【摘要】　目的　 对市场上流通使用的血塞通注射液在溶血性方面的状况进行考察与研究。　方法　 按《中国药典》2005年版一部附录ⅩⅧ B中药注射剂安全性检查法应用指导原则和中药、天然药物刺激性和溶血性研究的技术指导原则，对11 个厂家共计27 批血塞通注射液每批次样品制备4 个浓度，进行溶血实验研究，并采用分光光度法（545 λ/nm）测定计算溶血率，比较各批次样品的溶血率。　结果　 不同厂家甚至同一厂家不同批次的血塞通注射液溶血率存在一定差异。　结论　 在临床使用中应注意用量，过量使用可能导致溶血引起的不良反应；同时，应注意溶血引起的临床不良反应的观测。
【Abstract】　Objective　 To explore the hemolysis of Xuesaitong injection.　Methods　 According to the Guiding Principles of safety tests on traditional Chinese medicine injection in Annex ⅩⅧ B, Chinese Pharmacopoeia, 2005 Edition 1, and Technical Guidelines of studies on the irritability and hemolytic activity of traditional Chinese medicine and natural medicine, a total of 27 samples of Xuesaitong injections (each sample was diluted into four concentrations) produced by 11 manufacturers had been examined. Spectrophotometry (545 λ/nm) was used to calculate the hemolytic rate.　Results　 There was a certain difference in the hemolytic rate among several samples of Xuesaitong injections produced by different manufacturers, or even different batches by the same manufacturer.　Conclusion　 The dosage of Xuesaitong injections should be noted in clinical use. Excessive use may lead to adverse reactions caused by hemolysis; at the same time, clinical adverse reactions caused by hemolysis should be observed.

Citation： ZHAO Yi,YANG Chongyi,LIU Qin. Hemolysis of Xuesaitong Injection. West China Medical Journal, 2010, 25(12): 2225-2227. doi: Copy