米诺地尔治疗血液透析伴顽固性高血压一例_West China Medical Journal

Authors：

田茂露 , 刘晓霞 ,  胡章学

Corresponding author：

胡章学, Email: tianmaolu2005@163.com

Keywords：

米诺地尔; 顽固性高血压; 血液透析

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【摘要】　目的　探讨米诺地尔对血液透析伴顽固性高血压的降压价值。　方法　观察1例血液透析伴顽固性高血压患者米诺地尔的降压疗效，分析米诺地尔的临床应用及不良反应。　结果　米诺地尔能快速高效地控制患者的顽固性高血压状态，且小剂量长期维持治疗未发生明显药物相关副作用。　结论　米诺地尔降压效果显著、起效迅速，但鉴于使用米诺地尔的潜在毒副作用较多，该药应该被严格限制到对足量传统降压药无效或伴有不能接受的药物并发症患者。

Citation： 田茂露,刘晓霞,胡章学. 米诺地尔治疗血液透析伴顽固性高血压一例. West China Medical Journal, 2011, 26(12): 1870-1871. doi: Copy

1.	Mahony JF, Gibson GR, Sheil AG, et al. Bilateral nephrectomy for malignant hypertension[J]. Lancet, 1972, 299(7759): 1036-1038.
2.	Pettinger WA, Mitchell HC. Minoxidil--an alternative to nephrectomy for refractory hypertension[J]. N Engl J Med, 1973, 289(4): 167-171.
3.	Black RN, Hunter SJ, Atkinson AB. Usefulness of the vasodilator minoxidil in resistant hypertension[J]. J Hypertens, 2007, 25(5): 1102-1103.
4.	Halling SE, Asling-Monemi K, Herthelius M, et al. Minoxidil therapy in children and young adult patients with renal disease and refractory hypertension: value when multidrug regimens have failed to achieve blood pressure control[J]. J Hum Hypertens, 2010, 24(8): 552-554.
5.	Black RNA, Hunter SJ, Atkinson AB. Refractory hypertension can often be helped by the use of the potent vasodilator minoxidil: results in 13 patients, 12 of whom were already receiving angiotensin converting enzyme inhibitors or angiotensin II receptor antagonists[J]. Endocrine Abstracts, 2005, 9: 12.
6.	刘双信, 史伟, 梁馨苓, 等. 米诺地尔在治疗血液透析伴顽固性高血压中的应用[J]. 中国血液净化, 2004, 7(3): 355-357.
7.	Javier R, Dumler F, Park JH, et al. Long-term treatment with minoxidil in patients with severe renal failure[J]. J Cardiovasc Pharmacol, 1980, 2(Suppl 2): S149-S155.
8.	Luft FC, Bloch R, Szwed JJ, et al. Minoxidil treatment of malignant hypertension: Recovery of renal function[J]. JAMA, 1978, 240(18): 1985-1987.
9.	Gottlieb TB, Katz FH, Chidsey CA 3rd. Combined therapy with vasodilator drugs and beta-adrenergic blockade in hypertension: a comparative study of minoxidil and hydralazine[J]. Circulation, 1972, 45(3): 571-582.
10.	McChesney JA, Amend WJ Jr. Minoxidil in the treatment of refractory hypertension due to a spectrum of causes[J]. J Cardiovasc Pharmacol, 1980, 2(Suppl 2): 131-141.
11.	Mitchell HC, Pettinger WA. Long-term treatment of refractory hypertensive patients with minoxidil[J]. JAMA, 1978, 239(20): 2131-2138.
12.	Earhart RN, Ball J, Nuss DD, et al. Minoxidil-induced hypertrichosis: treatment with calcium thioglycolate depilatory[J]. South Med J, 1977, 70(4): 442-443.
13.	Gilmore E, Weil J, Chidsey C. Treatment of essential hypertension with a new vasodilator in combination with beta adrenergic blockade [J]. N Engl J Med, 1970, 282(10): 521-527.
14.	Zarate A, Gelfand MC, Horton JD, et al. Pericardial effusion associated with minoxidil therapy in dialyzed patients[J]. Int J Artif Organs, 1980, 3(1): 15-17.
15.	Hall D, Froer DH, Loracher C. Treatment of severe hypertension with minoxidil and its effects on systemic and pulmonary haemodynamics[J]. Clin Sci Mol Med Suppl, 1976, 3: 587-589.

1. 　Mahony JF, Gibson GR, Sheil AG, et al. Bilateral nephrectomy for malignant hypertension[J]. Lancet, 1972, 299(7759): 1036-1038.
2. 　Pettinger WA, Mitchell HC. Minoxidil--an alternative to nephrectomy for refractory hypertension[J]. N Engl J Med, 1973, 289(4): 167-171.
3. 　Black RN, Hunter SJ, Atkinson AB. Usefulness of the vasodilator minoxidil in resistant hypertension[J]. J Hypertens, 2007, 25(5): 1102-1103.
4. 　Halling SE, Asling-Monemi K, Herthelius M, et al. Minoxidil therapy in children and young adult patients with renal disease and refractory hypertension: value when multidrug regimens have failed to achieve blood pressure control[J]. J Hum Hypertens, 2010, 24(8): 552-554.
5. 　Black RNA, Hunter SJ, Atkinson AB. Refractory hypertension can often be helped by the use of the potent vasodilator minoxidil: results in 13 patients, 12 of whom were already receiving angiotensin converting enzyme inhibitors or angiotensin II receptor antagonists[J]. Endocrine Abstracts, 2005, 9: 12.
6. 　刘双信, 史伟, 梁馨苓, 等. 米诺地尔在治疗血液透析伴顽固性高血压中的应用[J]. 中国血液净化, 2004, 7(3): 355-357.
7. 　Javier R, Dumler F, Park JH, et al. Long-term treatment with minoxidil in patients with severe renal failure[J]. J Cardiovasc Pharmacol, 1980, 2(Suppl 2): S149-S155.
8. 　Luft FC, Bloch R, Szwed JJ, et al. Minoxidil treatment of malignant hypertension: Recovery of renal function[J]. JAMA, 1978, 240(18): 1985-1987.
9. 　Gottlieb TB, Katz FH, Chidsey CA 3rd. Combined therapy with vasodilator drugs and beta-adrenergic blockade in hypertension: a comparative study of minoxidil and hydralazine[J]. Circulation, 1972, 45(3): 571-582.
10. 　McChesney JA, Amend WJ Jr. Minoxidil in the treatment of refractory hypertension due to a spectrum of causes[J]. J Cardiovasc Pharmacol, 1980, 2(Suppl 2): 131-141.
11. 　Mitchell HC, Pettinger WA. Long-term treatment of refractory hypertensive patients with minoxidil[J]. JAMA, 1978, 239(20): 2131-2138.
12. 　Earhart RN, Ball J, Nuss DD, et al. Minoxidil-induced hypertrichosis: treatment with calcium thioglycolate depilatory[J]. South Med J, 1977, 70(4): 442-443.
13. 　Gilmore E, Weil J, Chidsey C. Treatment of essential hypertension with a new vasodilator in combination with beta adrenergic blockade [J]. N Engl J Med, 1970, 282(10): 521-527.
14. 　Zarate A, Gelfand MC, Horton JD, et al. Pericardial effusion associated with minoxidil therapy in dialyzed patients[J]. Int J Artif Organs, 1980, 3(1): 15-17.
15. 　Hall D, Froer DH, Loracher C. Treatment of severe hypertension with minoxidil and its effects on systemic and pulmonary haemodynamics[J]. Clin Sci Mol Med Suppl, 1976, 3: 587-589.

West China Medical Journal

米诺地尔治疗血液透析伴顽固性高血压一例

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