Objective To explore and clarify the relationship between epileptic seizure and inducing factors. Avoid inducing factors and reduce epileptic seizure, so as to improve the quality of life in patients with epilepsy.Methods Clinical data of 604 patients diagnosed with epilepsy in Xijing Hospital of Air Force Military Medical University from January 2018 to January 2019 were collected. The clinical data of patients with epilepsy were followed up 6 months.Results Among the 604 patients, 318 (52.6%) were seizure-free in the last 6 months, 286 (47.4%) had seizures. 169 (59.1%) had seizures with at least one inducing factor. Common inducing factors: 123 cases of sleep disorder (72.8%), 114 cases of emotion changes (67.5%), 87 cases of irregular medication (51.5%), 97 cases of diet related (57.4%), 33 cases of menstruation and pregnancy (19.5%), etc. Using the χ² test, seizures with age, gender differences had no statistical significance (P > 0.05), but seizure type was statistically different between inducing factors. In generalized seizures, tonic-clonic seizures associated with sleep deprivation (χ²= 0.189), absence seizures and anger (χ²= 0.237), pressure (χ²= 0.203), irregular life (χ²= 0.214). In the focal seizures, focal motor seizures was correlated with coffee consumption (χ²=0.145), focal sensory seizures with cold (χ²=0.235), electronic equipment use (χ² =0.153), satiety (χ² =0.257). Complex partial seizures was correlated with anger (χ² =0.229), stress (χ² =0.187), and cold (χ² =0.198). The secondarily generalized seizures was correlated with drug missing (χ² =0.231), sleep deprivation (χ² =0.158), stress (χ² =0.161), cold (χ² =0.263), satiety (χ² =0.182). Among the inducing factors, sleep deprivation was correlated with anger (χ² =0.167), fatigue (χ² =0.283), and stress (χ² =0.230).Conclusions Epileptic seizure were usually induced by a variety of factors. Generalized seizures were associated with sleep disorders, emotional changes, stress, irregular life, etc. While focal seizures were associated with stress, emotional changes, sleep disorders, cold, satiety, etc. An analysis of the triggers found that sleep deprivation was associated with anger, fatigue, and stress. Therefore, to clarify the inducing factors of epileptic seizure, avoid the inducing factors as much as possible, reduce the harm caused by seizures, and improve the quality of life of patients.

Citation： CAO Mi, DENG Yanchun. Preliminary investigation on inducing factors of epileptic seizures. Journal of Epilepsy, 2019, 5(4): 263-267. doi: 10.7507/2096-0247.20190044 Copy