Diagnosis and Treatment of 23 Cases with Primary Retroperitoneal Liposarcoma_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

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杜嘉林 , 吴泽宇 , 万进

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Keywords：

脂肪肉瘤; 腹膜后; 手术

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目的　总结原发性腹膜后脂肪肉瘤（primary retroperitoneal liposarcoma，PRL）的临床病理特征、诊断及治疗方法。
方法　回顾性分析经手术和活检证实的23例PRL患者的临床病理资料。
结果　首发症状及体征表现为腹部肿块（91.3%，21/23），腹胀（56.5%，13/23）及腹痛（30.4%，7/23）。B超及CT的定位诊断准确率分别为66.7%（12/18）和85.7%（12/14）。首次手术肿瘤完整切除16例（69.6%），其中8例联合脏器切除；部分切除3例（13.0%）；仅行活检4例（17.4%）。PRL肿瘤完整切除术后复发率为75.0%（12/16）,该12例中再次手术8例（66.7%）可完全切除肿瘤。
结论　CT是诊断PRL的重要手段，优于B超；手术以完整切除肿瘤为主，对侵犯脏器者采用累及脏器一并切除；术后复发者可再次手术。

Citation： 杜嘉林,吴泽宇,万进. Diagnosis and Treatment of 23 Cases with Primary Retroperitoneal Liposarcoma. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2007, 14(6): 704-705. doi: Copy

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1. 　Dalton RR, Donohue JH, Mucha P, et al. Management of retroperitoneal sarcomas [J]. Surgery, 1989; 106(4)∶725.
2. 　唐光健，王仪生，姜涛，等. 腹膜后原发肿瘤的CT诊断 [J]. 中华放射学杂志， 1996; 30(4)∶229.
3. 　Neville A, Herts BR. CT characteristics of primary retroperitoneal neoplasms [J]. Crit Rev Comput Tomogr, 2004; 45(4)∶247.
4. 　Erzen D, Sencar M, Novak J. Retroperitoneal sarcoma: 25 ye-ars of experience with aggressive surgical treatment at the institute of oncology, Ljubljana [J]. J Surg Oncol, 2005; 91(1)∶1.
5. 　Alldinger I, Yang Q, Pilarsky C, et al. Retroperitoneal soft tissue sarcomas: prognosis and treatment of primary and recurrent disease in 117 patients [J]. Anticancer Res, 2006; 26(2B)∶1577.
6. 　郑树森，徐骁. 原发性腹膜后及肠系膜脂肪肉瘤的诊断及外科治疗 [J]. 中国实用外科杂志， 2003； 23（9）∶540.
7. 　Singer S, Antonescu CR, Riedel E, et al. Histologic subtype and margin of resection predict pattern of recurrence and survival for retroperitoneal liposarcoma [J]. Ann Surg， 2003; 238(3)∶358.
8. 　Neuhaus SJ, Barry P, Clark MA, et al. Surgical management of primary and recurrent retroperitoneal liposarcoma [J]. Br J Surg， 2005; 92(2)∶246.
9. 　Malerba M, Doglietto GB, Pacelli F, et al. Primary retroperitoneal soft tissue sarcomas: results of aggressive surgical treatment [J]. World J Surg， 1999; 23(7)∶670.
10. 　Serio G, Tenchini P, Nifosi F, et al. Surgical strategy in primary retroperitoneal tumours [J]. Br J Surg， 1989; 76(4)∶385.

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Diagnosis and Treatment of 23 Cases with Primary Retroperitoneal Liposarcoma

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