Objective To analyse the clinico-pathological characteristics of young patients with colorectal cancer.
Methods From January 1980 to January 2000, among 1 030 patients with colorectal cancer admitted for surgical treatment, 143 (13.9%) patients were ＜35 years of age. The clinicopathological data of these young patients were reviewed and compared with those of patients in the other age groups.
Results In this series of young patients, males were predominat. Most of them were with poorly differentiated (37.8%) and muco-cellular (29.6%) adenocarcinoma. The mast common gross morphology was infiltrating type (56.6%) and colloid carcinoma type (31.5%). The majority of patients (89.5%) were in Dukes stage B and stage C.
Conclusion The prognosis of young patients with colorectal cancer surgically treated is worse, due to the fact that most of them are in late stage and their cancers are worse in differentiation. To increase the awareness of cancer in the young is important for early diagnosis and treatment and better prognosis.
Citation：
BAO Hongping,FANG Denghua,GAO Ruigang,LI Kui,ZHANG Xuesong,LIU Tianxi. ClinicoPathological Characteristics of Young Patients with Colorectal Cancer. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2004, 11(1): 52-54. doi:
Copy
Copyright © the editorial department of CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY of West China Medical Publisher. All rights reserved
| 1. |
Pisani P， Parkin DM， Bray F， et al. Estimates of the worldwide mortality from 25 cancers in 1990 [J]. Int J Cancer， 1999； 83（1）∶18.
|
| 2. |
大肠癌病理与预后关系研究协作组.国人青年人大肠癌的特点与预后 [J]. 中华肿瘤杂志， 1986； 8（2）∶146.
|
| 3. |
谭立新. 青年人大肠癌31例临床病理分析 [J]. 北京医学，1998； 20（5）∶314.
|
| 4. |
Lai IR， Lee WJ， Chen CN， et al. Gastric cancer in the young [J]. Hepatogastroenterology, 1997； 44(18)∶1641.
|
| 5. |
Furukawa H， Iwanaga T， Koyama H， et al. Effect of sex hormones on carcinogenesis in the stomachs of rats [J]. Cancer Res, 1982； 42（12）∶5181.
|
| 6. |
Nishi K， Tokunaga A， Shimizu Y， et al. Immunohistochemical study of intracellular estradiol in human gastric cancer [J]. Cancer， 1987； 59（7）∶1328.
|
| 7. |
Lo SS， Wu CW， Hsieh MC， et al. Relationship between age and clinical characteristics of patients with gastric cancer [J]. J Gastroenterol Hepatol, 1996； 11（6）∶511.
|
| 8. |
王吉甫主编.胃肠外科学 [M]. 北京： 人民卫生出版社， 2000∶937～938.
|
| 9. |
Moriguchi S， Maehara Y， Korenaga D， et al. Relationship between age and the time of surgery and prognosis after gastrectomy for gastric cancer [J]. J Surg Oncol， 1993； 52（2）∶ 119.
|
| 10. |
Kitamura K， Yamaguchi T， Yamamoto K， et al. Clinicopathological analysis of gastric cancer in young adults [J]. Hepatogastroenterology， 1996； 43（11）∶1273.
|
- 1. Pisani P， Parkin DM， Bray F， et al. Estimates of the worldwide mortality from 25 cancers in 1990 [J]. Int J Cancer， 1999； 83（1）∶18.
- 2. 大肠癌病理与预后关系研究协作组.国人青年人大肠癌的特点与预后 [J]. 中华肿瘤杂志， 1986； 8（2）∶146.
- 3. 谭立新. 青年人大肠癌31例临床病理分析 [J]. 北京医学，1998； 20（5）∶314.
- 4. Lai IR， Lee WJ， Chen CN， et al. Gastric cancer in the young [J]. Hepatogastroenterology, 1997； 44(18)∶1641.
- 5. Furukawa H， Iwanaga T， Koyama H， et al. Effect of sex hormones on carcinogenesis in the stomachs of rats [J]. Cancer Res, 1982； 42（12）∶5181.
- 6. Nishi K， Tokunaga A， Shimizu Y， et al. Immunohistochemical study of intracellular estradiol in human gastric cancer [J]. Cancer， 1987； 59（7）∶1328.
- 7. Lo SS， Wu CW， Hsieh MC， et al. Relationship between age and clinical characteristics of patients with gastric cancer [J]. J Gastroenterol Hepatol, 1996； 11（6）∶511.
- 8. 王吉甫主编.胃肠外科学 [M]. 北京： 人民卫生出版社， 2000∶937～938.
- 9. Moriguchi S， Maehara Y， Korenaga D， et al. Relationship between age and the time of surgery and prognosis after gastrectomy for gastric cancer [J]. J Surg Oncol， 1993； 52（2）∶ 119.
- 10. Kitamura K， Yamaguchi T， Yamamoto K， et al. Clinicopathological analysis of gastric cancer in young adults [J]. Hepatogastroenterology， 1996； 43（11）∶1273.
