Study of the Risk Factors in Obstructive Sleep ApneaHypopnea Syndrome_West China Medical Journal

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Department of OtolaryngologyHead & Neck Surgery，West China Hospital，Sichuan University，Chengdu 610041，China;

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Keywords：

呼吸暂停; 低通气; 肥胖

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目的:探讨阻塞性睡眠呼吸暂停低通气综合征（Obstructive Sleep ApneaHypopnea Syndrome，OSAHS）的危险因素。方法:192例就诊于睡眠实验室的患者进行标准化问卷填调查，测量颈围、腰围、臀围、身高和体重及整夜多导睡眠监测，分析性别、年龄和肥胖因素与OSAHS严重程度的关系。结果:OSAHS患者在症状、病情及人体测量学指标方面存在性别差异；发病年龄主要分布在31~60岁；OSAHS患者的体重指数（Body Mass Index，BMI）、颈围、腰臀比与AHI、氧减指数、最低血氧饱和度相关。结论:OSAHS的发生及严重程度与性别、年龄和肥胖等危险因素密切相关。

Citation： WANG Liman,ZHOU Guangyao,LI Chunhua,et al.. Study of the Risk Factors in Obstructive Sleep ApneaHypopnea Syndrome. West China Medical Journal, 2009, 24(1): 46-49. doi: Copy

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1. Duran J，Esnaola S，Rubio R，et al.Obstructive sleep apneahypopnea and related clinical features in a populationbased sample of subjects aged 30 to 70 yr[J].Am J Respir Crit Care Med，2001，163（3 Pt 1）:685-689..
2. 中华医学会耳鼻咽喉科学分会.阻塞性睡眠呼吸暂停低通气综合征诊断依据和疗效评定标准暨悬雍垂腭咽成形术适应证（杭州）[J].中华耳鼻咽喉科杂志，2002，37:403-404..
3. Redline S，Kump K，Tishler PV，et al.Gender differences in sleep disordered breathing in a communitybased sample[J].Am J Respir Crit Care Med，1994，149（3 Pt 1）:722-726。.
4. Popovic RM，White DP.Influence of gender on waking genioglossal electromyogram and upper airway resistance[J].Am J Respir Crit Care Med，1995，152（2）:725-731..
5. Popovic RM，White DP.Upper airway muscle activity in normal women:influence of hormonal status[J].J Appl Physiol，1998，84（3）:1055-1062..
6. Wetter DW，Young TB，Bidwell TR，et al.Smoking as a risk factor for sleep disordered breathing[J].Arch Intern Med，1994，154（19）:2219-2224..
7. AncoliIsrael S，Kripke DF，Mason W，et al.Sleep apnea and periodic movements in an aging sample[J].J Gerontol，1985，40（4）:419-425..
8. AncoliIsrael S，Kripke DF，Klauber MR，et al.Sleepdisordered breathing in communitydwelling elderly[J].Sleep，1991，14（6）:486-495..
9. Bixler EO，Vgontzas AN，Ten Have T，et al.Effects of age on sleep apnea in men:Ⅰ.Prevalence and severity[J].Am J Respir Crit Care Med，1998，157（1）:144-148..
10. Sforza E，Bacon W，Weiss T，et al.Upper airway collapsibility and cephalometric variables in patients with obstructive sleep apnea[J].Am J Respir Crit Care Med，2000，161（2 Pt 1）:347-352..
11. Vgontzas AN，Papanicolaou DA，Bixler EO，et al.Sleep apnea and daytime sleepiness and fatigue:relation to visceral obesity，insulin resistance，and hypercytokinemia[J].Am J Respir Crit Care Med，2000，85（3）:1151-1158..

West China Medical Journal

Study of the Risk Factors in Obstructive Sleep ApneaHypopnea Syndrome

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