帕瑞昔布钠超前镇痛在妇科腹腔镜术中的应用_West China Medical Journal

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黄井林 , 钟定萍 , 付强

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Keywords：

帕瑞昔布钠; 超前镇痛; 妇科; 腹腔镜手术

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【摘要】　目的　探讨帕瑞昔布钠超前镇痛对妇科腹腔镜术患者的影响。　方法　 2009年9-10月随机选择行妇科腹腔镜术患者60例，分为试验组、对照组各30例。试验组手术前15 min静脉注射帕瑞昔布钠40 mg （10 mL），对照组注射生理盐水10 mL，记录术后1、2、4、6、12、24 h视觉模拟评分（VAS）。　结果　试验组VAS明显低于对照组，差异有统计学意义（P lt;0.05）。　结论　帕瑞昔布钠超前镇痛对妇科腹腔镜手术患者有较好的镇痛效果。

Citation： 黄井林,钟定萍,付强. 帕瑞昔布钠超前镇痛在妇科腹腔镜术中的应用. West China Medical Journal, 2010, 25(12): 2258-2259. doi: Copy

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2. 　Kissin T. Preemptive analgesia [J]. Anesthesiology, 2000, 93(4): 1138-1143.
3. 　王玉珍, 张小洺, 姚尚龙. 帕瑞昔布钠对超前镇痛腹腔镜胆囊切除术后疼痛的观察[J]. 临床麻醉学杂志, 2005, 21(9): 638-639.
4. 　Power I, Barratt S. Analgesic Agents for the Postoperative Period: Nonopioids[J]. Surg Clin North Am, 1999, 7(9): 275-295.
5. 　吴新民, 岳云, 张利萍. 术后镇痛中帕瑞昔布钠对吗啡用量的节俭作用和安全性[J]. 临床麻醉学杂志, 2007, 27(1): 7-10.
6. 　Rasmussen GL, Steckner K, Hogue C, et al. Intravenous parecoxib sodium foracute pain after orthopedic knee surgery[J]. Am J Orthop (Belle Mead NJ), 2002, 31(6): 336-343.
7. 　Malan TP Jr, Gordon S, Hubbard R, et al. The cyclooxygenase-2-specific inhibitor parecoxib sodium is as effective as 12 mg of morphine administered intramuscularly for treating pain after gynecologic laparotomy surgery[J]. Anesth Analg, 2005, 100(2): 454-460.
8. 　Gan TJ, Joshi GP, Zhao SZ, et al. Presurgical intravenous parecoxib sodium and follow-up oral valdecoxib for pain management after laparoscopic cholecystectomy surgery reduces opioid requirements and opioid-related adverse effects[J]. Acta Anaesthesiol Scand, 2004, 48(9): 1194-1207.

West China Medical Journal

帕瑞昔布钠超前镇痛在妇科腹腔镜术中的应用

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