epilepsies. Handb Clin Neurol, 2012, 107(10):113-133.
18. Rajna P, Solyom A. Oligoepilepsy:a real entity or the benign form of epileptic disorder? Ideggyogy Sz, 2011, 64(12):344-349.
19. Geithner J, Schneider F, Wang Z, et al. Predictors for long-term seizure outcome in juvenile myoclonic epilepsy:25-63 years of follow-up. Epilepsia, 2012, 53(10):1379-1386.
20. Rowland NC, Englot DJ, Cage TA, et al. A meta-analysis of predictors of seizure freedom in the surgical management of focal cortical dysplasia. J Neurosurg, 2012, 116(12):1035-1041.
21. Kim W, Stramotas S, Choy W, et al. Prognostic factors for postoperative seizure outcomes after cavernous malformation treatment. J Clin Neurosci, 2011, 18(9):877-880.
22. Berg AT, Testa FM, Levy SR. Complete remission in nonsyndromic childhood-onset epilepsy. Ann Neurol, 2011, 70(4):566-573.
23. Goellner E, Bianchin MM, Burneo JG, et al. Timing of early and late seizure recurrence after temporal lobe epilepsy surgery. Epilepsia, 2013, 54(3):1933-1941.
24. Buckingham SE, Chervoneva I, Sharan A, et al. Latency to first seizure after temporal lobectomy predicts long-term outcome. Epilepsia, 2010, 51(2):1987-1993.
25. Lindsten H, Stenlund H, Forsgren L. Remission of seizures in a population-based adult cohort with a newly diagnosed unprovoked epileptic seizure. Epilepsia, 2001, 42(11):1025-1030.
26. Lossius MI, Hessen E, Mowinckel P, et al. Consequences of antiepileptic drug withdrawal:a randomized, double-blind study (Akershus Study). Epilepsia, 2008, 49(10):455-463.
27. Chadwick D, Taylor J, Johnson T. Outcomes after seizure recurrence in people with well-controlled epilepsy and the factors that influence it. The MRC Antiepileptic Drug Withdrawal Group. Epilepsia, 1996, 37(6):1043-1050.
28. Monteiro L, Coelho T, Stocker A. Neurocysticercosis-a review of 231 cases. Infection, 1992, 20(2):61-65.
29. Polman CH, Reingold SC, Banwell B, et al. Diagnostic criteria for multiple sclerosis:2010 revisions to the McDonald criteria. Ann Neurol, 2011, 69(11):292-302.
30. Beghi E, Balzarini C, Bogliun G, et al. Reliability of the El Escorial diagnostic criteria for amyotrophic lateral sclerosis. Neuroepidemiology, 2002, 21(9):265-270.
31. Silberstein S, Loder E, Diamond S, et al. Probable migraine in the United States:results of the American Migraine Prevalence and Prevention (AMPP) study. Cephalalgia, 2007, 27(10):220-229.
32. Tang WK, Chan SS, Chiu HF, et al. Impact of applying NINDSAIREN criteria of probable vascular dementia to clinical and radiological characteristics of a stroke cohort with dementia. Cerebrovasc Dis, 2004, 18(10):98-103.

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