目的 探讨原发性甲状旁腺功能亢进症(PHPT)的诊治经验。
方法 回顾性分析我院近15年间18例手术治疗的PHPT患者的临床资料。
结果 初诊病例术前核素99Tcm-sestamibi扫描和B超检查阳性定位诊断率分别为100%（9/9）和88%（15/17）。18例均经手术治疗，其中1例为再手术病例。术后病理诊断甲状旁腺腺瘤13例，其中1例为双腺瘤； 甲状旁腺增生4例； 甲状旁腺腺癌1例。首次手术治愈率为88%（15/17）。2例甲状旁腺增生病例未治愈。再手术1例因损伤了单侧喉返神经致术后声音嘶哑。
结论 术前核素99Tcm-sestamibi扫描和B超检查对制定手术方案有重要意义，大多数PHPT病例适合行单侧颈部探查术。甲状旁腺增生病例的手术治愈率低。
Citation：
解乃昌,林进令,陆云飞. Analysis of Diagnosis and Treatment of Primary Hyperparathyroidism. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2007, 14(1): 87-88. doi:
Copy
| 1. |
AACE/AAES Task Force on Primary Hyperparathyroidism. The American Association of Clinical Endocrinologists and the American Association of Endocrine Surgeons position statement on the diagnosis and management of primary hyperparathyroidism [Ｊ]. Endocr Pract, 2005; 11(1)∶49.
|
| 2. |
Inabnet WB. Intraoperative parathyroid hormone monitoring [Ｊ]. World J Surg, 2004; 28(12)∶1212.
|
| 3. |
Parikshak M, Castillo ED, Conrad MF, et al. Impact of hypercalcemia and parathyroid hormone level on the sensitivity of preoperative sestamibi scanning for priary hyperparathyroidism [Ｊ]. Am Surg, 2003; 69(5)∶393.
|
- 1. AACE/AAES Task Force on Primary Hyperparathyroidism. The American Association of Clinical Endocrinologists and the American Association of Endocrine Surgeons position statement on the diagnosis and management of primary hyperparathyroidism [Ｊ]. Endocr Pract, 2005; 11(1)∶49.
- 2. Inabnet WB. Intraoperative parathyroid hormone monitoring [Ｊ]. World J Surg, 2004; 28(12)∶1212.
- 3. Parikshak M, Castillo ED, Conrad MF, et al. Impact of hypercalcemia and parathyroid hormone level on the sensitivity of preoperative sestamibi scanning for priary hyperparathyroidism [Ｊ]. Am Surg, 2003; 69(5)∶393.
